Radiation proctitis history and symptoms: Difference between revisions
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{{CMG}}; {{AE}} | {{CMG}}; {{AE}} | ||
==Overview== | ==Overview== | ||
The most common symptoms of | The most common symptoms of radiation proctitis include mild [[diarrhea]], [[tenesmus]], fecal urgency and mucus discharge. Less common symptoms of radiation proctitis include [[abdominal pain]],[[constipation]],severe diarrhea and rectal bleeding. | ||
==History and Symptoms== | ==History and Symptoms== | ||
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*Recent hx of travel | *Recent hx of travel | ||
*Recent parasitic infection | *Recent parasitic infection | ||
*History or risk factors for STD | *History or risk factors for [[Sexually transmitted disease|STD]] | ||
*Recent use of antibiotics or NSAIDS | *Recent use of [[Antibiotic|antibiotics]] or [[Non-steroidal anti-inflammatory drug|NSAIDS]] | ||
*History of atherosclerosis | *History of atherosclerosis | ||
*Immunosuppression | *Immunosuppression | ||
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Less common symptoms of radiation proctitis include | Less common symptoms of radiation proctitis include | ||
*Abdominal pain | *Abdominal pain | ||
*Constipation | *[[Constipation]] | ||
*Severe Diarrhea | *Severe Diarrhea | ||
*Rectal bleeding | *Rectal bleeding | ||
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===Chronic radiation proctitis=== | ===Chronic radiation proctitis=== | ||
[[Image:Radiation proctitis APC.jpg|center|thumb|200px|[[Colonoscopy|Endoscopic]] image of radiation proctitis before and after therapy with [[argon plasma coagulation]].]] | [[Image:Radiation proctitis APC.jpg|center|thumb|200px|[[Colonoscopy|Endoscopic]] image of radiation proctitis before and after therapy with [[argon plasma coagulation]].]] | ||
Symptoms may begin as early as several months after therapy but occasionally not until several years later. These symptoms include diarrhea, [[Hematochezia|rectal bleeding]], painful defecation, and intestinal blockage. Intestinal blockage is a result of [[Stenosis|narrowing]] of the rectum which blocks the flow of [[feces]] due to stricture and results in symptoms in the form of constipation,rectal pain,urgency, and rarely, fecal incontinence due to overflow. Connections [[fistulae]] may also develop between the colon and other parts of the body such as the [[skin]] or [[urinary system]].Inury to the nearby organs can lead to cystitis,urethral stenosis,small bowel obstruction and small bowel bacterial overgrowth. | Symptoms may begin as early as several months after therapy but occasionally not until several years later. These symptoms include diarrhea, [[Hematochezia|rectal bleeding]], painful defecation, and intestinal blockage. Intestinal blockage is a result of [[Stenosis|narrowing]] of the rectum which blocks the flow of [[feces]] due to stricture and results in symptoms in the form of constipation,rectal pain,urgency, and rarely, fecal incontinence due to overflow. Connections [[fistulae]] may also develop between the colon and other parts of the body such as the [[skin]] or [[urinary system]].Inury to the nearby organs can lead to [[cystitis]],urethral stenosis,small bowel obstruction and small bowel bacterial overgrowth. | ||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
The most common symptoms of radiation proctitis include mild diarrhea, tenesmus, fecal urgency and mucus discharge. Less common symptoms of radiation proctitis include abdominal pain,constipation,severe diarrhea and rectal bleeding.
History and Symptoms
History
History plays a pivotal role in diagnosing the Radiaition proctitis and to exclude other differentials therefore history should include:
- Exposure to the radiation
- Recent hx of travel
- Recent parasitic infection
- History or risk factors for STD
- Recent use of antibiotics or NSAIDS
- History of atherosclerosis
- Immunosuppression
Common Symptoms
Common symptoms of Radiation proctitis include:
- Changes in bowel habits,usually mild diarrhea
- Tenesmus
- Fecal urgency
- Mucus discharge
Less Common Symptoms
Less common symptoms of radiation proctitis include
- Abdominal pain
- Constipation
- Severe Diarrhea
- Rectal bleeding
Acute radiation proctitis
Symptoms occur in the first few weeks after therapy. These symptoms include diarrhea and the urgent need to defecate, often with inability to do so (tenesmus). Acute radiation proctitis usually resolves without treatment after several months, but symptoms may improve with butyrate enemas. This acute phase is due to direct damage of the lining (epithelium) of the colon. [1]
Chronic radiation proctitis
Symptoms may begin as early as several months after therapy but occasionally not until several years later. These symptoms include diarrhea, rectal bleeding, painful defecation, and intestinal blockage. Intestinal blockage is a result of narrowing of the rectum which blocks the flow of feces due to stricture and results in symptoms in the form of constipation,rectal pain,urgency, and rarely, fecal incontinence due to overflow. Connections fistulae may also develop between the colon and other parts of the body such as the skin or urinary system.Inury to the nearby organs can lead to cystitis,urethral stenosis,small bowel obstruction and small bowel bacterial overgrowth.
References
- ↑ Babb RR. Radiation proctitis: a review. Am J Gastroenterol. 1996 Jul;91(7):1309-11. Review. PMID 8677984