Sexcord/ stromal ovarian tumors history and symptoms

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Sexcord/ stromal ovarian tumors Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:  ; Maneesha Nandimandalam, M.B.B.S.[2]

Overview

The most common symptoms of sexcord/ stromal ovarian tumors include adnexal mass, bloating, urinary urgency or frequency, dysphagia(difficulty eating) or feeling full quickly, pelvic or abdominal pain. Less common symptoms of sexcord/ stromal ovarian tumors include lymphadenopathy, postmenopausal bleeding, typical features of bowel obstruction like nausea, vomiting, and distention. Specific symptoms pertinent to sexcord/ stromal ovarian tumors include hirsutism(excessive hairgrowth), virilization, menstrual changes like abnormal uterine bleeding, precocious puberty in children.

History and Symptoms

Common Symptoms/presentations

less common symptoms/presentations

Acute presentations

They can manifest themselves as bowel obstruction, pleural effusion and even venous thromboembolism

Symptoms specific to sexcord-stromal tumors

References

  1. Zheng G, Yu H, Kanerva A, Försti A, Sundquist K, Hemminki K (2018). "Familial risks of ovarian cancer by age at diagnosis, proband type and histology". PLoS ONE. 13 (10): e0205000. doi:10.1371/journal.pone.0205000. PMC 6169923. PMID 30281663.
  2. Olson SH, Mignone L, Nakraseive C, Caputo TA, Barakat RR, Harlap S (August 2001). "Symptoms of ovarian cancer". Obstet Gynecol. 98 (2): 212–7. PMID 11506835.
  3. Vine MF, Ness RB, Calingaert B, Schildkraut JM, Berchuck A (December 2001). "Types and duration of symptoms prior to diagnosis of invasive or borderline ovarian tumor". Gynecol. Oncol. 83 (3): 466–71. doi:10.1006/gyno.2001.6411. PMID 11733956.
  4. Yawn BP, Barrette BA, Wollan PC (October 2004). "Ovarian cancer: the neglected diagnosis". Mayo Clin. Proc. 79 (10): 1277–82. doi:10.4065/79.10.1277. PMID 15473410.
  5. Goff BA, Mandel LS, Melancon CH, Muntz HG (June 2004). "Frequency of symptoms of ovarian cancer in women presenting to primary care clinics". JAMA. 291 (22): 2705–12. doi:10.1001/jama.291.22.2705. PMID 15187051.
  6. Goff BA, Mandel LS, Drescher CW, Urban N, Gough S, Schurman KM, Patras J, Mahony BS, Andersen MR (January 2007). "Development of an ovarian cancer symptom index: possibilities for earlier detection". Cancer. 109 (2): 221–7. doi:10.1002/cncr.22371. PMID 17154394.
  7. Goff B (March 2012). "Symptoms associated with ovarian cancer". Clin Obstet Gynecol. 55 (1): 36–42. doi:10.1097/GRF.0b013e3182480523. PMID 22343227.
  8. Webb PM, Purdie DM, Grover S, Jordan S, Dick ML, Green AC (January 2004). "Symptoms and diagnosis of borderline, early and advanced epithelial ovarian cancer". Gynecol. Oncol. 92 (1): 232–9. PMID 14751164.
  9. Schultz KA, Harris AK, Schneider DT, Young RH, Brown J, Gershenson DM, Dehner LP, Hill DA, Messinger YH, Frazier AL (October 2016). "Ovarian Sex Cord-Stromal Tumors". J Oncol Pract. 12 (10): 940–946. doi:10.1200/JOP.2016.016261. PMC 5063189. PMID 27858560.
  10. Horta M, Cunha TM (2015). "Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists". Diagn Interv Radiol. 21 (4): 277–86. doi:10.5152/dir.2015.34414. PMC 4498422. PMID 26054417.
  11. Varras M, Vasilakaki T, Skafida E, Akrivis C (June 2011). "Clinical, ultrasonographic, computed tomography and histopathological manifestations of ovarian steroid cell tumour, not otherwise specified: our experience of a rare case with female virilisation and review of the literature". Gynecol. Endocrinol. 27 (6): 412–8. doi:10.3109/09513590.2010.495432. PMID 20586551.
  12. Outwater EK, Wagner BJ, Mannion C, McLarney JK, Kim B (1998). "Sex cord-stromal and steroid cell tumors of the ovary". Radiographics. 18 (6): 1523–46. doi:10.1148/radiographics.18.6.9821198. PMID 9821198.

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