Q fever natural history, complications, and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]

Overview

Acute Q fever has a good prognosis even without treatment. Chronic Q fever has a less favorable prognosis.

Natural history

Acute Q fever

  • If left untreated, most patients will recover within several month.[1]

Chronic Q fever

  • If left untreated, it is usually deadly. However, with appropriate treatment this lethality is around 10%.[1]

Complications

Pulmonary

Cardiac

Hepatic

Musculoskeletal

Obstetric

Prognosis

Acute Q fever

  • Acute Q fever is responsive to treatment and even without treatment, mortality rate is 1-2%.

Chronic Q fever

  • Chronic Q fever is more serious with lethaity of 10% after treatment.[2]

References

  1. 1.0 1.1 Ishikawa H, Maeda H, Takamatsu H, Saito Y (1979). "Systemic hyalinosis (juvenile hyaline fibromatosis). Ultrastructure of the hyaline with particular reference to the cross-banded structure". Arch. Dermatol. Res. 265 (2): 195–206. PMID 88923.
  2. Hartzell JD, Wood-Morris RN, Martinez LJ, Trotta RF (2008). "Q fever: epidemiology, diagnosis, and treatment". Mayo Clin. Proc. 83 (5): 574–9. doi:10.4065/83.5.574. PMID 18452690.

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