Sandbox ID Genitourinary: Difference between revisions

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===Chancroid===
{{Details-tx|Chancroid medical therapy}}


:* [[Chancroid]]<ref name="pmid21160459">{{cite journal| author=Workowski KA, Berman S, Centers for Disease Control and Prevention (CDC)| title=Sexually transmitted diseases treatment guidelines, 2010. | journal=MMWR Recomm Rep | year= 2010 | volume= 59 | issue= RR-12 | pages= 1-110 | pmid=21160459 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21160459  }} </ref>
* '''Chancroid'''<ref name="pmid21160459">{{cite journal| author=Workowski KA, Berman S, Centers for Disease Control and Prevention (CDC)| title=Sexually transmitted diseases treatment guidelines, 2010. | journal=MMWR Recomm Rep | year= 2010 | volume= 59 | issue= RR-12 | pages= 1-110 | pmid=21160459 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21160459  }} </ref>
::* Preferred regimen: [[Azithromycin]] 1 g orally in a single dose {{or}} [[Ceftriaxone]] 250 mg intramuscularly (IM) in a single dose) {{or}} [[Ciprofloxacin]] 500 mg orally twice a day for 3 days {{or}} [[Erythromycin]] base 500 mg orally three times a day for 7 days
:* Preferred regimen: [[Azithromycin]] 1 g orally in a single dose {{or}} [[Ceftriaxone]] 250 mg intramuscularly (IM) in a single dose) {{or}} [[Ciprofloxacin]] 500 mg orally twice a day for 3 days {{or}} [[Erythromycin]] base 500 mg orally three times a day for 7 days
::* Ciprofloxacin is contraindicated for pregnant and lactating women.
:* Ciprofloxacin is contraindicated for pregnant and lactating women.


----
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:* [[Gonococcal infection]]s<ref name="pmid21160459">{{cite journal| author=Workowski KA, Berman S, Centers for Disease Control and Prevention (CDC)| title=Sexually transmitted diseases treatment guidelines, 2010. | journal=MMWR Recomm Rep | year= 2010 | volume= 59 | issue= RR-12 | pages= 1-110 | pmid=21160459 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21160459  }} </ref><ref name="pmid22874837">{{cite journal| author=Centers for Disease Control and Prevention (CDC)| title=Update to CDC's Sexually transmitted diseases treatment guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections. | journal=MMWR Morb Mortal Wkly Rep | year= 2012 | volume= 61 | issue= 31 | pages= 590-4 | pmid=22874837 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22874837  }} </ref>
===Gonococcal infection===
::* '''Uncomplicated Gonococcal Infections of the Cervix, Urethra, and Rectum'''
{{Details-tx|Gonococcal infection medical therapy}}
:::* Preferred regimen: [[Ceftriaxone]] 250 mg intramuscularly {{and}} ([[Azithromycin]] 1 g orally as a single dose {{or}} [[Doxycycline]] 100 mg orally twice daily for 7 days)
:::* Alternative regimen: [[Cefuroxime]] 1 g orally
::* '''Uncomplicated Gonococcal Infections of the Pharynx'''
:::* Preferred regimen: [[Ceftriaxone]] 250 mg IM in a single dose {{and}} ([[Azithromycin]] 1 g orally as a single dose {{or}} [[Doxycycline]] 100 mg orally twice daily for 7 days)
::* '''Gonococcal Conjunctivitis'''
:::* Preferred regimen: [[Ceftriaxone]] 1 g IM in a single dose
::* '''Disseminated Gonococcal Infection (DGI)'''
:::* Preferred regimen: [[Ceftriaxone]] 1 g IV/IM every 24 hours
:::* Alternative regimen: [[Cefotaxime]] 1 g IV every 8 hours {{or}} [[Ceftizoxime]] 1 g IV every 8 hours
:::* All of the preceding regimens should be continued for 24-48 hours after improvement begins, at which time therapy can be switched to cefixime 400 mg orally twice daily to complete at least 1 week of antimicrobial therapy. No treatment failures have been reported with the recommended regimens.
::* '''Gonococcal Meningitis '''
:::* Preferred regimen: [[Ceftriaxone]] 1-2 g IV every 12 hours for 10-14 days
::* '''Gonococcal Endocarditis'''
:::* Preferred regimen: [[Ceftriaxone]] 1-2 g IV every 12 hours for at least 4 weeks
::* '''Gonococcal Infections Among Infants'''
:::* Ophthalmia Neonatorum Caused by N. gonorrhoeae
::::* Preferred regimen: [[Ceftriaxone]] 25-50 mg/kg IV or IM in a single dose, not to exceed 125 mg


:::* DGI and Gonococcal Scalp Abscesses in Newborns
* '''Gonococcal infection'''<ref name="pmid21160459">{{cite journal| author=Workowski KA, Berman S, Centers for Disease Control and Prevention (CDC)| title=Sexually transmitted diseases treatment guidelines, 2010. | journal=MMWR Recomm Rep | year= 2010 | volume= 59 | issue= RR-12 | pages= 1-110 | pmid=21160459 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21160459  }} </ref><ref name="pmid22874837">{{cite journal| author=Centers for Disease Control and Prevention (CDC)| title=Update to CDC's Sexually transmitted diseases treatment guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections. | journal=MMWR Morb Mortal Wkly Rep | year= 2012 | volume= 61 | issue= 31 | pages= 590-4 | pmid=22874837 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22874837  }} </ref>
:* '''Uncomplicated Gonococcal Infections of the Cervix, Urethra, and Rectum'''
::* Preferred regimen: [[Ceftriaxone]] 250 mg intramuscularly {{and}} ([[Azithromycin]] 1 g orally as a single dose {{or}} [[Doxycycline]] 100 mg orally twice daily for 7 days)
::* Alternative regimen: [[Cefuroxime]] 1 g orally


:* '''Uncomplicated Gonococcal Infections of the Pharynx'''
::* Preferred regimen: [[Ceftriaxone]] 250 mg IM in a single dose {{and}} ([[Azithromycin]] 1 g orally as a single dose {{or}} [[Doxycycline]] 100 mg orally twice daily for 7 days)


:* '''Gonococcal Conjunctivitis'''
::* Preferred regimen: [[Ceftriaxone]] 1 g IM in a single dose
:* '''Disseminated Gonococcal Infection (DGI)'''
::* Preferred regimen: [[Ceftriaxone]] 1 g IV/IM every 24 hours
::* Alternative regimen: [[Cefotaxime]] 1 g IV every 8 hours {{or}} [[Ceftizoxime]] 1 g IV every 8 hours
::: Note: All of the preceding regimens should be continued for 24-48 hours after improvement begins, at which time therapy can be switched to cefixime 400 mg orally twice daily to complete at least 1 week of antimicrobial therapy.
:* '''Gonococcal Meningitis '''
::* Preferred regimen: [[Ceftriaxone]] 1-2 g IV every 12 hours for 10-14 days
:* '''Gonococcal Endocarditis'''
::* Preferred regimen: [[Ceftriaxone]] 1-2 g IV every 12 hours for at least 4 weeks
:* Gonococcal Infections Among Infants
::* '''Ophthalmia Neonatorum Caused by N. gonorrhoeae'''
:::* Preferred regimen: [[Ceftriaxone]] 25-50 mg/kg IV or IM in a single dose, not to exceed 125 mg
::* '''DGI and Gonococcal Scalp Abscesses in Newborns'''
:::* Preferred regimen:




Revision as of 18:55, 27 May 2015

Chancroid

Further information: Chancroid medical therapy and therapeutic approach
  • Preferred regimen: Azithromycin 1 g orally in a single dose OR Ceftriaxone 250 mg intramuscularly (IM) in a single dose) OR Ciprofloxacin 500 mg orally twice a day for 3 days OR Erythromycin base 500 mg orally three times a day for 7 days
  • Ciprofloxacin is contraindicated for pregnant and lactating women.

Gonococcal infection

Further information: Gonococcal infection medical therapy and therapeutic approach
  • Uncomplicated Gonococcal Infections of the Cervix, Urethra, and Rectum
  • Uncomplicated Gonococcal Infections of the Pharynx
  • Gonococcal Conjunctivitis
  • Disseminated Gonococcal Infection (DGI)
Note: All of the preceding regimens should be continued for 24-48 hours after improvement begins, at which time therapy can be switched to cefixime 400 mg orally twice daily to complete at least 1 week of antimicrobial therapy.
  • Gonococcal Meningitis
  • Preferred regimen: Ceftriaxone 1-2 g IV every 12 hours for 10-14 days
  • Gonococcal Endocarditis
  • Preferred regimen: Ceftriaxone 1-2 g IV every 12 hours for at least 4 weeks
  • Gonococcal Infections Among Infants
  • Ophthalmia Neonatorum Caused by N. gonorrhoeae
  • Preferred regimen: Ceftriaxone 25-50 mg/kg IV or IM in a single dose, not to exceed 125 mg
  • DGI and Gonococcal Scalp Abscesses in Newborns
  • Preferred regimen:








References

  1. ↑ 1.0 1.1 Workowski KA, Berman S, Centers for Disease Control and Prevention (CDC) (2010). "Sexually transmitted diseases treatment guidelines, 2010". MMWR Recomm Rep. 59 (RR-12): 1–110. PMID 21160459.
  2. ↑ Centers for Disease Control and Prevention (CDC) (2012). "Update to CDC's Sexually transmitted diseases treatment guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections". MMWR Morb Mortal Wkly Rep. 61 (31): 590–4. PMID 22874837.
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