Sandbox/osteo: Difference between revisions

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| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Preferred Regimen
| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Preferred Regimen
|-
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Vancomycin]] 40 mg divided q6-8 hours''''' <SMALL>(trough 15—20 μg/mL)</SMALL>
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Vancomycin]] 40 mg divided q6-8 hours'''''
|-
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | PLUS
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | PLUS
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| valign=top |
| valign=top |
{| style="float: left; cellpadding=0; cellspacing= 0; width: 400px;"
{| style="float: left; cellpadding=0; cellspacing= 0; width: 400px;"
! style="height: 30px; line-height: 30px; background: #4479BA; border: 0px; font-size: 100%; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5);" align=center | {{fontcolor|#FFF|Gram-Positive Cocci in Pairs}}
! style="height: 30px; line-height: 30px; background: #4479BA; border: 0px; font-size: 100%; text-shadow: 0 -1px 0 rgba(0, 0, 0, 0.5);" align=center | {{fontcolor|#FFF|}}
|-
|-
| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Preferred Regimen
| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Preferred Regimen
|-
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Ampicillin]] 2 g IV q4h'''''<BR> OR <BR> ▸ '''''[[Penicillin G]] 4 MU IV q4h'''''
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Vancomycin]] 40 mg divided q6-8 hours'''''
|-
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | PLUS
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | PLUS
|-
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Gentamicin]] 1.7 mg/kg IV q8h'''''
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Ceftazidime]] 50 mg IV q8h'''''<BR> OR <BR> ▸ '''''[[Cefepime]] 150 mg IV q8h'''''
|-
|-
| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Alternative Regimen
| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Alternative Regimen
|-
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Cefotaxime]] 2 g IV q4—6h'''''<BR> OR <BR> ▸ '''''[[Ceftriaxone]] 2 g IV q12h'''''
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Nafcillin]]''''' <br> OR <br> ▸ '''''[[Oxcacillin]] 37mg q6h'''''
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | PLUS
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Ceftazidime]] 2 gm IV q8h''''' <br> OR <br> '''''[[Cefepime]] 2 gm IV q12h'''''
|-
|-
|}
|}
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| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Preferred Regimen
| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Preferred Regimen
|-
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Ampicillin]] 2 g IV q4h'''''<BR> OR <BR> ▸ '''''[[Penicillin G]] 4 MU IV q4h'''''
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Vancomycin]] 1 gm IV q12h, if over 100 kg, 1.5 gm IV q12h'''''
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | PLUS
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Gentamicin]] 1.7 mg/kg IV q8h'''''
|-
|-
| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Alternative Regimen
| style="padding: 0 5px; font-size: 90%; background: #F5F5F5; font-weight: bold; font-style: italic;" align=center | Alternative Regimen
|-
|-
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[TMP/SMZ]] 5 mg/kg IV q6—12h''''' <SMALL>(TMP component)</SMALL><BR> OR <BR> ▸ '''''[[Meropenem]] 2 g IV q8h'''''
| style="font-size: 90%; padding: 0 5px; background: #DCDCDC" align=left | ▸ '''''[[Nafcillin]] 2 gm IV q4h''''' <br> OR <br> ▸ '''''[[Oxacillin]] 2 gm IV q4h'''''
|-
|-
|}
|}
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Preferred regimen
Vancomycin 40 mg divided q6-8 hours
PLUS
[[Ceftazidime]] 50 mg IV q8h <br> OR <br> [[Cefepime]] 150 mg IV q8h
Alternative regimen
Nafcillin or oxcacillin 37mg q6h
PLUS
Ceftazidime 2 gm IV q8h OR Cefepime 2 gm IV q12h
Preferred regimen
Vancomycin 40 mg divided q6-8 hours
PLUS
Ceftazidime 50 mg IV q8h OR Cefepime 150 mg IV q8h
Alternative regimen
Nafcillin or oxcacillin37mg q6h
PLUS
Ceftazidime 2 gm IV q8h OR Cefepime 2 gm IV q12h


Preferred regimen
Preferred regimen
Vancomycin 1 gm IV q12h, if over 100 kg, 1.5 gm IV q12h
Vancomycin 1 gm IV q12h, if over 100 kg, 1.5 gm IV q12h
Alternative regimen
Alternative regimen
Nafcillin or oxacillin 2 gm IV q4h
Nafcillin 2 gm IV q4h or oxacillin 2 gm IV q4h

Revision as of 15:24, 20 May 2014

Hematogenous Osteomyelitis

Empiric Therapy

▸ Click on the following categories to expand treatment regimens.

Age

  ▸  Newborn (<4 months)

  ▸  Children (>4 months) - Adults

  ▸  Adult (>21 years)

Gram-Positive Cocci in Chains
Preferred Regimen
▸ Vancomycin 40 mg divided q6-8 hours
PLUS
▸ Ceftazidime 50 mg IV q8h
OR
▸ Cefepime 150 mg IV q8h
Alternative Regimen
▸ Nafcillin
OR
▸ Oxcacillin 37mg q6h
PLUS
▸ Ceftazidime 2 gm IV q8h
OR
Cefepime 2 gm IV q12h
Preferred Regimen
▸ Vancomycin 40 mg divided q6-8 hours
PLUS
▸ Ceftazidime 50 mg IV q8h
OR
▸ Cefepime 150 mg IV q8h
Alternative Regimen
▸ Nafcillin
OR
▸ Oxcacillin 37mg q6h
PLUS
▸ Ceftazidime 2 gm IV q8h
OR
Cefepime 2 gm IV q12h
Gram-Positive (Cocco-)Bacilli
Preferred Regimen
▸ Vancomycin 1 gm IV q12h, if over 100 kg, 1.5 gm IV q12h
Alternative Regimen
▸ Nafcillin 2 gm IV q4h
OR
▸ Oxacillin 2 gm IV q4h





Preferred regimen Vancomycin 1 gm IV q12h, if over 100 kg, 1.5 gm IV q12h Alternative regimen Nafcillin 2 gm IV q4h or oxacillin 2 gm IV q4h

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