SAV1: Difference between revisions

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{{Underlinked|date=June 2016}}
 
{{Infobox_gene}}
{{Infobox_gene}}
'''Protein salvador homolog 1''' is a [[protein]] that in humans is encoded by the ''SAV1'' [[gene]].<ref name="pmid12202036">{{cite journal | vauthors = Tapon N, Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber DA, Hariharan IK | title = salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines | journal = Cell | volume = 110 | issue = 4 | pages = 467–78 |date=Aug 2002 | pmid = 12202036 | pmc =  | doi =10.1016/S0092-8674(02)00824-3  }}</ref><ref name="pmid11027580">{{cite journal | author = Valverde P | title = Cloning, expression, and mapping of hWW45, a novel human WW domain-containing gene | journal = Biochem Biophys Res Commun | volume = 276 | issue = 3 | pages = 990–8 |date=Oct 2000 | pmid = 11027580 | pmc =  | doi = 10.1006/bbrc.2000.3582 }}</ref><ref name="entrez"/>
'''Protein salvador homolog 1''' is a [[protein]] that in humans is encoded by the ''SAV1'' [[gene]].<ref name="pmid12202036">{{cite journal | vauthors = Tapon N, Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber DA, Hariharan IK | title = salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines | journal = Cell | volume = 110 | issue = 4 | pages = 467–78 |date=Aug 2002 | pmid = 12202036 | pmc =  | doi =10.1016/S0092-8674(02)00824-3  }}</ref><ref name="pmid11027580">{{cite journal | author = Valverde P | title = Cloning, expression, and mapping of hWW45, a novel human WW domain-containing gene | journal = Biochem Biophys Res Commun | volume = 276 | issue = 3 | pages = 990–8 |date=Oct 2000 | pmid = 11027580 | pmc =  | doi = 10.1006/bbrc.2000.3582 }}</ref><ref name="entrez"/>
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{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = WW domain-containing proteins are found in all [[eukaryotes]] and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a coiled-coil region. It is ubiquitously expressed in adult tissues. The encoded protein is 94% identical to the mouse protein at the amino acid level.<ref name="entrez">{{cite web | title = Entrez Gene: SAV1 salvador homolog 1 (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=60485| accessdate = }}</ref>
| summary_text = WW domain-containing proteins are found in all [[eukaryotes]] and play an important role in the regulation of a wide variety of cellular functions such as [[protein degradation]], [[transcription (biology)|transcription]], and [[RNA splicing]]. This gene encodes a protein which contains 2 WW domains and a coiled-coil region. It is ubiquitously [[gene expression|expressed]] in adult tissues. The encoded protein is 94% identical to the mouse protein at the amino acid level.<ref name="entrez">{{cite web | title = Entrez Gene: SAV1 salvador homolog 1 (Drosophila)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=60485| accessdate = }}</ref>
}}
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Latest revision as of 06:32, 10 January 2019

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Protein salvador homolog 1 is a protein that in humans is encoded by the SAV1 gene.[1][2][3]

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a coiled-coil region. It is ubiquitously expressed in adult tissues. The encoded protein is 94% identical to the mouse protein at the amino acid level.[3]

References

  1. Tapon N, Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber DA, Hariharan IK (Aug 2002). "salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines". Cell. 110 (4): 467–78. doi:10.1016/S0092-8674(02)00824-3. PMID 12202036.
  2. Valverde P (Oct 2000). "Cloning, expression, and mapping of hWW45, a novel human WW domain-containing gene". Biochem Biophys Res Commun. 276 (3): 990–8. doi:10.1006/bbrc.2000.3582. PMID 11027580.
  3. 3.0 3.1 "Entrez Gene: SAV1 salvador homolog 1 (Drosophila)".

Further reading