Radiation proctitis risk factors: Difference between revisions
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===Common Risk Factors=== | ===Common Risk Factors=== | ||
*Common risk factors in the development of radiation proctitis are the diseases that may increases the susceptibility of mucosal injury by radiation are: | *Common risk factors in the development of radiation proctitis are the diseases that may increases the susceptibility of mucosal injury by radiation are: | ||
**HIV<ref name="pmid10219805">{{cite journal| author=Hoffman R, Welton ML, Klencke B, Weinberg V, Krieg R| title=The significance of pretreatment CD4 count on the outcome and treatment tolerance of HIV-positive patients with anal cancer. | journal=Int J Radiat Oncol Biol Phys | year= 1999 | volume= 44 | issue= 1 | pages= 127-31 | pmid=10219805 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10219805 }}</ref> | **[[Human Immunodeficiency Virus (HIV)|HIV]]<ref name="pmid10219805">{{cite journal| author=Hoffman R, Welton ML, Klencke B, Weinberg V, Krieg R| title=The significance of pretreatment CD4 count on the outcome and treatment tolerance of HIV-positive patients with anal cancer. | journal=Int J Radiat Oncol Biol Phys | year= 1999 | volume= 44 | issue= 1 | pages= 127-31 | pmid=10219805 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=10219805 }}</ref> | ||
**Immunosuppresion<ref name="pmid20014399">{{cite journal| author=Housri N, Yarchoan R, Kaushal A| title=Radiotherapy for patients with the human immunodeficiency virus: are special precautions necessary? | journal=Cancer | year= 2010 | volume= 116 | issue= 2 | pages= 273-83 | pmid=20014399 | doi=10.1002/cncr.24878 | pmc=3409663 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20014399 }}</ref> | **Immunosuppresion<ref name="pmid20014399">{{cite journal| author=Housri N, Yarchoan R, Kaushal A| title=Radiotherapy for patients with the human immunodeficiency virus: are special precautions necessary? | journal=Cancer | year= 2010 | volume= 116 | issue= 2 | pages= 273-83 | pmid=20014399 | doi=10.1002/cncr.24878 | pmc=3409663 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20014399 }}</ref> | ||
**Inflammatory bowel disease | **[[Inflammatory bowel disease]] | ||
**Hx of smoking | **Hx of smoking | ||
**Diabetes Mellitus | **[[Diabetes mellitus|Diabetes Mellitus]] | ||
**Hypertension | **[[Hypertension]] | ||
**Hx of atherosclerosis | **Hx of atherosclerosis | ||
**Younger age | **Younger age | ||
**Concurrent treatment | **Concurrent treatment | ||
**Previous abdominal surgery | **Previous abdominal surgery | ||
**malnutrition | **[[malnutrition]] | ||
**tumour stage | **tumour stage | ||
**genotypic susceptibility to radiation toxicity | **genotypic susceptibility to radiation toxicity | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
Common risk factors in the development of radiation proctitis include include presence of inflammatory bowel disease. concurrent treatment, immunosuppression, co mordities and hx of previous surgery.
Risk Factors
Common Risk Factors
- Common risk factors in the development of radiation proctitis are the diseases that may increases the susceptibility of mucosal injury by radiation are:
- HIV[1]
- Immunosuppresion[2]
- Inflammatory bowel disease
- Hx of smoking
- Diabetes Mellitus
- Hypertension
- Hx of atherosclerosis
- Younger age
- Concurrent treatment
- Previous abdominal surgery
- malnutrition
- tumour stage
- genotypic susceptibility to radiation toxicity
References
- ↑ Hoffman R, Welton ML, Klencke B, Weinberg V, Krieg R (1999). "The significance of pretreatment CD4 count on the outcome and treatment tolerance of HIV-positive patients with anal cancer". Int J Radiat Oncol Biol Phys. 44 (1): 127–31. PMID 10219805.
- ↑ Housri N, Yarchoan R, Kaushal A (2010). "Radiotherapy for patients with the human immunodeficiency virus: are special precautions necessary?". Cancer. 116 (2): 273–83. doi:10.1002/cncr.24878. PMC 3409663. PMID 20014399.