Rhinitis laboratory findings: Difference between revisions

Jump to navigation Jump to search
Line 4: Line 4:
==Overview==
==Overview==
==Laboratory Findings==
==Laboratory Findings==
The presenting symptoms of allergic and nonallergic rhinitis are sometimes difficult to distinguish, and it is often a diagnostic challenge to determine the etiology of rhinitis, whether it is allergic or nonallergic (or even an overlap of the two conditions).<ref name="pmid17153005">{{cite journal| author=Settipane RA, Charnock DR| title=Epidemiology of rhinitis: allergic and nonallergic. | journal=Clin Allergy Immunol | year= 2007 | volume= 19 | issue=  | pages= 23-34 | pmid=17153005 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17153005  }} </ref> The accurate diagnosis allergic rhinitis relies on the clinical history, and the demonstration of the presence of allergic sensitization towards relevant allergens.<ref name="Allergic rhinitis-an overview of a common disease">{{cite journal |last=Rotiroti |first=Giuseppina |last2=Scadding |first2=Glenis |date=July 2016 |title=Allergic Rhinitis-an overview of a common disease |url=https://www-clinicalkey-com.ezp-prod1.hul.harvard.edu/#!/content/playContent/1-s2.0-S1751722216300063?returnurl=null&referrer=null&scrollTo=%23tbl2|journal=Paediatrics and Child Health |volume= Volume 26 |issue= Issue 7 |pages=298-303 |access-date=January 20, 2017 }} </ref><ref name="pmid18331513">{{cite journal| author=Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A et al.| title=Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). | journal=Allergy | year= 2008 | volume= 63 Suppl 86 | issue=  | pages= 8-160 | pmid=18331513 | doi=10.1111/j.1398-9995.2007.01620.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18331513  }} </ref>  Nonallergic rhinitis is a heterogeneous condition with a wide range of nasal pathological findings, which may require more targeted investigations. Allergy investigations are never used alone for diagnosis because of the low specificity, and the test result should be interpreted in conjunction with the clinical history.<ref name="Allergic rhinitis-an overview of a common disease" />
The presenting symptoms of allergic and nonallergic rhinitis are sometimes difficult to distinguish, and it is often a diagnostic challenge to determine the etiology of rhinitis, whether it is allergic or nonallergic (or even an overlap of the two conditions).<ref name="pmid17153005">{{cite journal| author=Settipane RA, Charnock DR| title=Epidemiology of rhinitis: allergic and nonallergic. | journal=Clin Allergy Immunol | year= 2007 | volume= 19 | issue=  | pages= 23-34 | pmid=17153005 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17153005  }} </ref> The accurate diagnosis allergic rhinitis relies on the clinical history, and the demonstration of the presence of allergic sensitization towards relevant allergens.<ref name="Allergic rhinitis-an overview of a common disease">{{cite journal |last=Rotiroti |first=Giuseppina |last2=Scadding |first2=Glenis |date=July 2016 |title=Allergic Rhinitis-an overview of a common disease |url=https://www-clinicalkey-com.ezp-prod1.hul.harvard.edu/#!/content/playContent/1-s2.0-S1751722216300063?returnurl=null&referrer=null&scrollTo=%23tbl2|journal=Paediatrics and Child Health |volume= Volume 26 |issue= Issue 7 |pages=298-303 |access-date=January 20, 2017 }} </ref><ref name="pmid18331513">{{cite journal| author=Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A et al.| title=Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). | journal=Allergy | year= 2008 | volume= 63 Suppl 86 | issue=  | pages= 8-160 | pmid=18331513 | doi=10.1111/j.1398-9995.2007.01620.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18331513  }} </ref>  Nonallergic rhinitis is a heterogeneous condition with a wide range of nasal pathological findings, which may require more targeted investigations.<ref name="pmid21783242">{{cite journal| author=Greiner AN, Hellings PW, Rotiroti G, Scadding GK| title=Allergic rhinitis. | journal=Lancet | year= 2011 | volume= 378 | issue= 9809 | pages= 2112-22 | pmid=21783242 | doi=10.1016/S0140-6736(11)60130-X | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21783242  }} </ref> Allergy investigations are never used alone for diagnosis because of the low specificity, and the test result should be interpreted in conjunction with the clinical history.<ref name="Allergic rhinitis-an overview of a common disease" />


Determination of allergic sensitization is usually done via the following methods:
Determination of allergic sensitization is usually done via the following methods:
Line 10: Line 10:
# RAST (radioallergosorbent test)- This is a blood test that detect specific IgE antibodies using radioimmunoassay test  
# RAST (radioallergosorbent test)- This is a blood test that detect specific IgE antibodies using radioimmunoassay test  
# ''Nasal allergen challenge''- This is not routinely done
# ''Nasal allergen challenge''- This is not routinely done
==References==
==References==
{{reflist|2}}
{{reflist|2}}
{{WH}}
{{WH}}
{{WS}}
{{WS}}

Revision as of 17:42, 23 January 2017

Rhinitis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Rhinitis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Rhinitis laboratory findings On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Rhinitis laboratory findings

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Rhinitis laboratory findings

CDC on Rhinitis laboratory findings

Rhinitis laboratory findings in the news

Blogs on Rhinitis laboratory findings

Directions to Hospitals Treating Rhinitis

Risk calculators and risk factors for Rhinitis laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Fatimo Biobaku M.B.B.S [2]

Overview

Laboratory Findings

The presenting symptoms of allergic and nonallergic rhinitis are sometimes difficult to distinguish, and it is often a diagnostic challenge to determine the etiology of rhinitis, whether it is allergic or nonallergic (or even an overlap of the two conditions).[1] The accurate diagnosis allergic rhinitis relies on the clinical history, and the demonstration of the presence of allergic sensitization towards relevant allergens.[2][3] Nonallergic rhinitis is a heterogeneous condition with a wide range of nasal pathological findings, which may require more targeted investigations.[4] Allergy investigations are never used alone for diagnosis because of the low specificity, and the test result should be interpreted in conjunction with the clinical history.[2]

Determination of allergic sensitization is usually done via the following methods:

  1. Skin prick test, OR
  2. RAST (radioallergosorbent test)- This is a blood test that detect specific IgE antibodies using radioimmunoassay test
  3. Nasal allergen challenge- This is not routinely done

References

  1. Settipane RA, Charnock DR (2007). "Epidemiology of rhinitis: allergic and nonallergic". Clin Allergy Immunol. 19: 23–34. PMID 17153005.
  2. 2.0 2.1 Rotiroti, Giuseppina; Scadding, Glenis (July 2016). "Allergic Rhinitis-an overview of a common disease". Paediatrics and Child Health. Volume 26 (Issue 7): 298–303. Retrieved January 20, 2017.
  3. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A; et al. (2008). "Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen)". Allergy. 63 Suppl 86: 8–160. doi:10.1111/j.1398-9995.2007.01620.x. PMID 18331513.
  4. Greiner AN, Hellings PW, Rotiroti G, Scadding GK (2011). "Allergic rhinitis". Lancet. 378 (9809): 2112–22. doi:10.1016/S0140-6736(11)60130-X. PMID 21783242.

Template:WH Template:WS