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Note: A 9– to 12–month course of treatment is recommended for tuberculous meningitis. | Note (1): In tuberculous meningitis, ethambutol should be replaced by streptomycin. | ||
Note (2): A 9– to 12–month course of treatment is recommended for tuberculous meningitis. | |||
Note (3): Adjuvant corticosteroid treatment is recommended unless drug resistance is suspected. | |||
Revision as of 06:44, 8 June 2015
Meningitis, tuberculous ⇧ Return to Top ⇧
- Preferred regimen: 2 months of Isoniazid 5 (4–6)mg/kg OD AND Rifampicin 10 (8–12)mg/kg OD AND Pyrazinamide 25 (20–30)mg/kg OD AND Streptomycin 15 (12–18)mg/kg OD followed by 7-10 months of Isoniazid 5 (4–6)mg/kg OD AND Rifampicin 10 (8–12)mg/kg OD
- Alternative regimen (1): 2 months of Isoniazid 5 (4–6)mg/kg OD AND Rifampicin 10 (8–12)mg/kg OD AND Pyrazinamide 25 (20–30)mg/kg OD AND Streptomycin 15 (12–18)mg/kg OD followed by 7-10 months of Isoniazid 10 (8–12)mg/kg 3 times per week AND Rifampicin 10 (8–12)mg/kg 3 times per week
- Alternative regimen (2): 2 months of Isoniazid 10 (8–12)mg/kg 3 times per week AND Rifampicin 10 (8–12)mg/kg 3 times per week AND Pyrazinamide 35 (30–40)mg/kg 3 times per week AND Streptomycina 15 (12–18)mg/kg 3 times per week followed by 7-10 months of Isoniazid 10 (8–12)mg/kg 3 times per week AND Rifampicin 10 (8–12)mg/kg 3 times per week
Note (1): In tuberculous meningitis, ethambutol should be replaced by streptomycin.
Note (2): A 9– to 12–month course of treatment is recommended for tuberculous meningitis.
Note (3): Adjuvant corticosteroid treatment is recommended unless drug resistance is suspected.
- ↑ Blumberg, Henry M.; Burman, William J.; Chaisson, Richard E.; Daley, Charles L.; Etkind, Sue C.; Friedman, Lloyd N.; Fujiwara, Paula; Grzemska, Malgosia; Hopewell, Philip C.; Iseman, Michael D.; Jasmer, Robert M.; Koppaka, Venkatarama; Menzies, Richard I.; O'Brien, Richard J.; Reves, Randall R.; Reichman, Lee B.; Simone, Patricia M.; Starke, Jeffrey R.; Vernon, Andrew A.; American Thoracic Society, Centers for Disease Control and Prevention and the Infectious Diseases Society (2003-02-15). "American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: treatment of tuberculosis". American Journal of Respiratory and Critical Care Medicine. 167 (4): 603–662. doi:10.1164/rccm.167.4.603. ISSN 1073-449X. PMID 12588714.
- ↑ Treatment of Tuberculosis: Guidelines. WHO Guidelines Approved by the Guidelines Review Committee (4th ed.). Geneva: World Health Organization. 2010. ISBN 9789241547833. PMID 23741786. Retrieved 2015-06-08.