Spontaneous coronary artery dissection history and symptoms

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Spontaneous Coronary Artery Dissection Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Spontaneous coronary artery dissection from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Approach

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Angiography

CT

MRI

Echocardiography

Other Imaging Findings

Other Diagnostic Studies

Treatment

Treatment Approach

Medical Therapy

Percutaneous Coronary Intervention

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Type 1

Type 2A

Type 2B

Type 3

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nate Michalak, B.A.

Synonyms and keywords: SCAD

Overview

History

Patients presenting with typical symptoms of acute coronary syndromes and the following clinical characteristics may have suspected spontaneous coronary artery dissection (SCAD):

  • Physical exertion[1]
  • Emotional stress[2]
  • Women with an average age ranging from 43 to 50 years[3][4]
  • Postpartum status or history of pregnancy[5]
  • Smoking
  • Atherosclerosis

Many patients do not have a previous history of cardiovascular disease or other risk factors and SCAD is idopathic[3]

Symptoms

The symptoms of SCAD mimic other acute coronary syndromes, with an acute and severe onset of chest pain that may radiate to jaw and left arm Patients may present with chronic stable angina, myocardial infarction,[6] cardiogenic shock, sudden death[7] and/or pericardial tamponade. 50% of sudden death cases were reported to have dissections in the left main coronary artery. Patients are typically asymptomatic on follow up.[6]

References

  1. Azam MN, Roberts DH, Logan WF (1995). "Spontaneous coronary artery dissection associated with oral contraceptive use". Int J Cardiol. 48 (2): 195–8. PMID 7775001.
  2. Saw, Jacqueline; Ricci, Donald; Starovoytov, Andrew; Fox, Rebecca; Buller, Christopher E. (2013). "Spontaneous Coronary Artery Dissection". JACC: Cardiovascular Interventions. 6 (1): 44–52. doi:10.1016/j.jcin.2012.08.017. ISSN 1936-8798.
  3. 3.0 3.1 Saw J, Aymong E, Sedlak T, Buller CE, Starovoytov A, Ricci D; et al. (2014). "Spontaneous coronary artery dissection: association with predisposing arteriopathies and precipitating stressors and cardiovascular outcomes". Circ Cardiovasc Interv. 7 (5): 645–55. doi:10.1161/CIRCINTERVENTIONS.114.001760. PMID 25294399.
  4. Tweet MS, Hayes SN, Pitta SR, Simari RD, Lerman A, Lennon RJ; et al. (2012). "Clinical features, management, and prognosis of spontaneous coronary artery dissection". Circulation. 126 (5): 579–88. doi:10.1161/CIRCULATIONAHA.112.105718. PMID 22800851.
  5. Vijayaraghavan, R.; Verma, S.; Gupta, N.; Saw, J. (2014). "Pregnancy-Related Spontaneous Coronary Artery Dissection". Circulation. 130 (21): 1915–1920. doi:10.1161/CIRCULATIONAHA.114.011422. ISSN 0009-7322.
  6. 6.0 6.1 Zampieri P, Aggio S, Roncon L, Rinuncini M, Canova C, Zanazzi G; et al. (1996). "Follow up after spontaneous coronary artery dissection: a report of five cases". Heart. 75 (2): 206–9. PMC 484263. PMID 8673763.
  7. Basso C, Morgagni GL, Thiene G (1996). "Spontaneous coronary artery dissection: a neglected cause of acute myocardial ischaemia and sudden death". Heart. 75 (5): 451–4. PMC 484340. PMID 8665336.