Right ventricular outflow tract obstruction pathophysiology

Right ventricular outflow tract obstruction Microchapters
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Anatomy of Pulmonary Valve
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Pulmonary valve stenosis
Pulmonary subvalvular stenosis
Pulmonary supravalvular stenosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Pathophysiology

Pulmonary valve stenosis is one of the most common RVOT obstructions. The oxygen-depleted blood is coming from the body to the heart through the superior and inferior vena cava, arriving into the right atrium, right ventricle, passing through the RVOT and pulmonary valve to the pulmonary artery and lungs to pick up oxygen. Normally the pulmonary valve has three leaflets. These leaflets can be malformed due to congenital defects, producing pulmonary valve narrowing (stenotic) or leaky (insufficient). If the pulmonary valve is tight (stenosis), the right side of the heart needs to work harder to push blood through the valve to the lungs. The stenosis, insufficiency or both can be mild to severe. Therefore the symptoms will depend upon the grades of pulmonary stenosis.