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First episode and well-tolerated atrial flutterCardioversion alone (class I, level of evidence B)
or
Catheter ablation (class IIa, level of evidence B)
 
Recurrent and well-tolerated atrial flutterCatheter ablation(class I, level of evidence B)
or
Dofetilide (class IIa, level of evidence C)
or
Amiodarone (class IIb, level of evidence C)
or
Sotalol
or
Flecainide
or
Quinidine
or
Propafenone
or
Procainamide
or
Disopyramide
 
Poorly tolerated atrial flutterCatheter ablation (class I, level of evidence B)
 
Atrial flutter appearing after use of class Ic agents or amiodarone for treatment of AFCatheter ablation (class I, level of evidence B)
or
Stop current drug and use another (class IIa, level of evidence C)
 
Symptomatic non–CTI-dependent flutter after failed antiarrhythmic drug therapyCatheter ablation (class IIa, level of evidence B)