SYT3: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Synaptotagmin-3''' is a [[protein]] that in humans is encoded by the ''SYT3'' [[gene]].<ref name="pmid7749232">{{cite journal | vauthors = Jones JM, Popma SJ, Mizuta M, Seino S, Meisler MH | title = Synaptotagmin genes on mouse chromosomes 1, 7, and 10 and human chromosome 19 | journal = Mammalian Genome | volume = 6 | issue = 3 | pages = 212–3 | date = March 1995 | pmid = 7749232 | pmc = | doi = 10.1007/BF00293017 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SYT3 synaptotagmin III| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84258| accessdate = }}</ref>
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== References ==
{{GNF_Protein_box
{{reflist}}
| image = PBB_Protein_SYT3_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1dqv.
| PDB = {{PDB2|1dqv}}
| Name = Synaptotagmin III
| HGNCid = 11511
| Symbol = SYT3
| AltSymbols =; DKFZp761O132; SytIII
| OMIM = 600327
| ECnumber = 
| Homologene = 9617
| MGIid = 99665
| GeneAtlas_image1 = PBB_GE_SYT3_gnf1h00687_at_tn.png
| GeneAtlas_image2 = PBB_GE_SYT3_gnf1h05716_s_at_tn.png
| Function = {{GNF_GO|id=GO:0005215 |text = transporter activity}} {{GNF_GO|id=GO:0005509 |text = calcium ion binding}}
| Component = {{GNF_GO|id=GO:0005768 |text = endosome}} {{GNF_GO|id=GO:0008021 |text = synaptic vesicle}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}} {{GNF_GO|id=GO:0045202 |text = synapse}}
| Process = {{GNF_GO|id=GO:0006810 |text = transport}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 84258
    | Hs_Ensembl = 
    | Hs_RefseqProtein = NP_115674
    | Hs_RefseqmRNA = NM_032298
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 
    | Hs_GenLoc_start = 
    | Hs_GenLoc_end = 
    | Hs_Uniprot = 
    | Mm_EntrezGene = 20981
    | Mm_Ensembl = ENSMUSG00000030731
    | Mm_RefseqmRNA = NM_016663
    | Mm_RefseqProtein = NP_057872
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 44252863
    | Mm_GenLoc_end = 44268071
    | Mm_Uniprot = Q9JM86
  }}
}}
'''Synaptotagmin III''', also known as '''SYT3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SYT3 synaptotagmin III| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84258| accessdate = }}</ref>


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== Further reading ==
{{PBB_Summary
| section_title =
| summary_text =
}}
 
==References==
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Li C, Ullrich B, Zhang JZ, Anderson RG, Brose N, Südhof TC | title = Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins | journal = Nature | volume = 375 | issue = 6532 | pages = 594–9 | date = June 1995 | pmid = 7791877 | doi = 10.1038/375594a0 }}
| citations =
* {{cite journal | vauthors = Fukuda M, Kanno E, Mikoshiba K | title = Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X | journal = The Journal of Biological Chemistry | volume = 274 | issue = 44 | pages = 31421–7 | date = October 1999 | pmid = 10531343 | doi = 10.1074/jbc.274.44.31421 }}
*{{cite journal  | author=Jones JM, Popma SJ, Mizuta M, ''et al.'' |title=Synaptotagmin genes on mouse chromosomes 1, 7, and 10 and human chromosome 19. |journal=Mamm. Genome |volume=6 |issue= 3 |pages= 212-3 |year= 1995 |pmid= 7749232 |doi=  }}
* {{cite journal | vauthors = Gerona RR, Larsen EC, Kowalchyk JA, Martin TF | title = The C terminus of SNAP25 is essential for Ca(2+)-dependent binding of synaptotagmin to SNARE complexes | journal = The Journal of Biological Chemistry | volume = 275 | issue = 9 | pages = 6328–36 | date = March 2000 | pmid = 10692432 | doi = 10.1074/jbc.275.9.6328 }}
*{{cite journal | author=Li C, Ullrich B, Zhang JZ, ''et al.'' |title=Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. |journal=Nature |volume=375 |issue= 6532 |pages= 594-9 |year= 1995 |pmid= 7791877 |doi= 10.1038/375594a0 }}
* {{cite journal | vauthors = Mizutani A, Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K | title = SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms | journal = The Journal of Biological Chemistry | volume = 275 | issue = 13 | pages = 9823–31 | date = March 2000 | pmid = 10734137 | doi = 10.1074/jbc.275.13.9823 }}
*{{cite journal | author=Fukuda M, Kanno E, Mikoshiba K |title=Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X. |journal=J. Biol. Chem. |volume=274 |issue= 44 |pages= 31421-7 |year= 1999 |pmid= 10531343 |doi= }}
* {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA cloning using in vitro site-specific recombination | journal = Genome Research | volume = 10 | issue = 11 | pages = 1788–95 | date = November 2000 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }}
*{{cite journal | author=Gerona RR, Larsen EC, Kowalchyk JA, Martin TF |title=The C terminus of SNAP25 is essential for Ca(2+)-dependent binding of synaptotagmin to SNARE complexes. |journal=J. Biol. Chem. |volume=275 |issue= 9 |pages= 6328-36 |year= 2000 |pmid= 10692432 |doi= }}
* {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Research | volume = 11 | issue = 3 | pages = 422–35 | date = March 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
*{{cite journal | author=Mizutani A, Fukuda M, Ibata K, ''et al.'' |title=SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms. |journal=J. Biol. Chem. |volume=275 |issue= 13 |pages= 9823-31 |year= 2000 |pmid= 10734137 |doi= }}
* {{cite journal | vauthors = Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S | title = Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing | journal = EMBO Reports | volume = 1 | issue = 3 | pages = 287–92 | date = September 2000 | pmid = 11256614 | pmc = 1083732 | doi = 10.1093/embo-reports/kvd058 }}
*{{cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788-95 |year= 2001 |pmid= 11076863 |doi= }}
* {{cite journal | vauthors = Craxton M | title = Genomic analysis of synaptotagmin genes | journal = Genomics | volume = 77 | issue = 1-2 | pages = 43–9 | date = September 2001 | pmid = 11543631 | doi = 10.1006/geno.2001.6619 }}
*{{cite journal | author=Wiemann S, Weil B, Wellenreuther R, ''et al.'' |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422-35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701 }}
* {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | title = From ORFeome to biology: a functional genomics pipeline | journal = Genome Research | volume = 14 | issue = 10B | pages = 2136–44 | date = October 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }}
*{{cite journal | author=Simpson JC, Wellenreuther R, Poustka A, ''et al.'' |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287-92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058 }}
* {{cite journal|authorlink30=Huda Zoghbi | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = October 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
*{{cite journal | author=Craxton M |title=Genomic analysis of synaptotagmin genes. |journal=Genomics |volume=77 |issue= 1-2 |pages= 43-9 |year= 2001 |pmid= 11543631 |doi= 10.1006/geno.2001.6619 }}
* {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | title = The LIFEdb database in 2006 | journal = Nucleic Acids Research | volume = 34 | issue = Database issue | pages = D415-8 | date = January 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Wiemann S, Arlt D, Huber W, ''et al.'' |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136-44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Mehrle A, Rosenfelder H, Schupp I, ''et al.'' |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415-8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139 }}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=84258}}
{{Vesicular transport proteins}}


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Latest revision as of 16:25, 8 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Synaptotagmin-3 is a protein that in humans is encoded by the SYT3 gene.[1][2]

References

  1. ↑ Jones JM, Popma SJ, Mizuta M, Seino S, Meisler MH (March 1995). "Synaptotagmin genes on mouse chromosomes 1, 7, and 10 and human chromosome 19". Mammalian Genome. 6 (3): 212–3. doi:10.1007/BF00293017. PMID 7749232.
  2. ↑ "Entrez Gene: SYT3 synaptotagmin III".

Further reading

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