RIT1

Ras-like without CAAX 1
Identifiers
Symbols	RIT1 ; MGC125864; MGC125865; RIBB; RIT; ROC1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 56003
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE RIT1 209882 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Ras-like without CAAX 1, also known as RIT1, is a human gene.

RIT belongs to the RAS (HRAS; MIM 190020) subfamily of small GTPases (Hynds et al., 2003).[supplied by OMIM]

Further reading

• Lee CH, Della NG, Chew CE, Zack DJ (1996). "Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins". J. Neurosci. 16 (21): 6784–94. PMID 8824319.CS1 maint: Multiple names: authors list (link)
• Wes PD, Yu M, Montell C (1997). "RIC, a calmodulin-binding Ras-like GTPase". EMBO J. 15 (21): 5839–48. PMID 8918462.CS1 maint: Multiple names: authors list (link)
• Shao H, Kadono-Okuda K, Finlin BS, Andres DA (1999). "Biochemical characterization of the Ras-related GTPases Rit and Rin". Arch. Biochem. Biophys. 371 (2): 207–19. doi:10.1006/abbi.1999.1448. PMID 10545207.CS1 maint: Multiple names: authors list (link)
• Shao H, Andres DA (2000). "A novel RalGEF-like protein, RGL3, as a candidate effector for rit and Ras". J. Biol. Chem. 275 (35): 26914–24. doi:10.1074/jbc.M002241200. PMID 10869344.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hynds DL, Spencer ML, Andres DA, Snow DM (2004). "Rit promotes MEK-independent neurite branching in human neuroblastoma cells". J. Cell. Sci. 116 (Pt 10): 1925–35. doi:10.1242/jcs.00401. PMID 12668729.CS1 maint: Multiple names: authors list (link)
• Li JT, Liu W, Kuang ZH; et al. (2004). "[Mutation and amplification of RIT1 gene in hepatocellular carcinoma]". Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 21 (1): 43–6. PMID 14767908.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shi GX, Andres DA (2005). "Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades". Mol. Cell. Biol. 25 (2): 830–46. doi:10.1128/MCB.25.2.830-846.2005. PMID 15632082.
• Barrios-Rodiles M, Brown KR, Ozdamar B; et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Benmaamar R, Pagano M (2006). "Involvement of the SCF complex in the control of Cdh1 degradation in S-phase". Cell Cycle. 4 (9): 1230–2. PMID 16123585.