Rifapentine

Rifapentine

File:Rifapentine.png
Clinical data
ATC code	J04AB05 (WHO)
Pharmacokinetic data
Bioavailability	increases when administered with food
Identifiers
IUPAC name 3{[(4-cyclopentyl-1-piperazinyl)imino]methyl}rifamycin
CAS Number	61379-65-5
PubChem CID	5462354
DrugBank	APRD01217
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C47H64N4O12
Molar mass	877.031 g/mol

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Rifapentine (marketed under the brand name Priftin by Aventis) is an antibiotic drug used in the treatment of tuberculosis.

History

Rifapentin was first synthesized in 1965 by the same company that produced rifampin. The drug was approved by the Food and Drug Administration (FDA) in June 1998.

External links

• Rosenthal IM, Zhang M, Williams KN, Peloquin CA, Tyagi S, et al. 2007. Daily Dosing of Rifapentine Cures Tuberculosis in Three Months or Less in the Murine Model. PLoS Medicine Vol. 4, No. 12, e344 doi:10.1371/journal.pmed.0040344 [2]