Respiratory failure: Difference between revisions

Jump to navigation Jump to search
No edit summary
m (Bot: Automated text replacement (-Category:Primary care +))
 
(25 intermediate revisions by 11 users not shown)
Line 1: Line 1:
{{Infobox_Disease |
  Name          = {{PAGENAME}} |
  Image          = |
  Caption        = |
  DiseasesDB    = 6623 |
  ICD10          = {{ICD10|J|96||j|95}} |
  ICD9          = {{ICD9|518.81}} |
  ICDO          = |
  OMIM          = |
  MedlinePlus    = |
  eMedicineSubj  = med |
  eMedicineTopic = 2011|
  MeshID        = D012131 |
}}
{{SI}}
{{CMG}}
__NOTOC__
__NOTOC__
'''Associate Editor-In-Chief:''' {{CZ}}  {{MUT}}
{| class="infobox" style="float:right;"
 
{{Editor Help}}
 
==Overview==
 
'''Respiratory failure''' is a [[medicine|medical]] term for inadequate [[gas exchange]] by the [[respiratory system]]. Respiratory failure can be indicated by observing a drop in blood [[oxygen]] level ([[Hypoxia (medical)|hypoxemia]]) and/or a rise in arterial [[carbon dioxide]] ([[hypercapnia]]) which can be written as ([[Partial pressure|Pa]][[Oxygen|O2]] < 60 mmHg, [[Partial pressure|Pa]]CO2 >45 mmHg).
 
Classification into type I or type II relates to the absence or presence of hypercapnia respectively. (Values in kPA being PO2 below 8kPA and PCO2 above 6.7kPa
 
==Types==
===Type 1===
*Type 1 respiratory failure is defined as [[hypoxia]] without [[hypercapnia]], indeed the CO<sub>2</sub> level may be normal or low. It is typically caused by a ventilation/perfusion mismatch; the air flowing in and out of the lungs is not matched with the flow of blood to the lungs. This type is caused by conditions that affect oxygenation like:
 
1.parenchymal disease (v-q mismatch)
 
2.diseases of vasculature and shunts.
 
===Type 2===
 
*Type 2 respiratory failure is defined  build up of carbon dioxide that has been generated by the body. The underlying causes are reduced breathing effort (in the fatigued patient), increased resistance to breathing (such as in [[asthma]]) or an increase in the area of the lung that is not available for gas exchange (such as in [[emphysema]]).
 
==Causes==
 
Respiratory Depression
 
*[[Codeine]],
*[[Clozapine]],
*[[Fentanyl]],
*[[Gamma-Hydroxybutyric acid]],
*[[Heroin]],
*[[Ketamine]],
*[[Lidocaine]],
*[[Labetalol]],
*[[Lorazepam]],
*[[Morphine]],
*[[Nitrazepam]],
*[[Opiate]],
*[[Oxymorphone]],
*[[Procainamide (patient information)]],
*[[Sodium thiopental]],
*[[Triazolam]],
*[[Zopiclone]],
 
Respiratory Distress
 
*[[Glycogen storage disease type I]],
*[[Hemosiderosis]],
*[[Human ehrlichiosis]],
*[[Infant respiratory distress syndrome]],
*[[Multiple chemical sensitivity]],
*[[Potter syndrome]],
*[[Pre-eclampsia]],
 
Other
 
*[[Fatigue]] due to prolonged [[hyperventilation|tachypnoea]] in [[metabolic acidosis]]
 
 
 
==Complete Differential Diagnosis of Causes of Respiratory Failure==
 
 
(In alphabetical order)
{{MultiCol}}
*[[3-Quinuclidinyl benzilate]]
*[[Abrin]]
*[[Acetylsalicylic acid]]
*[[Achondrogenesis]]
*Acute lung syndrome
*[[Acute motor axonal neuropathy]]
*[[Acute Porphyria]]
*[[Acute Respiratory Distress Syndrome]]
*[[Alcohol]]
*[[Aldicarb]]
*[[Alpha 1-antitrypsin deficiency]]
*[[Alpha-amanitin]]
*[[Amyotrophic Lateral Sclerosis]]
*[[Anaphylaxis]]
*[[Angioedema]]
*[[Antiphospholipid Antibody Syndrome]]
*[[Asbestosis]]
*[[Aspiration]]
*[[Atelectasis]]
*[[Atelosteogenesis, type II]]
*[[Atrial septal defect (ostium primum)]]
*[[Babesiosis]]
*[[Barium nitrate]]
*[[Becker's muscular dystrophy]]
*[[Bland-White-Garland Syndrome]]
*[[Blood transfusion]]
*[[Botulism]]
*[[Bronchial asthma]]
*[[Bronchiectasis]]
*[[Bronchiolitis]]
*[[Bronchiolitis obliterans]]
*[[Bronchogenic carcinoma]]
*[[Bronchopulmonary dysplasia]]
*[[Bufotenin]]
*[[Bungarotoxin]]
*[[Carbon monoxide poisoning]]
*[[Carnitine palmitoyltransferase II deficiency]]
*[[Cholesterol Emboli Syndrome]]
*[[Chronic Obstructive Pulmonary Disease]]
*[[Clitocybe dealbata]]
*[[Clozapine]]
*Coal worker pneumoconiosis
*[[Cocaine]]
*[[Codeine]]
*[[Colchicine]]
*[[Cone snail]]
*[[Congenital Central Hypoventilation Syndrome]]
*[[Congenital diaphragmatic hernia]]
*[[Crimean-Congo hemorrhagic fever]]
*[[Cystic adenomatoid malformation of lung]]
*[[Cystic fibrosis]]
*[[Cytisine]]
*[[Devic's disease]]
*[[Dicofol]]
*[[Duchenne's Muscular Dystrophy]]
*[[Ebstein anomaly]]
*[[Eisenmenger syndrome]]
*Elecrolyte abnormalities
*[[Emphysema]]
*[[Eosinophilic pneumonia]]
*[[EVAR]]
*[[Fallot tetralogy]]
*[[Familial dysautonomia]]
*[[Fat embolism]]
*[[Fentanyl]]
*[[Fetal circulation, persistent]]
*[[Fibrosing alveolitis]]
*[[Flail chest]]
*[[Foreign body]]
*[[Furfural]]
*[[Gamma-Hydroxybutyric acid]]
*[[Glotto Emphysema]]
*[[Glycogen storage disease type I]]
*[[Guillain-Barre syndrome]]
{{ColBreak}}
*[[Hamman-Rich Syndrome]]
*[[Hantavirus Pulmonary Syndrome]]
*[[Heartworm]]
*[[Hemosiderosis]]
*[[Hepatic failure]]
*[[Hepatopulmonary syndrome]]
*[[Hereditary haemorrhagic telangiectasia]]
*[[Heroin]]
*[[Human ehrlichiosis]]
*[[Infant respiratory distress syndrome]]
*[[Interstitial fibrosis]]
*[[Ketamine]]
*[[Kyphoscoliosis]]
*[[Labetalol]]
*[[Laryngo-/Bronchospasm]]
*[[Legionella pneumophila]]
*[[Lidocaine]]
*[[Lorazepam]]
*[[Malignant hyperpyrexia]]
*[[Malignant Mesothelioma]]
*[[Marine toxins]]
*[[Meningitis]]
*[[Metabolic Acidosis]]
*[[Morphine]]
*[[Multiple chemical sensitivity]]
*[[Multiple organ dysfunction syndrome]]
*[[Muscarine]]
*[[Myasthenia Gravis]]
*Near-drowning
*[[Nitrazepam]]
*[[Omphalitis]]
*[[Opiate]]
*[[Osteogenesis imperfecta]]
*[[Oxymorphone]]
*[[Pleural effusion]]
*[[Pneumonia]]
*[[Pneumothorax]]
*[[Polio]]
*[[Polyrediculitis]]
*[[Post-polio syndrome]]
*[[Potter syndrome]]
*[[Pre-eclampsia]]
*[[Procainamide (patient information)]]
*[[Pulmonary alveolar proteinosis]]
*[[Pulmonary arterio-venous malformation]]
*[[Pulmonary edema]]
*[[Pulmonary embolism]]
*[[Pulmonary hypertension]]
*[[Pulmonary oedema]]
*[[Pulmonary valve stenosis]]
*[[Rabies]]
*[[Respiratory distress syndrome (neonatal)]]
*[[Restrictive Lung Disease]]
*[[Reye's syndrome]]
*[[Satoyoshi syndrome]]
*[[Saxitoxin]]
*[[Sepsis]]
*[[Smoke inhalation]]
*[[Snakebites (Patient information)]]
*[[Sodium thiopental]]
*[[Status asthmaticus]]
*Sulphur dioxide
*[[Tetanus]]
*[[Tetracycline antibiotics]]
*[[Tetrodotoxin]]
*[[Thanatophoric dysplasia]]
*[[Tick paralysis]]
*[[Transposition of great arteries]]
*[[Triazolam]]
*[[Tricuspid valve stenosis]]
*[[Ventricular septal defect]]
*[[Vinyl chloride]]
*[[Zellweger syndrome]]
*[[Zopiclone]]
{{EndMultiCol}}
 
===Complete Differential Diagnosis of the Causes of Respiratory failure===
(By organ system)
{|style="width:80%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |
[[Atrial septal defect (ostium primum)]],
[[Ebstein anomaly]],
[[Eisenmenger syndrome]],
[[Fallot tetralogy]],
[[Pulmonary valve stenosis]],
[[Transposition of great arteries]],
[[Tricuspid valve stenosis]],
[[Ventricular septal defect]],
 
|-
|-
|-bgcolor="LightSteelBlue"
| [[File:Siren.gif|30px|link=Respiratory failure resident survival guide]]|| <br> || <br>
| '''Chemical / poisoning'''
| [[Respiratory failure resident survival guide|'''Resident'''<br>'''Survival'''<br>'''Guide''']]
|bgcolor="Beige"| [[3-Quinuclidinyl benzilate]],
|}
[[Abrin]],
[[Aldicarb]],
[[Alpha-amanitin]],
[[Barium nitrate]],
[[Bungarotoxin]],
[[Carbon monoxide poisoning]],
[[Cocaine]],
[[Cone snail]],
[[Furfural]],
[[Snakebites (Patient information)]],


|-
'''For patient information, click [[Respiratory failure (patient information)|here]]'''
|-bgcolor="LightSteelBlue"
| '''Congenital'''
|bgcolor="Beige"|
[[Atrial septal defect (ostium primum)]],
[[Bland-White-Garland Syndrome]],
[[Congenital Central Hypoventilation Syndrome]],
[[Congenital diaphragmatic hernia]],
[[Fallot tetralogy]],
[[Fetal circulation, persistent]],
[[Respiratory distress syndrome (neonatal)]],


|-
{{Respiratory failure}}
|-bgcolor="LightSteelBlue"
{{CMG}}; {{AE}} {{MKA}}; {{HM}}
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect '''
|bgcolor="Beige"|


|-
{{SK}}: Acute respiratory failure, type I respiratory failure, type II respiratory failure, type III respiratory failure, type IV respiratory failure, type 1 respiratory failure, type 2 respiratory failure, type 3 respiratory failure, type 4 respiratory failure
|-bgcolor="LightSteelBlue"
==[[Respiratory failure overview|Overview]]==
| '''Ear Nose Throat'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Environmental'''
|bgcolor="Beige"|
[[Asbestosis]],
Coal worker pneumoconiosis,
[[Smoke inhalation]],
[[Sulphur dioxide]],


|-
==[[Respiratory failure historical perspective|Historical Perspective]]==
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
|bgcolor="Beige"|
[[Hepatic failure]],
[[Hepatopulmonary syndrome]],


|-
==[[Respiratory failure classification|Classification]]==
|-bgcolor="LightSteelBlue"
| '''Genetic'''
|bgcolor="Beige"|
[[Achondrogenesis]],
[[Acute Porphyria]],
[[Alpha 1-antitrypsin deficiency]],
[[Atelosteogenesis, type II]],
[[Becker's muscular dystrophy]],
[[Carnitine palmitoyltransferase II deficiency]],
[[Cystic fibrosis]],
[[Duchenne's Muscular Dystrophy]],
[[Familial dysautonomia]],
[[Hereditary haemorrhagic telangiectasia]],
[[Osteogenesis imperfecta]],
[[Thanatophoric dysplasia]],


|-
==[[Respiratory failure pathophysiology|Pathophysiology]]==
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
|bgcolor="Beige"|
[[Acute Porphyria]],
[[Cholesterol Emboli Syndrome]],
[[Fat embolism]],
[[Sepsis]],


|-
==[[Respiratory failure causes|Causes]]==
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
|bgcolor="Beige"|
[[Blood transfusion]],
[[EVAR]],


|-
==[[Respiratory failure differential diagnosis|Differentiating Respiratory Failure from other Diseases]]==
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
|bgcolor="Beige"|
[[Babesiosis]],
[[Botulism]],
[[Crimean-Congo hemorrhagic fever]],
[[Hantavirus Pulmonary Syndrome]],
[[Heartworm]],
[[Post-polio syndrome]],
[[Rabies]],
[[Tetanus]],


==[[Respiratory failure epidemiology and demographics|Epidemiology and Demographics]]==


|-
==[[Respiratory failure risk factors|Risk Factors]]==
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal / Ortho'''
|bgcolor="Beige"|
[[Kyphoscoliosis]],


|-
==[[Respiratory failure screening|Screening]]==
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
|bgcolor="Beige"|
[[Amyotrophic Lateral Sclerosis]],
[[Meningitis]],
[[Polyrediculitis]],
[[Zellweger syndrome]],


|-
==[[Respiratory_failure_natural_history,_complications_and_prognosis|Natural History, Complications and Prognosis]]==
|-bgcolor="LightSteelBlue"
| '''Nutritional / Metabolic'''
|bgcolor="Beige"|
[[Metabolic Acidosis]],
 
|-
|-bgcolor="LightSteelBlue"
| '''Obstetric/Gynecologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
|bgcolor="Beige"|
[[Malignant Mesothelioma]],
 
|-
|-bgcolor="LightSteelBlue"
| '''Opthalmologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Overdose / Toxicity'''
|bgcolor="Beige"|
[[Acetylsalicylic acid]],
[[Alcohol]],
[[Bufotenin]],
[[Clitocybe dealbata]],
[[Colchicine]],
[[Cytisine]],
[[Dicofol]],
[[Saxitoxin]],
[[Tetrodotoxin]],
[[Tick paralysis]],
[[Vinyl chloride]],
 
|-
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Pulmonary'''
|bgcolor="Beige"|
Acute lung syndrome,
[[Acute Respiratory Distress Syndrome]],
[[Alpha 1-antitrypsin deficiency]],
[[Atelectasis]],
[[Bronchial asthma]],
[[Bronchiectasis]],
[[Bronchiolitis]],
[[Bronchiolitis obliterans]],
[[Bronchogenic carcinoma]],
[[Bronchopulmonary dysplasia]],
[[Chronic Obstructive Pulmonary Disease]],
[[Cystic adenomatoid malformation of lung]],
[[Emphysema]],
[[Eosinophilic pneumonia]],
[[Fibrosing alveolitis]],
[[Flail chest]],
[[Interstitial fibrosis]],
[[Laryngo-/Bronchospasm]],
[[Legionella pneumophila]],
[[Pleural effusion]],
[[Pneumonia]],
[[Pneumothorax]],
[[Pulmonary alveolar proteinosis]],
[[Pulmonary arterio-venous malformation]],
[[Pulmonary edema]],
[[Pulmonary embolism]],
[[Pulmonary hypertension]],
[[Pulmonary oedema]],
[[Restrictive Lung Disease]],
[[Status asthmaticus]],
 
 
 
|-
|-bgcolor="LightSteelBlue"
| '''Renal / Electrolyte'''
|bgcolor="Beige"|
Elecrolyte abnormalities,
 
|-
|-bgcolor="LightSteelBlue"
| '''Rheum / Immune / Allergy'''
|bgcolor="Beige"|
[[Acute motor axonal neuropathy]],
[[Anaphylaxis]],
[[Angioedema]],
[[Antiphospholipid Antibody Syndrome]],
[[Devic's disease]],
[[Guillain-Barre syndrome]],
[[Hamman-Rich Syndrome]],
[[Myasthenia Gravis]],
[[Satoyoshi syndrome]],
 
 
 
|-
|-bgcolor="LightSteelBlue"
| '''Trauma'''
|bgcolor="Beige"|
[[Ebstein anomaly]],
[[Flail chest]],
 
|-
|-bgcolor="LightSteelBlue"
| '''Urologic'''
|bgcolor="Beige"| No underlying causes
|-
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
|bgcolor="Beige"|
[[Aspiration]],
[[Foreign body]],
[[Malignant hyperpyrexia]],
[[Multiple organ dysfunction syndrome]],
Near-drowning,
[[Reye's syndrome]],
 
|-
|}


==Diagnosis==
[[Respiratory failure diagnostic study of choice|Diagnostic Study of Choice]] |[[Respiratory failure history and symptoms|History and Symptoms]] | [[Respiratory failure physical examination|Physical Examination]] | [[Respiratory failure laboratory findings|Laboratory Findings]] | [[Respiratory failure electrocardiogram|Electrocardiogram]] | [[Respiratory failure chest x ray|Chest X Ray]] | [[Respiratory failure CT|CT]] | [[Respiratory failure MRI|MRI]] | [[Respiratory failure ultrasound|Echocardiography or Ultrasound]] | [[Respiratory failure other imaging findings|Other Imaging Findings]] | [[Respiratory failure other diagnostic studies|Other Diagnostic Studies]]


==Treatment==
==Treatment==
Emergency treatment follows the principles of [[cardiopulmonary resuscitation]]. Treatment of the underlying cause is required. [[Mechanical ventilation]] may be required.
[[Respiratory failure medical therapy|Medical Therapy]] | [[Respiratory failure surgery|Surgery]] | [[Respiratory failure primary prevention|Primary Prevention]] | [[Respiratory failure secondary prevention|Secondary Prevention]] | [[Respiratory failure cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] | [[Respiratory failure future or investigational therapies|Future or Investigational Therapies]]


==External Links==
==Case Studies==
[http://www.emedicine.com/med/topic2011.htm eMedicine Respiratory Failure]
[[Respiratory failure case study one|Case #1]]
[http://fr.wikipedia.org/wiki/Insuffisance_respiratoire]  


{{Respiratory pathology}}
{{Respiratory pathology}}
{{Intensive care medicine}}
{{Intensive care medicine}}
{{SIB}}


[[de:Ateminsuffizienz]]
[[de:Ateminsuffizienz]]
Line 510: Line 49:
[[pl:Niewydolność oddechowa]]
[[pl:Niewydolność oddechowa]]
[[:fr:Insuffisance respiratoire]]
[[:fr:Insuffisance respiratoire]]
[[Category:Surgery]]
[[Category:Up-To-Date]]
[[Category:Medicine]]
[[Category:Emergency medicine]]
[[Category:Emergency medicine]]
[[Category:Intensive care medicine]]
[[Category:Medical emergencies]]
[[Category:Organ failure]]
[[Category:Pulmonology]]
[[Category:Pulmonology]]
[[Category:Causes of death]]
[[Category:Anesthesiology]]
{{WikiDoc Help Menu}}
 
{{WikiDoc Sources}}
{{WH}}
{{WS}}

Latest revision as of 06:35, 28 July 2020



Resident
Survival
Guide

For patient information, click here

Respiratory failure Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Respiratory Failure from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

Electrocardiogram

CT

MRI

Echocardiography and ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical therapy

Oxygen therapy

Mechanical ventilation

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Respiratory failure On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Respiratory failure

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Respiratory failure

CDC on Respiratory failure

Respiratory failure in the news

Blogs on Respiratory failure

Directions to Hospitals Treating Type page name here

Risk calculators and risk factors for Respiratory failure

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]; Hadeel Maksoud M.D.[3]

Synonyms and keywords:: Acute respiratory failure, type I respiratory failure, type II respiratory failure, type III respiratory failure, type IV respiratory failure, type 1 respiratory failure, type 2 respiratory failure, type 3 respiratory failure, type 4 respiratory failure

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Respiratory Failure from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice |History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Chest X Ray | CT | MRI | Echocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies

Treatment

Medical Therapy | Surgery | Primary Prevention | Secondary Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies

Case Studies

Case #1

Template:Respiratory pathology

de:Ateminsuffizienz no:Respirasjonssvikt fr:Insuffisance respiratoire

Template:WH Template:WS