Spontaneous bacterial peritonitis screening: Difference between revisions

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** Periscreen strip is considered to be a good screening test in outpatients as it identified all patients with SBP.  
** Periscreen strip is considered to be a good screening test in outpatients as it identified all patients with SBP.  
** Further studies are needed to better understand pre-analytical conditions leading to the failure to recognize SBP among inpatients.<ref name="ThévenotBriot2016">{{cite journal|last1=Thévenot|first1=Thierry|last2=Briot|first2=Charline|last3=Macé|first3=Vincent|last4=Lison|first4=Hortensia|last5=Elkrief|first5=Laure|last6=Heurgué-Berlot|first6=Alexandra|last7=Bureau|first7=Christophe|last8=Jézéquel|first8=Caroline|last9=Riachi|first9=Ghassan|last10=Louvet|first10=Alexandre|last11=Pauwels|first11=Arnaud|last12=Ollivier-Hourmand|first12=Isabelle|last13=Anty|first13=Rodolphe|last14=Carbonell|first14=Nicolas|last15=Labadie|first15=Hélène|last16=Aziz|first16=Karim|last17=Grasset|first17=Denis|last18=Nguyen-Khac|first18=Eric|last19=Kaassis|first19=Mehdi|last20=Hermann|first20=Sofia|last21=Tanné|first21=Florence|last22=Mouillot|first22=Thomas|last23=Roux|first23=Olivier|last24=Le Thuaut|first24=Aurélie|last25=Cervoni|first25=Jean-Paul|last26=Cadranel|first26=Jean-François|last27=Schnee|first27=Matthieu|last28=Bardou-Jacquet|first28=Edouard|last29=Belouchrani|first29=Yasmina|last30=Bernard-Chabert|first30=Brigitte|last31=Canivet|first31=Clémence|last32=Dao|first32=Thong|last33=Di Martino|first33=Vincent|last34=Faroux|first34=Roger|last35=Medmoun|first35=Mourad|last36=Nousbaum|first36=Jean-Baptiste|last37=Riche|first37=Valéry-Pierre|last38=Robic|first38=Marie Angèle|last39=Si Nafa|first39=Si Ahmed|last40=Si Nafa|first40=Si Ahmed|last41=Thiéfin|first41=Gérard|last42=Weil|first42=Delphine|title=The Periscreen Strip Is Highly Efficient for the Exclusion of Spontaneous Bacterial Peritonitis in Cirrhotic Outpatients|journal=The American Journal of Gastroenterology|volume=111|issue=10|year=2016|pages=1402–1409|issn=0002-9270|doi=10.1038/ajg.2016.344}}</ref>
** Further studies are needed to better understand pre-analytical conditions leading to the failure to recognize SBP among inpatients.<ref name="ThévenotBriot2016">{{cite journal|last1=Thévenot|first1=Thierry|last2=Briot|first2=Charline|last3=Macé|first3=Vincent|last4=Lison|first4=Hortensia|last5=Elkrief|first5=Laure|last6=Heurgué-Berlot|first6=Alexandra|last7=Bureau|first7=Christophe|last8=Jézéquel|first8=Caroline|last9=Riachi|first9=Ghassan|last10=Louvet|first10=Alexandre|last11=Pauwels|first11=Arnaud|last12=Ollivier-Hourmand|first12=Isabelle|last13=Anty|first13=Rodolphe|last14=Carbonell|first14=Nicolas|last15=Labadie|first15=Hélène|last16=Aziz|first16=Karim|last17=Grasset|first17=Denis|last18=Nguyen-Khac|first18=Eric|last19=Kaassis|first19=Mehdi|last20=Hermann|first20=Sofia|last21=Tanné|first21=Florence|last22=Mouillot|first22=Thomas|last23=Roux|first23=Olivier|last24=Le Thuaut|first24=Aurélie|last25=Cervoni|first25=Jean-Paul|last26=Cadranel|first26=Jean-François|last27=Schnee|first27=Matthieu|last28=Bardou-Jacquet|first28=Edouard|last29=Belouchrani|first29=Yasmina|last30=Bernard-Chabert|first30=Brigitte|last31=Canivet|first31=Clémence|last32=Dao|first32=Thong|last33=Di Martino|first33=Vincent|last34=Faroux|first34=Roger|last35=Medmoun|first35=Mourad|last36=Nousbaum|first36=Jean-Baptiste|last37=Riche|first37=Valéry-Pierre|last38=Robic|first38=Marie Angèle|last39=Si Nafa|first39=Si Ahmed|last40=Si Nafa|first40=Si Ahmed|last41=Thiéfin|first41=Gérard|last42=Weil|first42=Delphine|title=The Periscreen Strip Is Highly Efficient for the Exclusion of Spontaneous Bacterial Peritonitis in Cirrhotic Outpatients|journal=The American Journal of Gastroenterology|volume=111|issue=10|year=2016|pages=1402–1409|issn=0002-9270|doi=10.1038/ajg.2016.344}}</ref>
* The diagnostic accuracy of leucocyte esterase reagent strips read out by a photospectrometer was comparable with the gold standard test and was excellent for excluding SBP. Our results support implementation of reagent strips in the diagnostic work-up of ascitic fluid.The sensitivity, specificity, positive predictive value and negative predictive value of the reagent strip according to the photospectrometer were 100%, 93%, 55% and 100% respectively, and 75%, 99%, 82% and 98%, respectively, for visual interpretation.<ref name="pmid27571723">{{cite journal| author=Oey RC, Kuiper JJ, van Buuren HR, de Man RA| title=Reagent strips are efficient to rule out spontaneous bacterial peritonitis in cirrhotics. | journal=Neth J Med | year= 2016 | volume= 74 | issue= 6 | pages= 257-61 | pmid=27571723 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27571723  }} </ref>


==References==
==References==

Revision as of 19:29, 22 January 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shivani Chaparala M.B.B.S [2]

Overview

Screening

  • Leukocyte esterase strip calibrated to an ascitic fluid neutrophil count 250/microl is an effective screening tool when the strip turns to any hue of brown at 3 min. [1]
  • Fecal calprotectin is a useful screening parameter for spontaneous bacterial peritonitis in cirrhosis. It is helpful in grading the severity of hepatic encephalopathy.[2][3]
  • A new Prescreen strip, is highly effective and cost-saving procedure for the exclusion of SBP in cirrhotic outpatients (due to its excellent NPV) without the need to perform standard ascitic cytology.
    • In outpatients, the performance of this strip was optimal with a sensitivity- 100% and negative predictive value-100%.
    • Periscreen strip is considered to be a good screening test in outpatients as it identified all patients with SBP.
    • Further studies are needed to better understand pre-analytical conditions leading to the failure to recognize SBP among inpatients.[4]
  • The diagnostic accuracy of leucocyte esterase reagent strips read out by a photospectrometer was comparable with the gold standard test and was excellent for excluding SBP. Our results support implementation of reagent strips in the diagnostic work-up of ascitic fluid.The sensitivity, specificity, positive predictive value and negative predictive value of the reagent strip according to the photospectrometer were 100%, 93%, 55% and 100% respectively, and 75%, 99%, 82% and 98%, respectively, for visual interpretation.[5]

References

  1. Mendler MH, Agarwal A, Trimzi M, Madrigal E, Tsushima M, Joo E; et al. (2010). "A new highly sensitive point of care screen for spontaneous bacterial peritonitis using the leukocyte esterase method". J Hepatol. 53 (3): 477–83. doi:10.1016/j.jhep.2010.04.011. PMID 20646775.
  2. Gundling F, Schmidtler F, Hapfelmeier A, Schulte B, Schmidt T, Pehl C; et al. (2011). "Fecal calprotectin is a useful screening parameter for hepatic encephalopathy and spontaneous bacterial peritonitis in cirrhosis". Liver Int. 31 (9): 1406–15. doi:10.1111/j.1478-3231.2011.02577.x. PMID 22093455.
  3. Fernandes, Samuel Raimundo; Santos, Patrícia; Fatela, Narcisa; Baldaia, Cilénia; Tato Marinho, Rui; Proença, Helena; Ramalho, Fernando; Velosa, José (2016). "Ascitic Calprotectin is a Novel and Accurate Marker for Spontaneous Bacterial Peritonitis". Journal of Clinical Laboratory Analysis. 30 (6): 1139–1145. doi:10.1002/jcla.21994. ISSN 0887-8013.
  4. Thévenot, Thierry; Briot, Charline; Macé, Vincent; Lison, Hortensia; Elkrief, Laure; Heurgué-Berlot, Alexandra; Bureau, Christophe; Jézéquel, Caroline; Riachi, Ghassan; Louvet, Alexandre; Pauwels, Arnaud; Ollivier-Hourmand, Isabelle; Anty, Rodolphe; Carbonell, Nicolas; Labadie, Hélène; Aziz, Karim; Grasset, Denis; Nguyen-Khac, Eric; Kaassis, Mehdi; Hermann, Sofia; Tanné, Florence; Mouillot, Thomas; Roux, Olivier; Le Thuaut, Aurélie; Cervoni, Jean-Paul; Cadranel, Jean-François; Schnee, Matthieu; Bardou-Jacquet, Edouard; Belouchrani, Yasmina; Bernard-Chabert, Brigitte; Canivet, Clémence; Dao, Thong; Di Martino, Vincent; Faroux, Roger; Medmoun, Mourad; Nousbaum, Jean-Baptiste; Riche, Valéry-Pierre; Robic, Marie Angèle; Si Nafa, Si Ahmed; Si Nafa, Si Ahmed; Thiéfin, Gérard; Weil, Delphine (2016). "The Periscreen Strip Is Highly Efficient for the Exclusion of Spontaneous Bacterial Peritonitis in Cirrhotic Outpatients". The American Journal of Gastroenterology. 111 (10): 1402–1409. doi:10.1038/ajg.2016.344. ISSN 0002-9270.
  5. Oey RC, Kuiper JJ, van Buuren HR, de Man RA (2016). "Reagent strips are efficient to rule out spontaneous bacterial peritonitis in cirrhotics". Neth J Med. 74 (6): 257–61. PMID 27571723.


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