SFPQ
| Splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | SFPQ ; PSF; POMP100 | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 3714 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE SFPQ 201586 s at tn.png | |||||||||||
| File:PBB GE SFPQ 201585 s at tn.png | |||||||||||
| File:PBB GE SFPQ 214016 s at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
Splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated), also known as SFPQ, is a human gene.[1]
References
Further reading
- Shav-Tal Y, Zipori D (2002). "PSF and p54(nrb)/NonO--multi-functional nuclear proteins". FEBS Lett. 531 (2): 109–14. PMID 12417296.
- Gower HJ, Moore SE, Dickson G; et al. (1990). "Cloning and characterization of a myoblast cell surface antigen defined by 24.1D5 monoclonal antibody". Development. 105 (4): 723–31. PMID 2480877.
- Gozani O, Patton JG, Reed R (1994). "A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction". EMBO J. 13 (14): 3356–67. PMID 8045264.
- Zhang WW, Zhang LX, Busch RK; et al. (1993). "Purification and characterization of a DNA-binding heterodimer of 52 and 100 kDa from HeLa cells". Biochem. J. 290 ( Pt 1): 267–72. PMID 8439294.
- Patton JG, Porro EB, Galceran J; et al. (1993). "Cloning and characterization of PSF, a novel pre-mRNA splicing factor". Genes Dev. 7 (3): 393–406. PMID 8449401.
- Clark J, Lu YJ, Sidhar SK; et al. (1997). "Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma". Oncogene. 15 (18): 2233–9. doi:10.1038/sj.onc.1201394. PMID 9393982.
- Teigelkamp S, Mundt C, Achsel T; et al. (1998). "The human U5 snRNP-specific 100-kD protein is an RS domain-containing, putative RNA helicase with significant homology to the yeast splicing factor Prp28p". RNA. 3 (11): 1313–26. PMID 9409622.
- Straub T, Grue P, Uhse A; et al. (1998). "The RNA-splicing factor PSF/p54 controls DNA-topoisomerase I activity by a direct interaction". J. Biol. Chem. 273 (41): 26261–4. PMID 9756848.
- Lutz CS, Cooke C, O'Connor JP; et al. (1998). "The snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor". RNA. 4 (12): 1493–9. PMID 9848648.
- Meissner M, Dechat T, Gerner C; et al. (2000). "Differential nuclear localization and nuclear matrix association of the splicing factors PSF and PTB". J. Cell. Biochem. 76 (4): 559–66. PMID 10653975.
- Urban RJ, Bodenburg Y, Kurosky A; et al. (2000). "Polypyrimidine tract-binding protein-associated splicing factor is a negative regulator of transcriptional activity of the porcine p450scc insulin-like growth factor response element". Mol. Endocrinol. 14 (6): 774–82. PMID 10847580.
- Straub T, Knudsen BR, Boege F (2000). "PSF/p54(nrb) stimulates "jumping" of DNA topoisomerase I between separate DNA helices". Biochemistry. 39 (25): 7552–8. PMID 10858305.
- Akhmedov AT, Lopez BS (2000). "Human 100-kDa homologous DNA-pairing protein is the splicing factor PSF and promotes DNA strand invasion". Nucleic Acids Res. 28 (16): 3022–30. PMID 10931916.
- de Vries H, Rüegsegger U, Hübner W; et al. (2000). "Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors". EMBO J. 19 (21): 5895–904. doi:10.1093/emboj/19.21.5895. PMID 11060040.
- Dye BT, Patton JG (2001). "An RNA recognition motif (RRM) is required for the localization of PTB-associated splicing factor (PSF) to subnuclear speckles". Exp. Cell Res. 263 (1): 131–44. doi:10.1006/excr.2000.5097. PMID 11161712.
- Mathur M, Tucker PW, Samuels HH (2001). "PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors". Mol. Cell. Biol. 21 (7): 2298–311. doi:10.1128/MCB.21.7.2298-2311.2001. PMID 11259580.
- Shav-Tal Y, Cohen M, Lapter S; et al. (2002). "Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactions". Mol. Biol. Cell. 12 (8): 2328–40. PMID 11514619.
- Zhang Z, Carmichael GG (2001). "The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs". Cell. 106 (4): 465–75. PMID 11525732.
- Andersen JS, Lyon CE, Fox AH; et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. PMID 11790298.
- Sewer MB, Nguyen VQ, Huang CJ; et al. (2002). "Transcriptional activation of human CYP17 in H295R adrenocortical cells depends on complex formation among p54(nrb)/NonO, protein-associated splicing factor, and SF-1, a complex that also participates in repression of transcription". Endocrinology. 143 (4): 1280–90. PMID 11897684.
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