Sobrerol

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Sobrerol
Clinical data
Synonymstrans-p-Menth-6-ene-2,8-diol; trans-sobrerol
ATC code
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC10H18O2
Molar mass170.249 g/mol
3D model (JSmol)
Melting point130−132 °C (−75.6 °F)
Boiling point270−271 °C (−185.8 °F)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Sobrerol is a mucolytic.

History

Sobrerol was discovered by Ascanio Sobrero as an oxidation product of terpenes. Later the oxidation and reduction reactions of chiral pinene lead also to several possible isomeres of Carvone and Sobrerol, making it possible to determin reaction mechanism and the strucural properties of pinene and of other terpenes.

References

  • G. G. Henderson, W. J. S. Eastburn (1909). "The conversion of pinene into sobrerol". J. Chem. Soc., Trans. 95: 1465–1466. doi:10.1039/CT9099501465.
  • H. E. Armstrong, W. J. Pope (1891). "Studies of the terpenes and allied compounds. Sobrerol, a product of the oxidation of terebenthene (oil of turpentine) in sunlight". J. Chem. Soc., Trans. 59: 315–320. doi:10.1039/CT8915900315.
  • H. Schmidt (1953). "Über cis- und trans-Sobrerol (optisch-aktives Pinolhydrat)". Chemische Berichte. 86 (11): 1437–1444. doi:10.1002/cber.19530861112.
  • Allegra L, Bossi R, Braga PC (1981). "Action of sobrerol on mucociliary transport". Respiration. 42 (2): 105–9.


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