Sandbox MWH: Difference between revisions

Revision as of 16:18, 14 August 2020

Year	Discovery
1877	First-ever description of narcolepsy in the medical literature
1880	Gelineau named the disorder “narcolepsy”
1902	Loewenfeld first coined the term “cataplexy”
1935	First-ever use of amphetamines in the treatment of narcolepsy
1960	Description of Sleep Onset REM in patients with narcolepsy
1970	Multiple Latency Test description
1973	First-ever report of narcolepsy in a canine
1983	Association of HLA-DR2 with narcolepsy
1992	Association of HLA-DQB1*0602 with narcolepsy
1998	Hypocretins (orexins) and their receptors identification
2000	Association between Human narcolepsy and hypocretin deficiency

@@ Line 7: / Line 7: @@
 ! style="background: #DCDCDC; text-align: center;" |'''1877'''
 | style="background: #F5F5F5;" |
-* First-ever description of narcolepsy in the medical literature
+* First-ever description of narcolepsy in the [[medical literature]]
 |-
 ! style="background: #DCDCDC; text-align: center;" |'''1880'''
 | style="background: #F5F5F5;" |
-* Gelineau named the disorder “narcolepsy”
+* Gelineau named the [[disorder]] “narcolepsy”
 |-
 ! style="background: #DCDCDC; text-align: center;" |'''1902'''
 | style="background: #F5F5F5;" |
-*Loewenfeld first coined the term “cataplexy”
+*Loewenfeld first coined the term “[[cataplexy]]”
 |-
 ! style="background: #DCDCDC; text-align: center;" |'''1935'''
 | style="background: #F5F5F5;" |
-* First-ever use of amphetamines in the treatment of narcolepsy
+* First-ever use of [[amphetamines]] in the [[treatment]] of narcolepsy
 |-
 ! style="background: #DCDCDC; text-align: center;" |'''1960'''
 | style="background: #F5F5F5;" |
-* Description of Sleep Onset REM in patients with narcolepsy
+* Description of [[Sleep]] Onset [[REM sleep|REM]] in [[patients]] with narcolepsy
 |-
 ! style="background: #DCDCDC; text-align: center;" |'''1970'''
@@ Line 31: / Line 31: @@
 ! style="background: #DCDCDC; text-align: center;" |'''1973'''
 | style="background: #F5F5F5;" |
-* First-ever report of narcolepsy in a canine
+* First-ever report of narcolepsy in a [[canine]]
 |-
 ! style="background: #DCDCDC; text-align: center;" |'''1983'''
 | style="background: #F5F5F5;" |
-* Association of HLA-DR2 with narcolepsy
+*[[Association (statistics)|Association]] of [[HLA-DR2]] with narcolepsy
 |-
 ! style="background: #DCDCDC; text-align: center;" |'''1992'''
 | style="background: #F5F5F5;" |
-* Association of HLA-DQB1*0602 with narcolepsy
+*[[Association (statistics)|Association]] of [[HLA-DQB1]]*0602 with narcolepsy
 |-
 ! style="background: #DCDCDC; text-align: center;" |'''1998'''
 | style="background: #F5F5F5;" |
-* Hypocretins (orexins) and their receptors identification
+*[[Hypocretin|Hypocretins]] ([[orexins]]) and their [[receptors]] identification
 |-
 ! style="background: #DCDCDC; text-align: center;" |2000
 | style="background: #F5F5F5;" |
-* Association between Human narcolepsy and hypocretin deficiency
+*[[Association (statistics)|Association]] between [[Human]] narcolepsy and [[hypocretin]] [[deficiency]]
 |}
-Table 1: A few milestones in narcolepsy research and therapy
-First description in the medical literature (100)
-Gelineau called the disorder “narcolepsy” (28)
-Loewenfeld coined the term “cataplexy” (53)
-First use of amphetamines in the treatment of narcolepsy (87)
-Description of Sleep Onset REM periods in a narcoleptic subject (99)
-Description of the Multiple Latency Test (15, 90)
-First report of a narcoleptic dog (47, 72)
-Association of narcolepsy with HLA-DR2 (37)
-Monoaminergic and cholinergic imbalance in narcolepsy (7, 80)
-Association of narcolepsy with HLA-DQB1*0602 (56, 63)
-Identification of hypocretins/orexins and their receptors (18, 93)
-Hypocretin mutations cause narcolepsy in mice and dogs (16, 51)
-Human narcolepsy is also associated with an hypocretin deficiency (81)

Sandbox MWH: Difference between revisions

Revision as of 16:18, 14 August 2020

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