SNIP1: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Smad nuclear-interacting protein 1''' is a [[protein]] that in humans is encoded by the ''SNIP1'' [[gene]].<ref name="pmid10887155">{{cite journal | vauthors = Kim RH, Wang D, Tsang M, Martin J, Huff C, de Caestecker MP, Parks WT, Meng X, Lechleider RJ, Wang T, Roberts AB | title = A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction | journal = Genes Dev. | volume = 14 | issue = 13 | pages = 1605–16 | year = 2000 | pmid = 10887155 | pmc = 316742 | doi = 10.1101/gad.14.13.1605 }}</ref><ref name="pmid15378006">{{cite journal | vauthors = Roche KC, Wiechens N, Owen-Hughes T, Perkins ND | title = The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression | journal = Oncogene | volume = 23 | issue = 50 | pages = 8185–8195 | year = 2004 | pmid = 15378006 | pmc = | doi = 10.1038/sj.onc.1208025 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SNIP1 Smad nuclear interacting protein 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79753| accessdate = }}</ref>
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== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Smad nuclear interacting protein 1
| HGNCid = 30587
| Symbol = SNIP1
| AltSymbols =; FLJ12553; RP3-423B22.3; dJ423B22.2
| OMIM = 608241
| ECnumber = 
| Homologene = 41580
| MGIid = 2156003
| GeneAtlas_image1 = PBB_GE_SNIP1_219409_at_tn.png
| Function =
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 79753
    | Hs_Ensembl = ENSG00000163877
    | Hs_RefseqProtein = NP_078976
    | Hs_RefseqmRNA = NM_024700
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 1
    | Hs_GenLoc_start = 37774729
    | Hs_GenLoc_end = 37792490
    | Hs_Uniprot = Q8TAD8
    | Mm_EntrezGene = 76793
    | Mm_Ensembl = ENSMUSG00000050213
    | Mm_RefseqmRNA = NM_175246
    | Mm_RefseqProtein = NP_780455
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 4
    | Mm_GenLoc_start = 124568997
    | Mm_GenLoc_end = 124576339
    | Mm_Uniprot = Q8BIZ6
  }}
}}
'''Smad nuclear interacting protein 1''', also known as '''SNIP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SNIP1 Smad nuclear interacting protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79753| accessdate = }}</ref>


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SNIP1 has been shown to [[Protein-protein interaction|interact]] with [[EP300]].<ref name=pmid10887155 />
{{PBB_Summary
| section_title =  
| summary_text =
}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Kim RH, Flanders KC, Birkey Reffey S, Anderson LA, Duckett CS, Perkins ND, Roberts AB | title = SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators | journal = J. Biol. Chem. | volume = 276 | issue = 49 | pages = 46297–46304 | year = 2001 | pmid = 11567019 | doi = 10.1074/jbc.M103819200 }}
| citations =
* {{cite journal | vauthors = Lin Y, Martin J, Gruendler C, Farley J, Meng X, Li BY, Lechleider R, Huff C, Kim RH, Grasser WA, Paralkar V, Wang T | title = A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs) | journal = BMC Cell Biol. | volume = 3 | pages = 15 | year = 2002 | pmid = 12097147 | pmc = 117437 | doi = 10.1186/1471-2121-3-15 }}
*{{cite journal | author=Kim RH, Wang D, Tsang M, ''et al.'' |title=A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction. |journal=Genes Dev. |volume=14 |issue= 13 |pages= 1605-16 |year= 2000 |pmid= 10887155 |doi=  }}
* {{cite journal | vauthors = Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM | title = Functional proteomics mapping of a human signaling pathway | journal = Genome Res. | volume = 14 | issue = 7 | pages = 1324–1332 | year = 2004 | pmid = 15231748 | pmc = 442148 | doi = 10.1101/gr.2334104 }}
*{{cite journal  | author=Kim RH, Flanders KC, Birkey Reffey S, ''et al.'' |title=SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators. |journal=J. Biol. Chem. |volume=276 |issue= 49 |pages= 46297-304 |year= 2002 |pmid= 11567019 |doi= 10.1074/jbc.M103819200 }}
* {{cite journal | vauthors = Cui Q, Lim SK, Zhao B, Hoffmann FM | title = Selective inhibition of TGF-beta responsive genes by Smad-interacting peptide aptamers from FoxH1, Lef1 and CBP | journal = Oncogene | volume = 24 | issue = 24 | pages = 3864–3874 | year = 2005 | pmid = 15750622 | doi = 10.1038/sj.onc.1208556 }}
*{{cite journal | author=Lin Y, Martin J, Gruendler C, ''et al.'' |title=A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs). |journal=BMC Cell Biol. |volume=3 |issue=  |pages= 15 |year= 2002 |pmid= 12097147 |doi=  }}
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–1178 | year = 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–648 | year = 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
* {{cite journal | vauthors = Fujii M, Lyakh LA, Bracken CP, Fukuoka J, Hayakawa M, Tsukiyama T, Soll SJ, Harris M, Rocha S, Roche KC, Tominaga S, Jen J, Perkins ND, Lechleider RJ, Roberts AB | title = SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes | journal = Mol. Cell | volume = 24 | issue = 5 | pages = 771–783 | year = 2006 | pmid = 17157259 | doi = 10.1016/j.molcel.2006.11.006 }}
*{{cite journal | author=Colland F, Jacq X, Trouplin V, ''et al.'' |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324-32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104 }}
*{{cite journal  | author=Roche KC, Wiechens N, Owen-Hughes T, Perkins ND |title=The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression. |journal=Oncogene |volume=23 |issue= 50 |pages= 8185-95 |year= 2004 |pmid= 15378006 |doi= 10.1038/sj.onc.1208025 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal | author=Cui Q, Lim SK, Zhao B, Hoffmann FM |title=Selective inhibition of TGF-beta responsive genes by Smad-interacting peptide aptamers from FoxH1, Lef1 and CBP. |journal=Oncogene |volume=24 |issue= 24 |pages= 3864-74 |year= 2005 |pmid= 15750622 |doi= 10.1038/sj.onc.1208556 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Fujii M, Lyakh LA, Bracken CP, ''et al.'' |title=SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes. |journal=Mol. Cell |volume=24 |issue= 5 |pages= 771-83 |year= 2007 |pmid= 17157259 |doi= 10.1016/j.molcel.2006.11.006 }}
}}
{{refend}}
{{refend}}


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Latest revision as of 06:45, 11 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Smad nuclear-interacting protein 1 is a protein that in humans is encoded by the SNIP1 gene.[1][2][3]

Interactions

SNIP1 has been shown to interact with EP300.[1]

References

  1. 1.0 1.1 Kim RH, Wang D, Tsang M, Martin J, Huff C, de Caestecker MP, Parks WT, Meng X, Lechleider RJ, Wang T, Roberts AB (2000). "A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction". Genes Dev. 14 (13): 1605–16. doi:10.1101/gad.14.13.1605. PMC 316742. PMID 10887155.
  2. Roche KC, Wiechens N, Owen-Hughes T, Perkins ND (2004). "The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression". Oncogene. 23 (50): 8185–8195. doi:10.1038/sj.onc.1208025. PMID 15378006.
  3. "Entrez Gene: SNIP1 Smad nuclear interacting protein 1".

Further reading