Seminoma history and symptoms: Difference between revisions

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{{Seminoma}}
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==Overview==
==Overview==
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==Symptoms==
==Symptoms==
*Most common presentation of testicular seminoma is a painless testicular mass, although 45% will report a degree of testicular discomfort.<ref name="clinicslpresntatioontesticularseminoma1">Clinical presentation of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref>
*Bilateral tumors are rare (~2%) and are almost always asynchronous.
*Diagnosis following trauma is common as it draws the patient’s attention to the lump.
*[[Back pain]], [[abdominal discomfort]], or [[abdominal mass]] may be a presenting feature in the 25% of patients who have retroperitoneal nodal metastases.
*Presentation with distant or extranodal metastases is rare (5%).
** The majority of patients with [disease name] are asymptomatic. OR
** The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
** Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
=== History ===
Patients with [disease name]] may have a positive history of:
* [History finding 1]
* [History finding 2]
* [History finding 3]
=== Common Symptoms ===
=== Common Symptoms ===
*The painless [[testicular]] [[mass]] is the pathonomonic of the testicular cancer.<ref name="pmid9227931">{{cite journal |vauthors=Bosl GJ, Motzer RJ |title=Testicular germ-cell cancer |journal=N. Engl. J. Med. |volume=337 |issue=4 |pages=242–53 |date=July 1997 |pmid=9227931 |doi=10.1056/NEJM199707243370406 |url=}}</ref> Common [[symptoms]] of seminoma include:<ref name="MotzerAgarwal2012">{{cite journal|last1=Motzer|first1=Robert J.|last2=Agarwal|first2=Neeraj|last3=Beard|first3=Clair|last4=Bhayani|first4=Sam|last5=Bolger|first5=Graeme B.|last6=Buyyounouski|first6=Mark K.|last7=Carducci|first7=Michael A.|last8=Chang|first8=Sam S.|last9=Choueiri|first9=Toni K.|last10=Gupta|first10=Shilpa|last11=Hancock|first11=Steven L.|last12=Hudes|first12=Gary R.|last13=Jonasch|first13=Eric|last14=Kuzel|first14=Timothy M.|last15=Lau|first15=Clayton|last16=Levine|first16=Ellis G.|last17=Lin|first17=Daniel W.|last18=Margolin|first18=Kim A.|last19=Michaelson|first19=M. Dror|last20=Olencki|first20=Thomas|last21=Pili|first21=Roberto|last22=Ratliff|first22=Thomas W.|last23=Redman|first23=Bruce G.|last24=Robertson|first24=Cary N.|last25=Ryan|first25=Charles J.|last26=Sheinfeld|first26=Joel|last27=Wang|first27=Jue|last28=Wilder|first28=Richard B.|title=Testicular Cancer|journal=Journal of the National Comprehensive Cancer Network|volume=10|issue=4|year=2012|pages=502–535|issn=1540-1405|doi=10.6004/jnccn.2012.0050}}</ref><ref name="pmid9227931">{{cite journal |vauthors=Bosl GJ, Motzer RJ |title=Testicular germ-cell cancer |journal=N. Engl. J. Med. |volume=337 |issue=4 |pages=242–53 |date=July 1997 |pmid=9227931 |doi=10.1056/NEJM199707243370406 |url=}}</ref>
*The painless [[testicular]] [[mass]] is the pathonomonic of the testicular cancer.<ref name="pmid9227931">{{cite journal |vauthors=Bosl GJ, Motzer RJ |title=Testicular germ-cell cancer |journal=N. Engl. J. Med. |volume=337 |issue=4 |pages=242–53 |date=July 1997 |pmid=9227931 |doi=10.1056/NEJM199707243370406 |url=}}</ref><ref name="MotzerAgarwal2012" /><ref name="pmid28574809">{{cite journal |vauthors=Marko J, Wolfman DJ, Aubin AL, Sesterhenn IA |title=Testicular Seminoma and Its Mimics: From the Radiologic Pathology Archives |journal=Radiographics |volume=37 |issue=4 |pages=1085–1098 |date=2017 |pmid=28574809 |pmc=5548453 |doi=10.1148/rg.2017160164 |url=}}</ref>
***Painless [[lump]] in the [[testicle]]
*Common [[symptoms]] of seminoma include:<ref name="MotzerAgarwal2012">{{cite journal|last1=Motzer|first1=Robert J.|last2=Agarwal|first2=Neeraj|last3=Beard|first3=Clair|last4=Bhayani|first4=Sam|last5=Bolger|first5=Graeme B.|last6=Buyyounouski|first6=Mark K.|last7=Carducci|first7=Michael A.|last8=Chang|first8=Sam S.|last9=Choueiri|first9=Toni K.|last10=Gupta|first10=Shilpa|last11=Hancock|first11=Steven L.|last12=Hudes|first12=Gary R.|last13=Jonasch|first13=Eric|last14=Kuzel|first14=Timothy M.|last15=Lau|first15=Clayton|last16=Levine|first16=Ellis G.|last17=Lin|first17=Daniel W.|last18=Margolin|first18=Kim A.|last19=Michaelson|first19=M. Dror|last20=Olencki|first20=Thomas|last21=Pili|first21=Roberto|last22=Ratliff|first22=Thomas W.|last23=Redman|first23=Bruce G.|last24=Robertson|first24=Cary N.|last25=Ryan|first25=Charles J.|last26=Sheinfeld|first26=Joel|last27=Wang|first27=Jue|last28=Wilder|first28=Richard B.|title=Testicular Cancer|journal=Journal of the National Comprehensive Cancer Network|volume=10|issue=4|year=2012|pages=502–535|issn=1540-1405|doi=10.6004/jnccn.2012.0050}}</ref>
***[[Swelling]] of the testicle
**Painless [[lump]] in the [[testicle]]
***Feeling of heaviness in the [[scrotum]] or [[abdomen]]
**Testicular swelling and mild discomfort
***[[Lymphadenopathy]]
**Feeling of heaviness in the [[scrotum]] or [[abdomen]]
***[[Pain]] in the back or [[abdomen]]
**[[Lymphadenopathy]]
***[[Ascites]]
**[[Pain]] in the back or [[abdomen]]
***[[Weight loss]]
**[[Ascites]]
***[[Gynecomastia]]
**[[Weight loss]]
***[[Precocious puberty]]
**[[Gynecomastia]]
***[[Infertility]]
**[[Precocious puberty]]
**[[Infertility]]


*
=== Less Common Symptoms ===
*[[Dyspnea]]
*[[Hemoptysis]]
*[[Chest pain]]


==References==
==References==

Latest revision as of 14:13, 1 May 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]

Overview

Symptoms of seminoma include painless testicular mass with discomfort, back pain, abdominal discomfort, or abdominal mass.

Symptoms

Common Symptoms

Less Common Symptoms

References

  1. Bosl GJ, Motzer RJ (July 1997). "Testicular germ-cell cancer". N. Engl. J. Med. 337 (4): 242–53. doi:10.1056/NEJM199707243370406. PMID 9227931.
  2. 2.0 2.1 Motzer, Robert J.; Agarwal, Neeraj; Beard, Clair; Bhayani, Sam; Bolger, Graeme B.; Buyyounouski, Mark K.; Carducci, Michael A.; Chang, Sam S.; Choueiri, Toni K.; Gupta, Shilpa; Hancock, Steven L.; Hudes, Gary R.; Jonasch, Eric; Kuzel, Timothy M.; Lau, Clayton; Levine, Ellis G.; Lin, Daniel W.; Margolin, Kim A.; Michaelson, M. Dror; Olencki, Thomas; Pili, Roberto; Ratliff, Thomas W.; Redman, Bruce G.; Robertson, Cary N.; Ryan, Charles J.; Sheinfeld, Joel; Wang, Jue; Wilder, Richard B. (2012). "Testicular Cancer". Journal of the National Comprehensive Cancer Network. 10 (4): 502–535. doi:10.6004/jnccn.2012.0050. ISSN 1540-1405.
  3. Marko J, Wolfman DJ, Aubin AL, Sesterhenn IA (2017). "Testicular Seminoma and Its Mimics: From the Radiologic Pathology Archives". Radiographics. 37 (4): 1085–1098. doi:10.1148/rg.2017160164. PMC 5548453. PMID 28574809.

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