SCAND1

SCAN domain containing 1
Identifiers
Symbols	SCAND1 ; RAZ1; SDP1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 10642
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SCAND1 218206 x at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

SCAN domain containing 1, also known as SCAND1, is a human gene.

The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. Functional studies have established that the SCAN box is a protein interaction domain that mediates both hetero- and homoprotein associations, and maybe involved in regulation of transcriptional activity. Two transcript variants with different 5' UTRs, but encoding the same protein, have been described for this gene.

Further reading

• Williams AJ, Blacklow SC, Collins T (2000). "The zinc finger-associated SCAN box is a conserved oligomerization domain". Mol. Cell. Biol. 19 (12): 8526–35. PMID 10567577.CS1 maint: Multiple names: authors list (link)
• Schumacher C, Wang H, Honer C; et al. (2000). "The SCAN domain mediates selective oligomerization". J. Biol. Chem. 275 (22): 17173–9. doi:10.1074/jbc.M000119200. PMID 10747874.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sander TL, Haas AL, Peterson MJ, Morris JF (2000). "Identification of a novel SCAN box-related protein that interacts with MZF1B. The leucine-rich SCAN box mediates hetero- and homoprotein associations". J. Biol. Chem. 275 (17): 12857–67. PMID 10777584.CS1 maint: Multiple names: authors list (link)
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. PMID 11076863.CS1 maint: Multiple names: authors list (link)
• Deloukas P, Matthews LH, Ashurst J; et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sander TL, Morris JF (2003). "Characterization of the SCAN box encoding RAZ1 gene: analysis of cDNA transcripts, expression, and cellular localization". Gene. 296 (1–2): 53–64. PMID 12383503.
• Babb R, Bowen BR (2003). "SDP1 is a peroxisome-proliferator-activated receptor gamma 2 co-activator that binds through its SCAN domain". Biochem. J. 370 (Pt 2): 719–27. doi:10.1042/BJ20021378. PMID 12444922.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wiemann S, Arlt D, Huber W; et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mehrle A, Rosenfelder H, Schupp I; et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Carneiro FR, Silva TC, Alves AC; et al. (2006). "Spectroscopic characterization of the tumor antigen NY-REN-21 and identification of heterodimer formation with SCAND1". Biochem. Biophys. Res. Commun. 343 (1): 260–8. doi:10.1016/j.bbrc.2006.02.140. PMID 16540086.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)