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==Natural History==
==Natural History==
Salmonellosis commonly occurs after 6 to 72 hours afters ingestion of the contaminated food. The inoculum responsible for the disease is often greater 50000 bacteria.<ref name="pmid17146467">{{cite journal| author=Coburn B, Grassl GA, Finlay BB| title=Salmonella, the host and disease: a brief review. | journal=Immunol Cell Biol | year= 2007 | volume= 85 | issue= 2 | pages= 112-8 | pmid=17146467 | doi=10.1038/sj.icb.7100007 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17146467  }} </ref> Symptoms have an acute onset, and include abdominal pain, and diarrhea.
Salmonellosis commonly occurs after 6 to 72 hours afters ingestion of the contaminated food. The inoculum responsible for the disease is often greater 50000 bacteria.<ref name="pmid17146467">{{cite journal| author=Coburn B, Grassl GA, Finlay BB| title=Salmonella, the host and disease: a brief review. | journal=Immunol Cell Biol | year= 2007 | volume= 85 | issue= 2 | pages= 112-8 | pmid=17146467 | doi=10.1038/sj.icb.7100007 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17146467  }} </ref> [[Symptoms]] include acute onset of [[nausea]], [[vomiting]], crampy [[abdominal pain]], and [[diarrhea]], that may be bloody.


==Complications==
==Complications==

Revision as of 12:30, 21 August 2014

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2] Jolanta Marszalek, M.D. [3]

Overview

There are an estimated 400 fatal cases each year; a few cases are complicated by chronic arthritis.Infection is through contaminated food, water, or contact with infected animals.

Natural History

Salmonellosis commonly occurs after 6 to 72 hours afters ingestion of the contaminated food. The inoculum responsible for the disease is often greater 50000 bacteria.[1] Symptoms include acute onset of nausea, vomiting, crampy abdominal pain, and diarrhea, that may be bloody.

Complications

Persons with diarrhea usually recover completely, although it may be several months before their bowel habits are entirely normal. A small number of persons with Salmonella develop pain in their joints, irritation of the eyes, and painful urination. This is called Reiter's syndrome. It can last for months or years, and can lead to chronic arthritis which is difficult to treat. Antibiotic treatment does not make a difference in whether or not the person develops arthritis.

Prognosis

Persons with diarrhea usually recover completely, although it may be several months before their bowel habits are entirely normal. A small number of persons who are infected with Salmonella, will go on to develop pains in their joints, irritation of the eyes, and painful urination. This is called Reiter's syndrome. It can last for months or years, and can lead to chronic arthritis which is difficult to treat. Antibiotic treatment does not make a difference in whether or not the person later develops arthritis.[2]

References

  1. Coburn B, Grassl GA, Finlay BB (2007). "Salmonella, the host and disease: a brief review". Immunol Cell Biol. 85 (2): 112–8. doi:10.1038/sj.icb.7100007. PMID 17146467.
  2. http://www.cdc.gov/ncidod/dbmd/diseaseinfo/salmonellosis_g.htm


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