Sexcord/ stromal ovarian tumors classification
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Differentiating Sexcord/ Stromal Ovarian Tumors from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maneesha Nandimandalam, M.B.B.S.[2]
Overview
Sexcord/ stromal ovarian tumors may be classified according to WHO into 3 subtypes: pure stromal tumors, pure sexcord tumors, mixed stromal and sexcord tumors. Histological classification of sexcord-stromal ovarian tumors includes granulosa stromal cell tumors, sertoli leydig cell tumors, gynandroblastoma, and unclassified.
Classification
WHO classification for ovarian sex cord-stromal tumors:[1][2][3][4][5]
- Pure stromal tumors
- Fibroma
- Cellular fibroma
- Thecoma
- Luteinized thecoma associated with sclerosing peritonitis
- Fibrosarcoma
- Sclerosing stromal tumor
- Signet-ring stromal tumor
- Microcystic stromal tumor
- Leydig cell tumor
- Steroid cell tumor
- Steroid cell tumor, malignant
- Pure sex cord tumors
- Adult granulosa cell tumor
- Juvenile granulosa cell tumor
- Sertoli cell tumor
- Sex cord tumor with annular tubules
- Mixed sex cord-stromal tumors
- Sertoli-Leydig cell tumors
- Well-differentiated
- Moderately differentiated with heterologous elements
- Poorly differentiated with heterologous elements
- Retiform with heterologous elements
- Sex cord-stromal tumours, NOS
- Sertoli-Leydig cell tumors
| Types | Subtypes |
| Pure stromal tumors |
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| Pure sex cord tumors |
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| Mixed sex cord-stromal tumors |
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| NOS, not otherwise specified | |
| Types | Subtypes |
| Granulosa‐stromal cell tumors | |
| Sertoli–Leydig cell tumors |
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| Gynandroblastoma | No specific subtypes |
| Unclassified | No specific subtypes |
International Agency for Research on Cancer Histologic Groups of Ovarian Tumors
Classification from International agency for research on cancer is summarized in the table: [2][7][3]
| Ovarian tumors |
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References
- ↑ 1.0 1.1 Horta M, Cunha TM (2015). "Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists". Diagn Interv Radiol. 21 (4): 277–86. doi:10.5152/dir.2015.34414. PMC 4498422. PMID 26054417.
- ↑ 2.0 2.1 2.2 Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J (April 2016). "The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications". Arch. Gynecol. Obstet. 293 (4): 695–700. doi:10.1007/s00404-016-4035-8. PMID 26894303.
- ↑ 3.0 3.1 3.2 Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J (October 2015). "Statement by the Kommission Ovar of the AGO: The New FIGO and WHO Classifications of Ovarian, Fallopian Tube and Primary Peritoneal Cancer". Geburtshilfe Frauenheilkd. 75 (10): 1021–1027. doi:10.1055/s-0035-1558079. PMC 4629993. PMID 26556905.
- ↑ 4.0 4.1 McCluggage WG (August 2011). "Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis". Pathology. 43 (5): 420–32. doi:10.1097/PAT.0b013e328348a6e7. PMID 21716157.
- ↑ 5.0 5.1 Chen, Vivien W.; Ruiz, Bernardo; Killeen, Jeffrey L.; Cot�, Timothy R.; Wu, Xiao Cheng; Correa, Catherine N.; Howe, Holly L. (2003). "Pathology and classification of ovarian tumors". Cancer. 97 (S10): 2631–2642. doi:10.1002/cncr.11345. ISSN 0008-543X. replacement character in
|last4=at position 4 (help) - ↑ Fuller, P.J.; Leung, D.; Chu, S. (2017). "Genetics and genomics of ovarian sex cord-stromal tumors". Clinical Genetics. 91 (2): 285–291. doi:10.1111/cge.12917. ISSN 0009-9163.
- ↑ "onlinelibrary.wiley.com".