Small cell carcinoma of the lung epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

Small cell lung cancer represents 13.4% of all lung cancers in the US and it is most common in white population.

Epidemiology

Incidence

  • The expected number for new cases of lung cancer in the United States for 2014 is 224,210.[1] small cell lung cancer represents 13.6% of all lung cancers. 30,397 cases per year of small cell lung cancer have been reported between 2007 and 2011.[2] The male to female ratio has decreased, and overall, the incidence of lung cancer has decreased.

Demographics

Age

  • Most small cell lung cancer occur in patients > 65 years of age. The incidence of small cell lung cancer in patients older than 65 years is 38.8 per 100,000, in comparison with 2.6 per 100,000 in patients younger than 65 years.[2]

Gender

  • Lung cancer is more prevalent in males, however, in the past decade this ratio has shifted. The male to female ratio has decreased and the incidence per gender has come closer. (US reported cases from 2006-2010: Male 116,000 vs Female 108,210).[2]
  • The incidence is decreasing in men but increasing in women.
  • In 1975, the incidence of small cell lung cancer in males was 10.33 per 100,000; and 3.79 per 100,000 in females. Compared to 2011, where the incidence of small cell lung cancer in males was 6.81 per 100,000; and 5.82 per 100,000 in females.


Small Cell Lung Cancer Incidence by Gender - SEER Cancer Statistics Review 1975-2011[2]

Race

  • African Americans have a high incidence of lung cancer overall, however, for small cell lung cancer the incidence is higher in white population.
  • For whites, the percentage for small cell lung cancer of the total cases of lung cancer between 2007 and 2011 is 14.1%; and for African Americans the percentage is 10.5%.[2]

References

  1. Siegel, Rebecca; Ma, Jiemin; Zou, Zhaohui; Jemal, Ahmedin (2014). "Cancer statistics, 2014". CA: A Cancer Journal for Clinicians. 64 (1): 9–29. doi:10.3322/caac.21208. ISSN 0007-9235.
  2. 2.0 2.1 2.2 2.3 2.4 Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z,Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds). SEER Cancer Statistics Review, 1975-2011, National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/csr/1975_2011/, based on November 2013 SEER data submission, posted to the SEER web site, April 2014.


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