Rheumatic fever laboratory findings: Difference between revisions
m (Changes made per Mahshid's request) |
Farima Kahe (talk | contribs) |
||
| Line 33: | Line 33: | ||
===Biopsy of Endocardium=== | ===Biopsy of Endocardium=== | ||
Though [[endomyocardial biopsy]] may help in confirming the presence of [[carditis]], it is not recommended as a routine diagnostic and prognostic tool.<ref name="pmid8222115">{{cite journal| author=Narula J, Chopra P, Talwar KK, Reddy KS, Vasan RS, Tandon R et al.| title=Does endomyocardial biopsy aid in the diagnosis of active rheumatic carditis? | journal=Circulation | year= 1993 | volume= 88 | issue= 5 Pt 1 | pages= 2198-205 | pmid=8222115 | doi= | pmc= | url= }} </ref> | Though [[endomyocardial biopsy]] may help in confirming the presence of [[carditis]], it is not recommended as a routine diagnostic and prognostic tool.<ref name="pmid8222115">{{cite journal| author=Narula J, Chopra P, Talwar KK, Reddy KS, Vasan RS, Tandon R et al.| title=Does endomyocardial biopsy aid in the diagnosis of active rheumatic carditis? | journal=Circulation | year= 1993 | volume= 88 | issue= 5 Pt 1 | pages= 2198-205 | pmid=8222115 | doi= | pmc= | url= }} </ref> | ||
There are no diagnostic laboratory findings associated with [disease name]. | |||
OR | |||
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name]. | |||
OR | |||
[Test] is usually normal among patients with [disease name]. | |||
OR | |||
Laboratory findings consistent with the diagnosis of [disease name] include: | |||
*[Abnormal test 1] | |||
*[Abnormal test 2] | |||
*[Abnormal test 3] | |||
OR | |||
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication]. | |||
==References== | ==References== | ||
Revision as of 19:14, 17 February 2020
|
Rheumatic fever Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Rheumatic fever laboratory findings On the Web |
|
American Roentgen Ray Society Images of Rheumatic fever laboratory findings |
|
Risk calculators and risk factors for Rheumatic fever laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Varun Kumar, M.B.B.S. Anthony Gallo, B.S. [2]
Overview
Laboratory findings consistent with the diagnosis of rheumatic fever include elevated inflammatory markers, presence of streptococcal infection, and elevated or rising antistreptolysin O antibody titer.
Laboratory Findings
Inflammatory Markers
The following inflammatory markers are often elevated:
Throat Culture
Throat culture for group A beta-hemolytic streptococci may be performed. However many patients may have negative culture when rheumatic fever develops.[1]
Rapid Streptococcal Antigen
Rapid streptococcal antigen test may be performed. However, it has a lower sensitivity (70%) and statistically equal specificity (98%) as throat culture; a negative test results rules out streptococcal infection.[2]
Antistreptolysin O Antibody
Elevated or rising antistreptolysin O antibody titer is often noted. The antibodies usually peak approximately during fourth or fifth week after the onset of infection. Patients should be tested at intervals of two weeks to detect raising titers. Antistreptococcal antibodies may also be noted in patients who are streptococcal carriers with asymptomatic pharyngitis.
Leukocytosis
A marked leukocytosis is present.
C-Reactive Protein
An elevated C-reactive protein level is present.
Erythrocyte Sedimentation Rate
An elevated erythrocyte sedimentation rate is present.
Biopsy of Endocardium
Though endomyocardial biopsy may help in confirming the presence of carditis, it is not recommended as a routine diagnostic and prognostic tool.[3]
There are no diagnostic laboratory findings associated with [disease name].
OR
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
OR
[Test] is usually normal among patients with [disease name].
OR
Laboratory findings consistent with the diagnosis of [disease name] include:
- [Abnormal test 1]
- [Abnormal test 2]
- [Abnormal test 3]
OR
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
References
- ↑ "Guidelines for the diagnosis of rheumatic fever. Jones Criteria, 1992 update. Special Writing Group of the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young of the American Heart Association". JAMA. 268 (15): 2069–73. 1992. PMID 1404745.
- ↑ Choby BA (2009). "Diagnosis and treatment of streptococcal pharyngitis". Am Fam Physician. 79 (5): 383–90. PMID 19275067.
- ↑ Narula J, Chopra P, Talwar KK, Reddy KS, Vasan RS, Tandon R; et al. (1993). "Does endomyocardial biopsy aid in the diagnosis of active rheumatic carditis?". Circulation. 88 (5 Pt 1): 2198–205. PMID 8222115.