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<!--THIS IS THE 1ST BUTTON THAT TRIGGERS THE 1ST BOX NAMED TABLE01.-->
<!--THIS IS THE 1ST BUTTON THAT TRIGGERS THE 1ST BOX NAMED TABLE01.-->
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<font color="#FFF">
<font color="#FFF">
&nbsp;&nbsp;▸&nbsp;&nbsp;'''Methicillin-sensitive S.aureus'''
&nbsp;&nbsp;▸&nbsp;&nbsp;'''Methicillin-sensitive S.aureus'''
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<!--THIS IS THE 2ND BUTTON THAT TRIGGERS THE 2ND BOX NAMED TABLE02.-->
<!--THIS IS THE 2ND BUTTON THAT TRIGGERS THE 2ND BOX NAMED TABLE02.-->
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<div class="mw-customtoggle-table05" style="cursor: pointer; border-radius: 0 0 0 0; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 225px; background: #4479BA;">
<font color="#FFF">
<font color="#FFF">
&nbsp;&nbsp;▸&nbsp;&nbsp;'''Methicillin-resistant S.aureus'''  
&nbsp;&nbsp;▸&nbsp;&nbsp;'''Methicillin-resistant S.aureus'''  
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<!--THIS IS THE 3RD BUTTON THAT TRIGGERS THE 3RD BOX NAMED TABLE03.-->
<!--THIS IS THE 3RD BUTTON THAT TRIGGERS THE 3RD BOX NAMED TABLE03.-->
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<div class="mw-customtoggle-table06" style="cursor: pointer; border-radius: 0 0 0 0; border: solid 1px #20538D; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5); box-shadow: inset 0 1px 1px rgba(255, 255, 255, 0.5), 0 1px 1px rgba(0, 0, 0, 0.5); height: 30px; line-height: 30px; width: 225px; background: #4479BA;">
<font color="#FFF">
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&nbsp;&nbsp;▸&nbsp;&nbsp;'''Salmonella; GN bacilli''' </font>
&nbsp;&nbsp;▸&nbsp;&nbsp;'''Salmonella; GN bacilli''' </font>
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Revision as of 16:06, 20 May 2014

Hematogenous Osteomyelitis

Empiric Therapy

▸ Click on the following categories to expand treatment regimens.

Age

  ▸  Newborn (<4 months)

  ▸  Children (>4 months) - Adults

  ▸  Adult (>21 years)

Staph aureus, gram-negative bacilli, group B strept
Preferred Regimen
Vancomycin 40 mg divided q6-8 hours
PLUS
Ceftazidime 50 mg IV q8h
OR
Cefepime 150 mg IV q8h
Alternative Regimen
Nafcillin
OR
Oxcacillin 37 mg q6h
PLUS
Ceftazidime 2 gm IV q8h
OR
Cefepime 2 gm IV q12h
Staph aureus, group A strept, gram-negative bacilli
Preferred Regimen
Vancomycin 40 mg divided q6-8 hours
PLUS
Ceftazidime 50 mg IV q8h
OR
Cefepime 150 mg IV q8h
Alternative Regimen
Nafcillin
OR
Oxcacillin 37 mg q6h
PLUS
Ceftazidime 2 gm IV q8h
OR
Cefepime 2 gm IV q12h
Staph aureus (most common)
Preferred Regimen
Vancomycin 1 gm IV q12h, if over 100 kg, 1.5 gm IV q12h
Alternative Regimen
Nafcillin 2 gm IV q4h
OR
Oxacillin 2 gm IV q4h














Specific Therapy

▸ Click on the following categories to expand treatment regimens.

Specific Etiology

  ▸  Methicillin-sensitive S.aureus

  ▸  Methicillin-resistant S.aureus

  ▸  Salmonella; GN bacilli

MSSA
Preferred Regimen
Nafcillin 2 gm IV q4h
OR
Oxacillin 2 gm IV q4h
OR
Cefazolin IV q8h
Alternative Regimen
Vancomycin 1 gm q12h IV; if over 100 kg, 1.5 gm IV q12h
MRSA
Preferred Regimen
Vancomycin 1 gm q12h IV
Alternative Regimen
Linezolid 600 mg q12h IV/po
±
Rifampin 300 mg po/IV bid
Salmonella (Gram-negative bacilli)
Preferred Regimen
Ciprofloxacin 400 mg IV q12h
Alternative Regimen
Levofloxacin 750 mg IV q24h