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Overview

The hallmark of Hepatic Encephalopathy is accumulation of ammonia and toxic substances in the blood that are normally detoxified in the liver. A positive history of and is suggestive of . The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History and Symptoms

Hepatic encephalopathy or portosystemic encephalopathy is a syndrome of largely reversible impairment of brain function occurring in patients with acute or chronic liver failure or when the liver is bypassed by portosystemic shunts.[1]Hepatic encephalopathy (HE) is a common problem in liver cirrhosis and is associated with typical changes of cerebral metabolite pattern observed by proton magnetic resonance spectroscopy (MRS).[2][3]

A positive history of Alcohol use and viral Hepatitis is suggestive of HE. The most common symptoms of Hepatic encephalopathy include:

History

Patients with Hepatic Encephalopathy may have a positive history of:

  • Viral hepatitis
  • Chronic alcohol use
  • History of drug and toxin use

Common Symptoms

Common symptoms of hepatic encephalopathy include:

  • Memory impairment
  • Personality changes
  • Coma
  • Jaundice


Hepatic encephalopathy (HE) is a common problem in liver cirrhosis and is associated with typical changes of cerebral metabolite pattern observed by proton magnetic resonance spectroscopy (MRS).[2]



























































































Hepatic encephalopathy (HE) is a common problem in liver cirrhosis and is associated with typical changes of cerebral metabolite pattern observed by proton magnetic resonance spectroscopy (MRS).

Less Common Symptoms

Less common symptoms of [disease name] include

  • [Symptom 2]
  • [Symptom 3]

References

  1. Schulz C, Schütte K, Vilchez-Vargas R, Vasapolli R, Malfertheiner P (November 2018). "Long-Term Effect of Rifaximin with and without Lactulose on the Active Bacterial Assemblages in the Proximal Small Bowel and Faeces in Patients with Minimal Hepatic Encephalopathy". Dig Dis: 1–9. doi:10.1159/000494216. PMID 30428474.
  2. 2.0 2.1 . PMID 30427626. Missing or empty |title= (help)
  3. Rimar D, Kruzel-Davila E, Dori G, Baron E, Bitterman H (April 2007). "Hyperammonemic coma--barking up the wrong tree". J Gen Intern Med. 22 (4): 549–52. doi:10.1007/s11606-007-0131-6. PMC 1829435. PMID 17372808.
  4. Shawcross DL, Dunk AA, Jalan R, Kircheis G, de Knegt RJ, Laleman W, Ramage JK, Wedemeyer H, Morgan IE (February 2016). "How to diagnose and manage hepatic encephalopathy: a consensus statement on roles and responsibilities beyond the liver specialist". Eur J Gastroenterol Hepatol. 28 (2): 146–52. doi:10.1097/MEG.0000000000000529. PMC 4885589. PMID 26600154.

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