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'''DO NOT EDIT THESE GUIDELINES'''. You can make comments regarding the guidelines in the discussion section.
'''DO NOT EDIT THESE GUIDELINES'''. You can make comments regarding the guidelines in the discussion section.
==[[Interpreting the ACC / AHA Guidelines]]==
==[[ST Elevation Myocardial Infarction Oxygen Therapy|Oxygen]]==
==[[ST Elevation Myocardial Infarction Nitrate Therapy|Nitrates]]==
==[[ST Elevation Myocardial Infarction Analgesic Therapy|Analgesics]]==
==[[ST Elevation Myocardial Infarction Aspirin Therapy|Aspirin]]==
==[[ST Elevation Myocardial Infarction Beta Blocker Therapy|Beta Blockers]]==
==[[ST Elevation Myocardial Infarction Reperfusion Therapy|Reperfusion Therapy (Overview of Fibrinolysis and Primary PCI)]]==
===[[ST Elevation Myocardial Infarction Fibrinolytic Therapy|Fibrinolysis]]===
===[[ST Elevation Myocardial Infarction Primary Percutaneous Coronary Intervention|Primary PCI]]===
===[[ST Elevation Myocardial Infarction Percutaneous Coronary Intervention Following Fibrinolytic Administration|Adjunctive and Rescue PCI]]===
===[[ST Elevation Myocardial Infarction Coronary Artery Bypass Grafting|CABG]]===
===[[ST Elevation Myocardial Infarction Management of Patients Who Were Not Reperfused|Management of Patients Who Were Not Reperfused]]===
===[[ST Elevation Myocardial Infarction Assessing Success of Reperfusion|Assessing Success of Reperfusion]]===
==Antithrombin Therapy (Overview) ==
=== [[ST Elevation Myocardial Infarction Unfractionated Heparin (UFH) Therapy|Unfractionated Heparin (UFH) Therapy]]===
===[[ST Elevation Myocardial Infarction Low Molecular Weight Heparinoid Therapy| Low Molecular Weight Heparinoid Therapy]]===
===[[ST Elevation Myocardial Infarction Direct Thrombin Inhibitor Therapy| Direct Thrombin Inhibitor Therapy]]===
==Antiplatelet Agents==
===[[ST Elevation Myocardial Infarction Aspirin Therapy|Aspirin]]===
===[[ST Elevation Myocardial Infarction Thienopyridine Therapy|Thienopyridine Therapy]]===
===[[ST Elevation Myocardial Infarction Glycoprotein IIbIIIa Inhibition|Glycoprotein IIbIIIa Inhibition]] ===
----
== [[ST Elevation Myocardial Infarction Inhibition of the Renin-Angiotensin-Aldosterone System|Inhibition of the Renin-Angiotensin-Aldosterone System]] ==
==[[ST Elevation Myocardial Infarction Magnesium Therapy|Magnesium Therapy]]==
==[[ST Elevation Myocardial Infarction Glucose Control|Glucose Control]]==
==[[ST Elevation Myocardial Infarction Calcium Channel Blocker Therapy|Calcium Channel Blocker Therapy]] ==
==See also==
* [[acute coronary syndrome]]
* [[angina pectoris|angina]]
* [[Cardiac arrest]]
* [[coronary thrombosis]]
* [[Hibernating myocardium]]
* [[Stunned myocardium]]
* [[Ventricular remodeling]]


==References==
==References==
Line 98: Line 38:
==External links==
==External links==
* [http://www.themdtv.org The MD TV: Comments on Hot Topics, State of the Art Presentations in Cardiovascular Medicine, Expert Reviews on Cardiovascular Research]
* [http://www.themdtv.org The MD TV: Comments on Hot Topics, State of the Art Presentations in Cardiovascular Medicine, Expert Reviews on Cardiovascular Research]
* [http://www.clinicaltrialresults.org Clinical Trial Results: An up to dated resource of Cardiovascular Research]
* [http://www.clinicaltrialresults.org Clinical Trial Results: An up to date resource of Cardiovascular Research]
* [http://hp2010.nhlbihin.net/atpiii/calculator.asp?usertype=pub Risk Assessment Tool for Estimating Your 10-year Risk of Having a Heart Attack] - based on information of the [[Framingham Heart Study]], from the United States [[National Heart, Lung and Blood Institute]]
* [http://hp2010.nhlbihin.net/atpiii/calculator.asp?usertype=pub Risk Assessment Tool for Estimating Your 10-year Risk of Having a Heart Attack] - based on information of the [[Framingham Heart Study]], from the United States [[National Heart, Lung and Blood Institute]]
* [http://www.nlm.nih.gov/medlineplus/heartattack.html Heart Attack] - overview of resources from [[MedlinePlus]].
* [http://www.nlm.nih.gov/medlineplus/heartattack.html Heart Attack] - overview of resources from [[MedlinePlus]].

Revision as of 01:58, 16 February 2009

Myocardial infarction
ICD-10 I21-I22
ICD-9 410
DiseasesDB 8664
MedlinePlus 000195
eMedicine med/1567  emerg/327 ped/2520

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Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Please Join in Editing This Page and Apply to be an Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [3] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

The goal of initial care is to restore epicardial artery patency as rapidly and fully as possible, and to reduce the risk of early vessel reocclusion. Other goals include reducing the risk of lethal ventricular arrhythmias and other complications as well as reducing myocardial oxygen demands to limit infarct size.

Overview of Initial Therapies

Initial therapies include oxygen, aspirin, nitroglycerin or glyceryl trinitrate (excluding though those patients with a right ventricular myocardial infarction) and analgesia (usually morphine). Morphine is the preferred analgesic agent due to its ability to reduce adrenergic drive and reduce preload (it is a venodilator). The antiplatelet agent aspirin has been associated with a reduction in mortality.[1]

Once the diagnosis of myocardial infarction is confirmed, additional pharmacologic agents may then be administered. These include beta blockers[2][3] and anticoagulation therapy (typically with an antithrombin)[4]

Wikidoc cites here the ACC / AHA Guidelines Based Therapy for ST Elevation MI [5]

DO NOT EDIT THESE GUIDELINES. You can make comments regarding the guidelines in the discussion section.

References

  1. "Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group". Lancet. 2 (8607): 349–60. 1988. PMID 2899772. Unknown parameter |month= ignored (help)
  2. "Randomised trial of intravenous atenolol among 16 027 cases of suspected acute myocardial infarction: ISIS-1. First International Study of Infarct Survival Collaborative Group". Lancet. 2 (8498): 57–66. 1986. PMID 2873379. Unknown parameter |month= ignored (help)
  3. "Comparison of invasive and conservative strategies after treatment with intravenous tissue plasminogen activator in acute myocardial infarction. Results of the thrombolysis in myocardial infarction (TIMI) phase II trial. The TIMI Study Group". N. Engl. J. Med. 320 (10): 618–27. 1989. PMID 2563896. Unknown parameter |month= ignored (help)
  4. Antman EM, Anbe DT, Armstrong PW; et al. (2004). "ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 1999 Guidelines for the Management of Patients With Acute Myocardial Infarction)". Circulation. 110 (5): 588–636. doi:10.1161/01.CIR.0000134791.68010.FA. PMID 15289388. Unknown parameter |month= ignored (help)
  5. Antman EM, Hand M, Armstrong PW; et al. (2008). "2007 Focused Update of the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines: developed in collaboration With the Canadian Cardiovascular Society endorsed by the American Academy of Family Physicians: 2007 Writing Group to Review New Evidence and Update the ACC/AHA 2004 Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction, Writing on Behalf of the 2004 Writing Committee". Circulation. 117 (2): 296–329. doi:10.1161/CIRCULATIONAHA.107.188209. PMID 18071078. Unknown parameter |month= ignored (help)

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