Seminoma epidemiology and demographics: Difference between revisions

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==Overview==
==Overview==
Testicular germ cell tumor accounts for around 1-2% of all malignancies in males up to the age of 65, but they are the most common nonhematologic malignancy in males 15-49 years old. Approximately 50% of germ cell tumours are seminomas. The mean age at diagnosis of testicular seminoma is between 15 and 35 years. This is about 5 to 10 years older than men with other germ cell tumors of the testis. Testicular seminoma usually affects individuals of the Caucasian race. African american individuals are less likely to develop testicular seminoma.
The [[incidence]] of testicular cancer is approximately 5.7 per 100,000 men per year based on 2011-2015 report in the United States. [[Testicular]] [[cancer]] is the most common type of cancer in young males. [[Germ cell tumors]] are about 98% of [[testicular]] [[cancer]]. About 55% of [[germ cell tumors]] are seminomas.The prevalence of [[testicular]] [[cancer]] is estimated to be  9,310 new cases in 2018. Seminoma commonly affects individuals young adults 15 and 35 years of age. Seminoma is usually first diagnosed among 34 years (median, 39.5 years). The majority of seminoma cases are reported in Europe, Scandinavia and North America.


==Epidemiology==
==Epidemiology==
===Prevalence===
Testicular germ cell tumor accounts for around 1-2% of all malignancies in males up to the age of 65, but they are the most common nonhematologic malignancy in males 15-49 years old. Approximately 50% of germ cell tumours are seminomas.<ref name="epidemiologyofseminoma">Epidemiology of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref>
===Age===
The mean age at diagnosis of testicular seminoma is between 15 and 35 years. This is about 5 to 10 years older than men with other germ cell tumors of the testis.<ref name="presentationofseminoma1">Presentation of seminoma. Wikipedia 2016. https://en.wikipedia.org/wiki/Seminoma. Accessed on February 25, 2016</ref>
===Race===
Testicular seminoma usually affects individuals of the Caucasian race. African american individuals are less likely to develop testicular seminoma.<ref name="epidemiologyofseminoma">Epidemiology of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref>
==Epidemiology and Demographics==
===Incidence===
===Incidence===
*The prevalence of seminoma is approximately per 100,000 individuals worldwide.
*The [[incidence]] of testicular cancer is approximately 5.7 per 100,000 men per year based on 2011-2015 report in the United States.<ref name="urlTesticular Cancer - Cancer Stat Facts">{{cite web |url=https://seer.cancer.gov/statfacts/html/testis.html |title=Testicular Cancer - Cancer Stat Facts |format= |work= |accessdate=}}</ref>
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.


===Prevalence===
===Prevalence===
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
*[[Testicular]] [[cancer]] is the most common type of cancer in young males.<ref name="pmid242041712">{{cite journal |vauthors=Shanmugalingam T, Soultati A, Chowdhury S, Rudman S, Van Hemelrijck M |title=Global incidence and outcome of testicular cancer |journal=Clin Epidemiol |volume=5 |issue= |pages=417–27 |date=October 2013 |pmid=24204171 |pmc=3804606 |doi=10.2147/CLEP.S34430 |url=https://dx.doi.org/10.2147/CLEP.S34430}}</ref><ref name="pmid30620402">{{cite journal |vauthors=Siegel RL, Miller KD, Jemal A |title=Cancer statistics, 2019 |journal=CA Cancer J Clin |volume=69 |issue=1 |pages=7–34 |date=January 2019 |pmid=30620402 |doi=10.3322/caac.21551 |url=}}</ref>
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
*[[Germ cell tumors]] are about 98% of [[testicular]] [[cancer]].<ref name="pmid20447912">{{cite journal |vauthors=Chia VM, Quraishi SM, Devesa SS, Purdue MP, Cook MB, McGlynn KA |title=International trends in the incidence of testicular cancer, 1973-2002 |journal=Cancer Epidemiol. Biomarkers Prev. |volume=19 |issue=5 |pages=1151–9 |date=May 2010 |pmid=20447912 |pmc=2867073 |doi=10.1158/1055-9965.EPI-10-0031 |url=}}</ref>
*The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
**About 55% of [[germ cell tumors]] are seminomas
 
*The prevalence of [[testicular]] [[cancer]] is estimated to be  9,310 new cases in 2018.<ref name="urlTesticular Cancer - Cancer Stat Facts">{{cite web |url=https://seer.cancer.gov/statfacts/html/testis.html |title=Testicular Cancer - Cancer Stat Facts |format= |work= |accessdate=}}</ref>
===Case-fatality rate/Mortality rate===
*In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
*The case-fatality rate/mortality rate of [disease name] is approximately [number range].


===Age===
===Age===
*Patients of all age groups may develop [disease name].
*Seminoma commonly affects individuals young adults 15 and 35  years of age.<ref name="CheTamboli2002">{{cite journal|last1=Che|first1=Mingxin|last2=Tamboli|first2=Pheroze|last3=Ro|first3=Jae Y.|last4=Park|first4=Dong Soo|last5=Ro|first5=Jung Sil|last6=Amato|first6=Robert J.|last7=Ayala|first7=Alberto G.|title=Bilateral testicular germ cell tumors|journal=Cancer|volume=95|issue=6|year=2002|pages=1228–1233|issn=0008-543X|doi=10.1002/cncr.10804}}</ref>
*The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
*Seminoma is usually first diagnosed among 34 years (median, 39.5 years).<ref name="pmid27184033">{{cite journal |vauthors=Di Gregorio M, Nollevaux MC, Lorge F, D'Hondt L |title=Metachronous testicular seminoma after radiotherapy and chemotherapy: a case report |journal=World J Surg Oncol |volume=14 |issue= |pages=147 |date=May 2016 |pmid=27184033 |pmc=4867539 |doi=10.1186/s12957-016-0902-9 |url=}}</ref>
*[Disease name] commonly affects individuals younger than/older than [number of years] years of age.  
*[Chronic disease name] is usually first diagnosed among [age group].
*[Acute disease name] commonly affects [age group].


===Race===
===Race===
*There is no racial predilection to [disease name].
*Seminoma usually affects individuals of the white race. Black individuals are less likely to develop seminoma (ratio of 5 : 1).<ref name="pmid19903067">{{cite journal |vauthors=McGlynn KA, Cook MB |title=Etiologic factors in testicular germ-cell tumors |journal=Future Oncol |volume=5 |issue=9 |pages=1389–402 |date=November 2009 |pmid=19903067 |pmc=3000220 |doi=10.2217/fon.09.116 |url=}}</ref>
*[Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
===Gender===
===Gender===
*[Disease name] affects men and women equally.
*Seminoma affects exclusively in men.
*[Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.


===Region===
===Region===

Latest revision as of 13:33, 15 May 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]

Overview

The incidence of testicular cancer is approximately 5.7 per 100,000 men per year based on 2011-2015 report in the United States. Testicular cancer is the most common type of cancer in young males. Germ cell tumors are about 98% of testicular cancer. About 55% of germ cell tumors are seminomas.The prevalence of testicular cancer is estimated to be 9,310 new cases in 2018. Seminoma commonly affects individuals young adults 15 and 35 years of age. Seminoma is usually first diagnosed among 34 years (median, 39.5 years). The majority of seminoma cases are reported in Europe, Scandinavia and North America.

Epidemiology

Incidence

  • The incidence of testicular cancer is approximately 5.7 per 100,000 men per year based on 2011-2015 report in the United States.[1]

Prevalence

Age

  • Seminoma commonly affects individuals young adults 15 and 35 years of age.[5]
  • Seminoma is usually first diagnosed among 34 years (median, 39.5 years).[6]

Race

  • Seminoma usually affects individuals of the white race. Black individuals are less likely to develop seminoma (ratio of 5 : 1).[7]

Gender

  • Seminoma affects exclusively in men.

Region

  • The majority of seminoma cases are reported in Europe, Scandinavia and North America.[8]

References

  1. ↑ 1.0 1.1 "Testicular Cancer - Cancer Stat Facts".
  2. ↑ Shanmugalingam T, Soultati A, Chowdhury S, Rudman S, Van Hemelrijck M (October 2013). "Global incidence and outcome of testicular cancer". Clin Epidemiol. 5: 417–27. doi:10.2147/CLEP.S34430. PMC 3804606. PMID 24204171.
  3. ↑ Siegel RL, Miller KD, Jemal A (January 2019). "Cancer statistics, 2019". CA Cancer J Clin. 69 (1): 7–34. doi:10.3322/caac.21551. PMID 30620402.
  4. ↑ Chia VM, Quraishi SM, Devesa SS, Purdue MP, Cook MB, McGlynn KA (May 2010). "International trends in the incidence of testicular cancer, 1973-2002". Cancer Epidemiol. Biomarkers Prev. 19 (5): 1151–9. doi:10.1158/1055-9965.EPI-10-0031. PMC 2867073. PMID 20447912.
  5. ↑ Che, Mingxin; Tamboli, Pheroze; Ro, Jae Y.; Park, Dong Soo; Ro, Jung Sil; Amato, Robert J.; Ayala, Alberto G. (2002). "Bilateral testicular germ cell tumors". Cancer. 95 (6): 1228–1233. doi:10.1002/cncr.10804. ISSN 0008-543X.
  6. ↑ Di Gregorio M, Nollevaux MC, Lorge F, D'Hondt L (May 2016). "Metachronous testicular seminoma after radiotherapy and chemotherapy: a case report". World J Surg Oncol. 14: 147. doi:10.1186/s12957-016-0902-9. PMC 4867539. PMID 27184033.
  7. ↑ McGlynn KA, Cook MB (November 2009). "Etiologic factors in testicular germ-cell tumors". Future Oncol. 5 (9): 1389–402. doi:10.2217/fon.09.116. PMC 3000220. PMID 19903067.
  8. ↑ Shanmugalingam T, Soultati A, Chowdhury S, Rudman S, Van Hemelrijck M (October 2013). "Global incidence and outcome of testicular cancer". Clin Epidemiol. 5: 417–27. doi:10.2147/CLEP.S34430. PMC 3804606. PMID 24204171.

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