Rhabdomyosarcoma laboratory findings: Difference between revisions

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==Overview==
==Overview==
==Laboratory Findings==
When rhabdomyosarcoma is suspected, tests will be run for blood, muscle, and marrow.
Diagnosis of rhabdomyosarcoma depends on recognition of [[differentiation]] toward skeletal muscle cells.  The protein ''myo D1'' is a protein normally found in developing skeletal muscle cells which disappears after the muscle matures and becomes innervated by a [[nerve]].  Thus, myo D1 is not found in normal skeletal muscle and serves as a useful immunohistochemical marker of rhabdomyosarcoma.
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 18:41, 12 September 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Laboratory Findings

When rhabdomyosarcoma is suspected, tests will be run for blood, muscle, and marrow.

Diagnosis of rhabdomyosarcoma depends on recognition of differentiation toward skeletal muscle cells. The protein myo D1 is a protein normally found in developing skeletal muscle cells which disappears after the muscle matures and becomes innervated by a nerve. Thus, myo D1 is not found in normal skeletal muscle and serves as a useful immunohistochemical marker of rhabdomyosarcoma.

References

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