Short stature: Difference between revisions
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{{ | {{Infobox disease | | ||
Name = | Name = Short stature | | ||
ICD10 | Image = | | ||
ICD9 | Caption = | | ||
DiseasesDB = 18756 | | |||
ICD10 = {{ICD10|E|34|3|e|20}} | | |||
ICD9 = {{ICD9|783.43}} | | |||
ICDO = | | |||
OMIM = | | |||
MedlinePlus = 003271 | | |||
eMedicineSubj = ped | | |||
eMedicineTopic = 2087 | | |||
MeshID = | | |||
}} | }} | ||
'''Short stature''' refers to a [[height of a human being]] which is below expected. Shortness is a vague term without a precise definition and with significant relativity to context. Because of the lack of preciseness, there is often disagreement about the degree of shortness that should be called ''short''. | |||
{{ | The American Association of Clinical Endocrinologists defines "short stature" as height more than 2 [[standard deviation]]s below the [[mean (statistics)|mean]] for age and gender, which corresponds to the shortest 2.3% of individuals.<ref name="urlFDA Approves Humatrope for Short Stature">{{cite web |url=http://www.fda.gov/bbs/topics/answers/2003/ans01242.html |title=FDA Approves Humatrope for Short Stature |publisher = [[U.S. Food and Drug Administration]] | date = 2003-07-25 |accessdate= 2009-01-13}} {{Dead link|date=October 2010|bot=H3llBot}}</ref> | ||
== | |||
==Causes== | |||
Shortness in children and young adults nearly always results from below-average [[Human development (biology)|growth]] in childhood, while shortness in older adults usually results from loss of height due to [[kyphosis]] of the [[vertebral column|spine]] or collapsed [[vertebra]]e from [[osteoporosis]]. | |||
From a medical perspective, severe shortness can be a [[human variability|variation]] of normal, resulting from the interplay of multiple familial genes. It can also be due to one or more of many abnormal conditions, such as chronic (prolonged) [[hormone]] deficiency, [[malnutrition]], disease of a major organ system, mistreatment, treatment with certain drugs, [[chromosome|chromosomal]] deletions, [[genetic disease|inherited diseases]], [[birth defect]] [[syndrome]]s, bone structures fusing earlier than intended or many other causes. | |||
HGH deficiency may occur at any time during infancy or childhood, with the most obvious sign being a noticeable slowing of growth. The deficiency may be genetic. | |||
Increasing final height in children with short stature may be beneficial and could enhance HRQoL outcomes barring troublesome side effects and excessive cost of treatments.<ref name="urlHeight and Health-related Quality of Life">{{cite web |url=http://gghjournal.com/volume24/1/ab09.cfm |title=Height and Health-related Quality of Life |format= |work= |accessdate=}}</ref> | |||
==External links== | ==External links== | ||
Revision as of 17:18, 30 July 2012
| Short stature | |
| Classification and external resources | |
| ICD-10 | E34.3 |
|---|---|
| ICD-9 | 783.43 |
| DiseasesDB | 18756 |
| MedlinePlus | 003271 |
| eMedicine | ped/2087 |
Short stature refers to a height of a human being which is below expected. Shortness is a vague term without a precise definition and with significant relativity to context. Because of the lack of preciseness, there is often disagreement about the degree of shortness that should be called short.
The American Association of Clinical Endocrinologists defines "short stature" as height more than 2 standard deviations below the mean for age and gender, which corresponds to the shortest 2.3% of individuals.[1]
Causes
Shortness in children and young adults nearly always results from below-average growth in childhood, while shortness in older adults usually results from loss of height due to kyphosis of the spine or collapsed vertebrae from osteoporosis.
From a medical perspective, severe shortness can be a variation of normal, resulting from the interplay of multiple familial genes. It can also be due to one or more of many abnormal conditions, such as chronic (prolonged) hormone deficiency, malnutrition, disease of a major organ system, mistreatment, treatment with certain drugs, chromosomal deletions, inherited diseases, birth defect syndromes, bone structures fusing earlier than intended or many other causes.
HGH deficiency may occur at any time during infancy or childhood, with the most obvious sign being a noticeable slowing of growth. The deficiency may be genetic.
Increasing final height in children with short stature may be beneficial and could enhance HRQoL outcomes barring troublesome side effects and excessive cost of treatments.[2]
External links
Template:WH Template:WikiDoc Sources
- ↑ "FDA Approves Humatrope for Short Stature". U.S. Food and Drug Administration. 2003-07-25. Retrieved 2009-01-13.[dead link]