Rift valley fever laboratory findings: Difference between revisions
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{{Rift valley fever}} | {{Rift valley fever}} | ||
==Diagnostic studies== | |||
*The main purpose is to detect the virus in the blood, which can be accomplished by a few tests. | |||
*[[Reverse transcription polymerase chain reaction|RT-PCR]] (reverse transcriptase-polymerase chain reaction) and [[Enzyme linked immunosorbent assay (ELISA)|ELISA test]] (for [[Antigen|antigen]] detection) may be used during the initial phase of the illness. | |||
*[[Immunoglobulin M|IgM]] Antibodies : Once the viral load decreases in the blood, IgM antibody tests are helpful in detecting the presence of ongoing [[Infection|infection]]. | |||
*[[Immunoglobulin G|IgG]] Antibodies : In recovered cases, testing for IgG antibodies aid in identifying cases who may have had a recent episode of RVF. | |||
==Common Lab Findings== | |||
*In majority of cases, lab findings will not be significant for anything else except [[Fever|fever]] and [[Hypotension|low blood pressure]]. | *In majority of cases, lab findings will not be significant for anything else except [[Fever|fever]] and [[Hypotension|low blood pressure]]. | ||
*[[Anemia|Low hemoglobin]] levels, [[Jaundice|raised bilirubin levels]] along with deranged blood coagulation profile and [[Thrombycytopenia|decreased platelet counts]] are seen in hemorrhagic RVF. | *[[Anemia|Low hemoglobin]] levels, [[Jaundice|raised bilirubin levels]] along with deranged blood coagulation profile and [[Thrombycytopenia|decreased platelet counts]] are seen in hemorrhagic RVF. |
Revision as of 16:12, 16 July 2021
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Diagnostic studies
- The main purpose is to detect the virus in the blood, which can be accomplished by a few tests.
- RT-PCR (reverse transcriptase-polymerase chain reaction) and ELISA test (for antigen detection) may be used during the initial phase of the illness.
- IgM Antibodies : Once the viral load decreases in the blood, IgM antibody tests are helpful in detecting the presence of ongoing infection.
- IgG Antibodies : In recovered cases, testing for IgG antibodies aid in identifying cases who may have had a recent episode of RVF.
Common Lab Findings
- In majority of cases, lab findings will not be significant for anything else except fever and low blood pressure.
- Low hemoglobin levels, raised bilirubin levels along with deranged blood coagulation profile and decreased platelet counts are seen in hemorrhagic RVF.
- Increased leukocytes in CSF along with presence of viral load in CSF would indicate encephalitis or meningitis due to RVF.