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Overview

The majority of patients with Hepatic encephalopathy are asymptomatic.[1]

OR

The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History and Symptoms

Hepatic encephalopathy or portosystemic encephalopathy is a syndrome of largely reversible impairment of brain function occurring in patients with acute or chronic liver failure or when the liver is bypassed by portosystemic shunts.[2]

  • The hallmark of Hepatic Encephalopathy is . A positive history of Alcohol use and Viral Hepatitis is suggestive of Hepatitis. The most common symptoms of Hepatic encephalopathy include cognitive impairment, personality changes and change in consciousness. *Symptoms of Hepatic Encephalopathy include cognitive impairment, personality changes , and coma.

History

Patients with Hepatic Encephalopathy may have a positive history of:

  • Viral Hepatitis
  • Chronic alcohol use
  • History of drug and toxin use


  • [History finding 2]
  • [History finding 3]

Common Symptoms

Common symptoms of hepatic encephalopathy include:[3]


  • Memory impairment
  • Personality changes
  • Coma
  • Jaundice




















































































































































































































































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Z Gastroenterol. 2005 Apr;43(4):373-8.

[Detection of subclinical and overt hepatic encephalopathy and treatment control after L-ornithine-L-aspartate medication by magnetic resonance spectroscopy ((1)H-MRS)].

[Article in German]

Hass HG1, Nägele T, Seeger U, Hösl F, Gregor M, Kaiser S.


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Hepatic encephalopathy (HE) is a common problem in liver cirrhosis and is associated with typical changes of cerebral metabolite pattern observed by proton magnetic resonance spectroscopy (MRS).


























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Proton magnetic resonance spectroscopy (1H-MRS) findings for the brain in patients with liver cirrhosis reflect the hepatic functional reserve. [Am J Gastroenterol. 1999]




Cerebral abnormalities in patients with cirrhosis detected by proton magnetic resonance spectroscopy and magnetic resonance imaging. [Hepatology. 1997]




Clinical correlation of neuropsychological tests with 1H magnetic resonance spectroscopy in hepatic encephalopathy. [Psychosom Med. 1998]




Review Cerebral changes in hepatic encephalopathy. [J Gastroenterol Hepatol. 1998]




Review A critical analysis of studies assessing L-ornithine-L-aspartate (LOLA) in hepatic encephalopathy treatment. [Arq Gastroenterol. 2009]




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Less Common Symptoms

Less common symptoms of [disease name] include

  • [Symptom 2]
  • [Symptom 3]

References

  1. Jeong JH, Kim DK, Lee NS, Jeong YG, Kim HW, Kim JS, Han SY (2018). "Neuroprotective Effect of Nortriptyline in Overt Hepatic Encephalopathy Through Attenuation of Mitochondrial Dysfunction". ASN Neuro. 10: 1759091418810583. doi:10.1177/1759091418810583. PMID 30428281.
  2. Schulz C, Schütte K, Vilchez-Vargas R, Vasapolli R, Malfertheiner P (November 2018). "Long-Term Effect of Rifaximin with and without Lactulose on the Active Bacterial Assemblages in the Proximal Small Bowel and Faeces in Patients with Minimal Hepatic Encephalopathy". Dig Dis: 1–9. doi:10.1159/000494216. PMID 30428474.
  3. . PMID 30427626. Missing or empty |title= (help)

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