Sandbox:Shalinder

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shalinder Singh, M.B.B.S.[2]

Overview

The majority of patients with [disease name] are asymptomatic.

OR

The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History and Symptoms

History

Patients with atopic dermatitis may have a positive history of:[1]

  • cutaneous hyper-reactivity to diverse environmental stimuli:
    • exposure to food and inhalant allergens
    • changes in physical environment (including humidity, pollution etc)
    • irritants
    • microbial infection
    • stress
  • personal or family history of type I hypersensitivity
  • asthma
  • allergic rhinitis

Common Symptoms

Common symptoms of atopic dermatitis include:[2]

  • Pruritus
  • Chronic or relapsing dermatitis
  • Distribution of rash on:
    • Facial and extensor surfaces in infants and young children
    • Flexure lichenification in older children and adults
  • Personal or family history of atopy (asthma, allergic rhinitis, atopic dermatitis)

Less Common Symptoms

Less common symptoms of atopic dermatitis include:[3]

  • Facial pallor/facial erythema
  • Xerosis (especially in winter)
  • Nonspecific dermatitis of the hands and feet
  • Food intolerance
  • Itch when sweating

References

  1. Leung DY (June 2013). "New insights into atopic dermatitis: role of skin barrier and immune dysregulation". Allergol Int. 62 (2): 151–61. doi:10.2332/allergolint.13-RAI-0564. PMID 23712284.
  2. Deleuran, M.; Vestergaard, C. (2014). "Clinical heterogeneity and differential diagnosis of atopic dermatitis". British Journal of Dermatology. 170: 2–6. doi:10.1111/bjd.12933. ISSN 0007-0963.
  3. Rudikoff D, Lebwohl M (June 1998). "Atopic dermatitis". Lancet. 351 (9117): 1715–21. doi:10.1016/S0140-6736(97)12082-7. PMID 9734903.

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