Rhabdomyosarcoma medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]

Overview

Treatment for rhabdomyosarcoma may consists of chemotherapy, radiation therapy and surgery. Chemotherapy may be given as neoadjuvant chemotherapy or adjuvant chemotherapy. Radiation therapy may be used as local therapy.

Medical Therapy

  • Rhabdomyosarcoma treatment include combination of surgery, radiotherapy, and chemotherapy.
  • Rhabdomyosarcoma treatments depends on staging classification and risk stratification. For more information click here.

Chemotherapy

Chemotherapy may be given as neoadjuvant chemotherapy or adjuvant chemotherapy. The most common drugs used to treat rhabdomyosarcoma are:[1]

Radiotherapy

The treatment for rhabdomyosarcoma varies depending upon the location of tumor:[2]

Treatment for rhabdomyosarcoma
Location Symptoms
Head and neck Wide local excision; chemotherapy +/- radiation therapy
Bone around the eye Biopsy; chemotherapy + radiation therapy
Extremities Wide local excision; resection of nearby lymph nodes; amputation for extensive tumors
Abdomen or pelvis Neoadjvant therapy with chemotherapy and radiotherapy; wide local excision
Paratesticular region Removal of testes and spermatic cord; ipsilateral retroperitoneal lymphnode resection

References

  1. "Rhabdomyosarcoma".
  2. "Surgery for Rhabdomyosarcoma".

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