Silent thyroiditis diagnostic criteria: Difference between revisions

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==Diagnostic Criteria==
==Diagnostic Criteria==
There are no established criteria for the diagnosis of silent thyroiditis. Decreased [[radioactive iodine]] uptake, elevated serum [[T3]], and [[T4]] are helpful in diagnosing silent thyroiditis. Histopathological is also important to differentiate silent thyroiditis from other forms of [[thyroiditis]].<ref name="pmid21278944">{{cite journal |vauthors=Walker P |title=Silent thyroiditis |journal=Can Fam Physician |volume=30 |issue= |pages=1337–9 |year=1984 |pmid=21278944 |pmc=2153523 |doi= |url=}}</ref><ref name="pmid22443972">{{cite journal |vauthors=Samuels MH |title=Subacute, silent, and postpartum thyroiditis |journal=Med. Clin. North Am. |volume=96 |issue=2 |pages=223–33 |year=2012 |pmid=22443972 |doi=10.1016/j.mcna.2012.01.003 |url=}}</ref><ref name="pmid23214066">{{cite journal |vauthors=Noh JY |title=[Silent thyroiditis and subacute thyroiditis] |language=Japanese |journal=Nippon Rinsho |volume=70 |issue=11 |pages=1945–50 |year=2012 |pmid=23214066 |doi= |url=}}</ref>
There are no established criteria for the diagnosis of silent thyroiditis. Decreased [[radioactive iodine]] uptake, elevated serum [[T3]], and [[T4]] are helpful in diagnosing silent thyroiditis. Histopathology is also important to differentiate silent thyroiditis from other forms of [[thyroiditis]].<ref name="pmid21278944">{{cite journal |vauthors=Walker P |title=Silent thyroiditis |journal=Can Fam Physician |volume=30 |issue= |pages=1337–9 |year=1984 |pmid=21278944 |pmc=2153523 |doi= |url=}}</ref><ref name="pmid22443972">{{cite journal |vauthors=Samuels MH |title=Subacute, silent, and postpartum thyroiditis |journal=Med. Clin. North Am. |volume=96 |issue=2 |pages=223–33 |year=2012 |pmid=22443972 |doi=10.1016/j.mcna.2012.01.003 |url=}}</ref><ref name="pmid23214066">{{cite journal |vauthors=Noh JY |title=[Silent thyroiditis and subacute thyroiditis] |language=Japanese |journal=Nippon Rinsho |volume=70 |issue=11 |pages=1945–50 |year=2012 |pmid=23214066 |doi= |url=}}</ref>


*Elevated serum [[T4]], [[T3]] '''in thyrotoxicosis'''
*Elevated serum [[T4]] and [[T3]] '''in thyrotoxicosis'''
*Elevated [[thyroglobulin]] concentrations  
*Elevated [[thyroglobulin]] concentrations  
*Decreased [[Radioactive iodine|RAIU]] (Radioactive iodine uptake)
*Decreased [[Radioactive iodine uptake|RAIU (Radioactive iodine uptake)]]
*Histopathological findings include:
*[[Histopathological]] findings include:
**[[Lymphocytic]] infiltration
**[[Lymphocytic]] infiltration
**The '''Absence''' of following:
**The '''Absence''' of following:
***Hurthle cells
***[[Hurthle cells]]
***[[Germinal centers]]
***[[Germinal centers]]
***[[Fibrosis]]
***[[Fibrosis]]
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<small>‡TFT; Thyroid function tests(TSH, T4, and T3), †[[Grave's disease]] is not a thyroiditis, *RAIU; Radioiodine uptake.††One third of [[Riedel's thyroiditis]] presents with [[hypothyroidism]].</small>  
<small>‡TFT; [[Thyroid function tests]]([[TSH]], [[T4]], and [[T3]]), †[[Grave's disease]] is not a thyroiditis, *RAIU; [[Radioiodine|Radioiodin]]<nowiki/>e uptake.</small>
<small>
 
<br>
<small>††One third of [[Riedel's thyroiditis]] presents with [[hypothyroidism]].</small><small> <ref name="urlThyroiditis: Differential Diagnosis and Management - American Family Physician">{{cite web |url=http://www.aafp.org/afp/2000/0215/p1047.html#afp20000215p1047-b7 |title=Thyroiditis: Differential Diagnosis and Management - American Family Physician |format= |work= |accessdate=}}</ref></small>
Table modified from <ref name="urlThyroiditis: Differential Diagnosis and Management - American Family Physician">{{cite web |url=http://www.aafp.org/afp/2000/0215/p1047.html#afp20000215p1047-b7 |title=Thyroiditis: Differential Diagnosis and Management - American Family Physician |format= |work= |accessdate=}}</ref></small>


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
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Latest revision as of 00:11, 30 July 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]

Overview

There are no established criteria for the diagnosis of silent thyroiditis. Decreased radioactive iodine uptake, elevated serum T3, and T4 are helpful in diagnosing silent thyroiditis. Histopathology is also important to differentiate silent thyroiditis from other forms of thyroiditis.

Diagnostic Criteria

There are no established criteria for the diagnosis of silent thyroiditis. Decreased radioactive iodine uptake, elevated serum T3, and T4 are helpful in diagnosing silent thyroiditis. Histopathology is also important to differentiate silent thyroiditis from other forms of thyroiditis.[1][2][3]

Stepwise clinical diagnosis of Silent thyroiditis

The following flowchart describes the clinical approach to the diagnosis of silent thyroiditis.

 
 
 
 
 
 
 
 
 
 
 
Neck pain
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Yes
 
 
 
 
 
 
 
 
 
 
No
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
RAIU*
 
 
 
 
 
 
 
 
 
 
Presenting symptoms and TFTs
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Increased
 
 
Decreased
 
 
 
 
 
Hyperthyroid
 
 
 
Hypothyroid
 
Euthyroid
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
RAIU*
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Suppurative thyroiditis
 
 
De Quervain's thyroiditis
 
 
 
Increased
 
Decreased
 
Hashimoto's thyroiditis
 
 
Riedel's thyroiditis††
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Grave's disease
 
Silent thyroiditis

Postpartum thyroiditis

‡TFT; Thyroid function tests(TSH, T4, and T3), †Grave's disease is not a thyroiditis, *RAIU; Radioiodine uptake.

††One third of Riedel's thyroiditis presents with hypothyroidism. [4]

References

  1. Walker P (1984). "Silent thyroiditis". Can Fam Physician. 30: 1337–9. PMC 2153523. PMID 21278944.
  2. Samuels MH (2012). "Subacute, silent, and postpartum thyroiditis". Med. Clin. North Am. 96 (2): 223–33. doi:10.1016/j.mcna.2012.01.003. PMID 22443972.
  3. Noh JY (2012). "[Silent thyroiditis and subacute thyroiditis]". Nippon Rinsho (in Japanese). 70 (11): 1945–50. PMID 23214066.
  4. "Thyroiditis: Differential Diagnosis and Management - American Family Physician".

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