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Overview

Venous thromboembolism (VTE) consists of deep vein thrombosis (DVT), pulmonary embolism (PE), or both. The risk factors for VTE are a constellation of predisposing conditions which stem from the three principles of Virchow's triad: stasis of the blood flow, damage to the vascular endothelial cells, and hypercoagulability. The risk factors for VTE can be categorized as temporary, modifiable and non-modifiable. Venous thrombosis also shares risk factors with cardiac thrombosis, such as obesity, hypertension and smoking.

Risk Factors

Shown below is a list of predisposing factors to VTE.[1]

Identify predisposing factors:[2]
Strong risk factors Moderate risk factors Weak risk factors
Bone fracture (hip or leg)

Hip replacement surgery
❑ Knee replacement surgery
Major general surgery
Significant trauma
Spinal cord injury

❑ Athroscopic knee surgery

Central venous lines
Chemotherapy
Chronic heart failure
Respiratory failure
Hormone replacement therapy
Cancer
Oral contraceptive pills
Stroke
Pregnancy
Postpartum
❑ Prior history of VTE
Thrombophilia

❑ Bed rest for more than 3 days

❑ Prolonged car or air travel
❑ Advanced age
Laparoscopic surgery
❑ Prepartum
Obesity
Varicose veins

References

  1. Anderson FA, Spencer FA (2003). "Risk factors for venous thromboembolism". Circulation. 107 (23 Suppl 1): I9–16. doi:10.1161/01.CIR.0000078469.07362.E6. PMID 12814980.
  2. Torbicki A, Perrier A, Konstantinides S, Agnelli G, Galiè N, Pruszczyk P; et al. (2008). "Guidelines on the diagnosis and management of acute pulmonary embolism: the Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC)". Eur Heart J. 29 (18): 2276–315. doi:10.1093/eurheartj/ehn310. PMID 18757870.