Sandbox:MDS: Difference between revisions

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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Refractory anemia with ring sideroblasts (RARS)'''|| style="padding: 5px 5px; background: #F5F5F5;"|
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''Refractory anemia with ring sideroblasts (RARS)'''|
| style="padding: 5px 5px; background: #F5F5F5;"|
:* Less than 5% myeloblasts in the bone marrow, but distinguished by the presence of 15% or greater red cell precursors in the marrow being abnormal iron-stuffed cells called ringed sideroblasts.
:* Less than 5% myeloblasts in the bone marrow, but distinguished by the presence of 15% or greater red cell precursors in the marrow being abnormal iron-stuffed cells called ringed sideroblasts.


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! style="background: #4479BA; width: 250px; color: #FFFFFF;"|'''Old system'''
! style="background: #4479BA; width: 200px; color: #FFFFFF;"|'''Old system'''


! style="background: #4479BA; width: 600px; color: #FFFFFF;"|'''New system'''
! style="background: #4479BA; width: 200px; color: #FFFFFF;"|'''New system'''


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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia]]'''|| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia]]'''|
:*Refractory cytopenia with unilineage dysplasia
| style="padding: 5px 5px; background: #F5F5F5;" align=center |
 
Refractory cytopenia with unilineage dysplasia
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia with ringed sideroblasts]]'''
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia with ringed sideroblasts]]'''|| style="padding: 5px 5px; background: #F5F5F5;"|
| style="padding: 5px 5px; background: #F5F5F5;" align=center |
:*Refractory anemia with ring sideroblasts
Refractory anemia with ring sideroblasts
 
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | || style="padding: 5px 5px; background: #F5F5F5;"|:*Refractory cytopenia with multilineage dysplasia
|style="padding: 5px 5px; background: #F5F5F5;" align=center |
 
Refractory cytopenia with multilineage dysplasia
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia with excess blasts]]'''
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia with excess blasts]]'''|| style="padding: 5px 5px; background: #F5F5F5;"|
| style="padding: 5px 5px; background: #F5F5F5;" align=center |
:*Refractory anemias with excess blasts I and II
Refractory anemias with excess blasts I and II
 
 
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia with excess blasts in transformation]] I–IV '''|
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Refractory anemia with excess blasts in transformation]] I–IV '''|| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" align=center |
:*5q - syndrome
5q - syndrome
 
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Chronic myelomonocytic leukemia]]'''|
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center | '''[[Chronic myelomonocytic leukemia]]'''|| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" align=center |
:*Myelodysplastic-myeloproliferative overlap syndromes
Myelodysplastic-myeloproliferative overlap syndromes
 
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| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center |
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center |
| style="padding: 5px 5px; background: #F5F5F5;"|
| style="padding: 5px 5px; background: #F5F5F5;" align=center |
:*Refractory cytopenia of childhood  
Refractory cytopenia of childhood
 
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|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center |
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align=center |
| style="padding: 5px 5px; background: #F5F5F5;" |
| style="padding: 5px 5px; background: #F5F5F5;" align=center |
:*Unclassifiable myelodysplastic syndrome
Unclassifiable myelodysplastic syndrome
 
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Revision as of 15:02, 8 December 2015

Name Description
Refractory anemia
  • Less than 5% primitive blood cells (myeloblasts) in the bone marrow and pathological abnormalities primarily seen in red cell precursors.
Refractory anemia with ring sideroblasts (RARS)|
  • Less than 5% myeloblasts in the bone marrow, but distinguished by the presence of 15% or greater red cell precursors in the marrow being abnormal iron-stuffed cells called ringed sideroblasts.
Refractory anemia with excess blasts (RAEB)
  • 5-20% myeloblasts in the marrow.
Refractory anemia with excess blasts in transformation (RAEB-T)
  • 21-30% myeloblasts in the marrow (>30% blasts is defined as acute myeloid leukemia).
Chronic myelomonocytic leukemia (CMML)
  • Less than 20% myeloblasts in the bone marrow and greater than 1*109/L monocytes in peripheral blood.



Old system New system
Refractory anemia|

Refractory cytopenia with unilineage dysplasia

Refractory anemia with ringed sideroblasts

Refractory anemia with ring sideroblasts

Refractory cytopenia with multilineage dysplasia

Refractory anemia with excess blasts

Refractory anemias with excess blasts I and II

Refractory anemia with excess blasts in transformation I–IV |

5q - syndrome

Chronic myelomonocytic leukemia|

Myelodysplastic-myeloproliferative overlap syndromes

Refractory cytopenia of childhood

Unclassifiable myelodysplastic syndrome