Difference between revisions of "Renal agenesis epidemiology and demographics"

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== Overview ==
 
== Overview ==
The general [[incidence]] of unilateral renal agenesis (URA) has been reported to be approximately 1 in 2031 individuals. [[Male|Males]] are more commonly affected by unilateral renal agenesis (URA) than [[Female|females]]. The [[incidence]] of bilateral renal agenesis (BRA) is approximately 1 in every 3000 pregnancies. The [[mortality rate]] of bilateral renal agenesis (BRA) without [[Prenatal development|prenatal]] therapy is 100%.
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The general [[incidence]] of unilateral renal agenesis (URA) has been reported to be approximately 1 in 2031 individuals. [[Male|Males]] are more commonly affected by unilateral renal agenesis (URA) than [[Female|females]]. The [[incidence]] of bilateral renal agenesis (BRA) is approximately 1 in every 3000 pregnancies. The [[mortality rate]] of bilateral renal agenesis (BRA) without [[Prenatal development|prenatal]] therapy is 100 %.
  
 
== Epidemiology and Demographics ==
 
== Epidemiology and Demographics ==

Latest revision as of 13:23, 2 August 2020

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shakiba Hassanzadeh, MD[2]

Overview

The general incidence of unilateral renal agenesis (URA) has been reported to be approximately 1 in 2031 individuals. Males are more commonly affected by unilateral renal agenesis (URA) than females. The incidence of bilateral renal agenesis (BRA) is approximately 1 in every 3000 pregnancies. The mortality rate of bilateral renal agenesis (BRA) without prenatal therapy is 100 %.

Epidemiology and Demographics

Incidence

  • The general incidence of unilateral renal agenesis (URA) has been reported to be approximately 1 in 2031 individuals, however, the incidence of URA based on prenatal studies alone has been reported to be 1 in 8091.[1]
  • The incidence of bilateral renal agenesis (BRA) is approximately 1 in every 3000 pregnancies.[2][3]

Prevalence

A report showed that the overall prevalence of unilateral renal agenesis (URA) was 4 per 10,000 in all births which included terminations of pregnancy (TOP) and intrauterine deaths (IUD).[4]

Mortality rate

The mortality rate of bilateral renal agenesis (BRA) without prenatal therapy is 100%.[5]

Gender

Males are more commonly affected by unilateral renal agenesis (URA) than females. It has been reported that 63% of the patients with URA are male.[1]

References

  1. 1.0 1.1 Westland R, Schreuder MF, Ket JC, van Wijk JA (2013). "Unilateral renal agenesis: a systematic review on associated anomalies and renal injury". Nephrol Dial Transplant. 28 (7): 1844–55. doi:10.1093/ndt/gft012. PMID 23449343.
  2. Bienstock JL, Birsner ML, Coleman F, Hueppchen NA (2014). "Successful in utero intervention for bilateral renal agenesis". Obstet Gynecol. 124 (2 Pt 2 Suppl 1): 413–5. doi:10.1097/AOG.0000000000000339. PMID 25004316.
  3. Isaksen CV, Eik-Nes SH, Blaas HG, Torp SH (2000). "Fetuses and infants with congenital urinary system anomalies: correlation between prenatal ultrasound and postmortem findings". Ultrasound Obstet Gynecol. 15 (3): 177–85. doi:10.1046/j.1469-0705.2000.00065.x. PMID 10846770.
  4. Laurichesse Delmas H, Kohler M, Doray B, Lémery D, Francannet C, Quistrebert J; et al. (2017). "Congenital unilateral renal agenesis: Prevalence, prenatal diagnosis, associated anomalies. Data from two birth-defect registries". Birth Defects Res. 109 (15): 1204–1211. doi:10.1002/bdr2.1065. PMID 28722320.
  5. Huber C, Shazly SA, Blumenfeld YJ, Jelin E, Ruano R (2019). "Update on the Prenatal Diagnosis and Outcomes of Fetal Bilateral Renal Agenesis". Obstet Gynecol Surv. 74 (5): 298–302. doi:10.1097/OGX.0000000000000670. PMID 31098643.