SSR2
| Signal sequence receptor, beta (translocon-associated protein beta) | |||||||||||
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| Identifiers | |||||||||||
| Symbols | SSR2 ; DKFZp686F19123; HSD25; TLAP; TRAPB | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 2369 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE SSR2 200652 at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
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| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
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Signal sequence receptor, beta (translocon-associated protein beta), also known as SSR2, is a human gene.[1]
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23.[1]
References
Further reading
- Tajima S, Lauffer L, Rath VL, Walter P (1986). "The signal recognition particle receptor is a complex that contains two distinct polypeptide chains". J. Cell Biol. 103 (4): 1167–78. PMID 3021779.
- Chinen K, Sudo K, Takahashi E, Nakamura Y (1995). "Isolation and mapping of the human beta-signal sequence receptor gene (SSR2)". Cytogenet. Cell Genet. 70 (3–4): 215–7. PMID 7789174.
- Hartmann E, Görlich D, Kostka S; et al. (1993). "A tetrameric complex of membrane proteins in the endoplasmic reticulum". Eur. J. Biochem. 214 (2): 375–81. PMID 7916687.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
- Bodescot M, Brison O (1994). "Cloning and sequence analysis of the beta subunit of the human translocon-associated protein". Biochim. Biophys. Acta. 1217 (1): 101–2. PMID 8286409.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
- Wang L, Dobberstein B (1999). "Oligomeric complexes involved in translocation of proteins across the membrane of the endoplasmic reticulum". FEBS Lett. 457 (3): 316–22. PMID 10471800.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nat. Biotechnol. 21 (6): 660–6. doi:10.1038/nbt827. PMID 12754519.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Suzuki Y, Yamashita R, Shirota M; et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMID 15342556.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
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