Rheumatic fever primary prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Lance Christiansen, D.O.; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Prevention

Primary Prevention of Rheumatic Fever (Treatment of Streptococcal pharyngitis)[1]
Agent Children ≤ 27 kg (60 lb) Adolescents and Adults > 27 kg (60 lb) Mode Duration Rating
Penicillin Therapy
Penicillin V (phenoxymethyl penicillin) 250 mg 2 to 3 times daily 500 mg 2 to 3 times daily Oral 10 days Class I, LOE B
or
Amoxicillin 50 mg/kg once daily (maximum 1 g) 50 mg/kg once daily (maximum 1 g) Oral 10 days Class I, LOE B
or
Benzathine penicillin G 600,000 U 1,200,000 U Intramuscular Once Class I, LOE B

References

  1. Gerber MA, Baltimore RS, Eaton CB, Gewitz M, Rowley AH, Shulman ST; et al. (2009). "Prevention of rheumatic fever and diagnosis and treatment of acute Streptococcal pharyngitis: a scientific statement from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, the Interdisciplinary Council on Functional Genomics and Translational Biology, and the Interdisciplinary Council on Quality of Care and Outcomes Research: endorsed by the American Academy of Pediatrics". Circulation. 119 (11): 1541–51. doi:10.1161/CIRCULATIONAHA.109.191959. PMID 19246689.

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