RGS6

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
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RefSeq (mRNA)

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RefSeq (protein)

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Regulator of G-protein signaling 6 is a protein that in humans is encoded by the RGS6 gene.[1][2][3]

Members of the RGS (regulator of G protein signaling) family have been shown to modulate the functioning of G proteins by activating the intrinsic GTPase activity of the alpha (guanine nucleotide-binding) subunits.[supplied by OMIM][3]

Interactions

RGS6 has been shown to interact with STMN2[4] and DMAP1.[2]

References

  1. Seki N, Hattori A, Hayashi A, Kozuma S, Hori T, Saito T (April 1999). "The human regulator of G-protein signaling protein 6 gene (RGS6) maps between markers WI-5202 and D14S277 on chromosome 14q24.3". J Hum Genet. 44 (2): 138–40. doi:10.1007/s100380050129. PMID 10083744.
  2. 2.0 2.1 Liu Z, Fisher RA (March 2004). "RGS6 interacts with DMAP1 and DNMT1 and inhibits DMAP1 transcriptional repressor activity". J Biol Chem. 279 (14): 14120–8. doi:10.1074/jbc.M309547200. PMID 14734556.
  3. 3.0 3.1 "Entrez Gene: RGS6 regulator of G-protein signalling 6".
  4. Liu, Zhengyu; Chatterjee Tapan K; Fisher Rory A (October 2002). "RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6". J. Biol. Chem. United States. 277 (40): 37832–9. doi:10.1074/jbc.M205908200. ISSN 0021-9258. PMID 12140291.

Further reading