Radiation proctitis differential diagnosis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].
OR
[Disease name] must be differentiated from [[differential dx1], [differential dx2], and [differential dx3].
Differentiating [Disease name] from other Diseases
[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].
The following conditions may present in a similar manner as radiation proctitis, and should be excluded:
- infectious colitis,
- inflammatory bowel disease,
- diversion colitis,
- ischemic colitis,
- chronic graft-versus-host disease,
- diverticular colitis, and
- medication-associated colitis
OR
[Disease name] must be differentiated from [differential dx1], [differential dx2], and [differential dx3].
OR
As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].
- The table below lists the differential diagnosis of common causes of colitis:
| Diseases | History and Symptoms | Physical Examination | Laboratory findings | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Diarrhea | Rectal bleeding | Abdominal pain | Atopy | History of radiation exposure | Dehydration | Fever | Hypotension | Malnutrition | Blood in stool (frank or occult) | Microorganism in stool | Pseudomembranes on endoscopy | |
| Allergic Colitis | + | ++ | + | ++ | ++ | |||||||
| Chemical colitis | + | ++ | ++ | + | + | ++ | + | |||||
| Infectious colitis | ++ | ++ | ++ | +++ | +++ | ++ | + | ++ | ++ | + | ||
| Radiation proctitis | + | ++ | + | ++ | + | + | ++ | |||||
| Ischemic colitis | + | + | ++ | + | + | + | + | ++ | ||||
| Drug-induced colitis | + | + | ++ | + | ++ | + | ||||||