SCRIB

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Scribbled homolog (Drosophila)
File:PBB Protein SCRIB image.jpg
PDB rendering based on 1uju.
Available structures
PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB
Identifiers
Symbols SCRIB ; CRIB1; SCRB1; SCRIB1; Vartul
External IDs Template:OMIM5 Template:MGI HomoloGene44228
RNA expression pattern
File:PBB GE SCRIB 212556 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Scribbled homolog (Drosophila), also known as SCRIB, is a human gene.[1]


References

  1. "Entrez Gene: SCRIB scribbled homolog (Drosophila)".

Further reading

  • Nakajima D, Okazaki N, Yamakawa H; et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. PMID 12168954.
  • Nagase T, Seki N, Tanaka A; et al. (1996). "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (4): 167–74, 199–210. PMID 8590280.
  • Nakagawa S, Huibregtse JM (2000). "Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase". Mol. Cell. Biol. 20 (21): 8244–53. PMID 11027293.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Dow LE, Brumby AM, Muratore R; et al. (2004). "hScrib is a functional homologue of the Drosophila tumour suppressor Scribble". Oncogene. 22 (58): 9225–30. doi:10.1038/sj.onc.1207154. PMID 14681682.
  • Nakagawa S, Yano T, Nakagawa K; et al. (2004). "Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix". Br. J. Cancer. 90 (1): 194–9. doi:10.1038/sj.bjc.6601465. PMID 14710229.
  • Bouwmeester T, Bauch A, Ruffner H; et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216.
  • Brill LM, Salomon AR, Ficarro SB; et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
  • Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMID 15231747.
  • Borg JP (2004). "[hScrib: a potential novel tumor suppressor]". Pathol. Biol. 52 (6): 328–31. doi:10.1016/j.patbio.2003.09.015. PMID 15261375.
  • Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
  • Ballif BA, Villén J, Beausoleil SA; et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Petit MM, Meulemans SM, Alen P; et al. (2006). "The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus". BMC Cell Biol. 6 (1): 1. doi:10.1186/1471-2121-6-1. PMID 15649318.
  • Barrios-Rodiles M, Brown KR, Ozdamar B; et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
  • Lahuna O, Quellari M, Achard C; et al. (2005). "Thyrotropin receptor trafficking relies on the hScrib-betaPIX-GIT1-ARF6 pathway". EMBO J. 24 (7): 1364–74. doi:10.1038/sj.emboj.7600616. PMID 15775968.
  • Navarro C, Nola S, Audebert S; et al. (2005). "Junctional recruitment of mammalian Scribble relies on E-cadherin engagement". Oncogene. 24 (27): 4330–9. doi:10.1038/sj.onc.1208632. PMID 15806148.
  • Métais JY, Navarro C, Santoni MJ; et al. (2005). "hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cells". FEBS Lett. 579 (17): 3725–30. doi:10.1016/j.febslet.2005.05.062. PMID 15975580.
  • Thomas M, Massimi P, Navarro C; et al. (2005). "The hScrib/Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteins". Oncogene. 24 (41): 6222–30. doi:10.1038/sj.onc.1208757. PMID 16103886.

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