SF1 (gene)

Splicing factor 1
File:PBB Protein SF1 image.jpg PDB rendering based on 1k1g.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1k1g​
Identifiers
Symbols	SF1 ; D11S636; ZFM1; ZNF162
External IDs	Template:OMIM5 Template:MGI HomoloGene: 6461
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SF1 208313 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Splicing factor 1, also known as SF1, is a human gene.

Further reading

• Krämer A (1992). "Purification of splicing factor SF1, a heat-stable protein that functions in the assembly of a presplicing complex". Mol. Cell. Biol. 12 (10): 4545–52. PMID 1406644.
• Toda T, Iida A, Miwa T; et al. (1994). "Isolation and characterization of a novel gene encoding nuclear protein at a locus (D11S636) tightly linked to multiple endocrine neoplasia type 1 (MEN1)". Hum. Mol. Genet. 3 (3): 465–70. PMID 7912130.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Naumovski L, Cleary ML (1996). "The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M". Mol. Cell. Biol. 16 (7): 3884–92. PMID 8668206.
• Arning S, Grüter P, Bilbe G, Krämer A (1996). "Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA". RNA. 2 (8): 794–810. PMID 8752089.CS1 maint: Multiple names: authors list (link)
• Abovich N, Rosbash M (1997). "Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals". Cell. 89 (3): 403–12. PMID 9150140.
• Caslini C, Spinelli O, Cazzaniga G; et al. (1997). "Identification of two novel isoforms of the ZNF162 gene: a growing family of signal transduction and activator of RNA proteins". Genomics. 42 (2): 268–77. doi:10.1006/geno.1997.4705. PMID 9192847.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang D, Childs G (1998). "Human ZFM1 protein is a transcriptional repressor that interacts with the transcription activation domain of stage-specific activator protein". J. Biol. Chem. 273 (12): 6868–77. PMID 9506990.
• Berglund JA, Abovich N, Rosbash M (1998). "A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition". Genes Dev. 12 (6): 858–67. PMID 9512519.CS1 maint: Multiple names: authors list (link)
• Krämer A, Quentin M, Mulhauser F (1998). "Diverse modes of alternative splicing of human splicing factor SF1 deduced from the exon-intron structure of the gene". Gene. 211 (1): 29–37. PMID 9573336.CS1 maint: Multiple names: authors list (link)
• Zhang D, Paley AJ, Childs G (1998). "The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription". J. Biol. Chem. 273 (29): 18086–91. PMID 9660765.CS1 maint: Multiple names: authors list (link)
• Neubauer G, King A, Rappsilber J; et al. (1998). "Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex". Nat. Genet. 20 (1): 46–50. doi:10.1038/1700. PMID 9731529.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang X, Bruderer S, Rafi Z; et al. (1999). "Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly". EMBO J. 18 (16): 4549–59. doi:10.1093/emboj/18.16.4549. PMID 10449420.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lapteva N, Nieda M, Ando Y; et al. (2001). "Expression of renin-angiotensin system genes in immature and mature dendritic cells identified using human cDNA microarray". Biochem. Biophys. Res. Commun. 285 (4): 1059–65. doi:10.1006/bbrc.2001.5215. PMID 11467860.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Goldstrohm AC, Albrecht TR, Suñé C; et al. (2001). "The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1". Mol. Cell. Biol. 21 (22): 7617–28. doi:10.1128/MCB.21.22.7617-7628.2001. PMID 11604498.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liu Z, Luyten I, Bottomley MJ; et al. (2001). "Structural basis for recognition of the intron branch site RNA by splicing factor 1". Science. 294 (5544): 1098–102. doi:10.1126/science.1064719. PMID 11691992.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rappsilber J, Ryder U, Lamond AI, Mann M (2002). "Large-scale proteomic analysis of the human spliceosome". Genome Res. 12 (8): 1231–45. doi:10.1101/gr.473902. PMID 12176931.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Selenko P, Gregorovic G, Sprangers R; et al. (2003). "Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP". Mol. Cell. 11 (4): 965–76. PMID 12718882.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lin KT, Lu RM, Tarn WY (2004). "The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo". Mol. Cell. Biol. 24 (20): 9176–85. doi:10.1128/MCB.24.20.9176-9185.2004. PMID 15456888.CS1 maint: Multiple names: authors list (link)