Sideroblastic anemia (patient information): Difference between revisions
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==Who is at highest risk?== | ==Who is at highest risk?== | ||
* Common risk factors in the development of sideroblastic anemia are | |||
** Male gender (X-linked SA) | |||
** Family history of hereditary SA | |||
** Chronic alcohol abuse | |||
** Lead toxicity | |||
** Drugs | |||
**** Isoniazid | |||
**** Pyrazinamide | |||
**** Chloramphenicol | |||
**** Cycloserine | |||
**** Azathioprine | |||
** Copper deficiency | |||
** Pyridoxine deficiency | |||
** Hypothermia affecting mitochondrial functions | |||
** High dose zinc suppleme | |||
==Diagnosis== | ==Diagnosis== | ||
The diagnostic workup for sideroblastic include | |||
* Blood work (complete blood count, peripheral smear, iron studies) | |||
* Bone marrow aspiration. | |||
==When to seek urgent medical care?== | ==When to seek urgent medical care?== | ||
==Treatment options== | ==Treatment options== | ||
Revision as of 17:17, 10 August 2018
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Sideroblastic anemia |
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Sideroblastic anemia On the Web |
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anemia=Sideroblastic+anemia Ongoing Trials at Clinical Trials.gov |
Overview
What are the symptoms of Sideroblastic anemia?
- Headache
- Weaknes
- Fatigue
- Breathing difficulty
- Rapid pulse
- Irritibility
- Chest pain
What causes Sideroblastic anemia?
Sideroblastic anemia can be caused by heriditory or acquired factors.
Heriditory causes of sideroblastic anemia include
- Mutations in ALAS2, ABCB7, SCL19A2, GLRX5 and PSU1 genes.
- Pearson syndrome
- DIDMOAD syndrome
- Mitochondrial SLC25A38
- Erythropoietic protoporphyria
- Acquired causes of sideroblastic anemia include:[2][3]
- Myelodysplastic syndrome
- Nutritional deficiencies (copper, vitamin B6)
- Lead poisoning
- Zinc overdose
- Alcohol
- Drugs (anti-tuberculous agents, antibiotics, progesterone, chelators, busulfan)
- Hypothermia
Who is at highest risk?
- Common risk factors in the development of sideroblastic anemia are
- Male gender (X-linked SA)
- Family history of hereditary SA
- Chronic alcohol abuse
- Lead toxicity
- Drugs
- Isoniazid
- Pyrazinamide
- Chloramphenicol
- Cycloserine
- Azathioprine
- Copper deficiency
- Pyridoxine deficiency
- Hypothermia affecting mitochondrial functions
- High dose zinc suppleme
Diagnosis
The diagnostic workup for sideroblastic include
- Blood work (complete blood count, peripheral smear, iron studies)
- Bone marrow aspiration.