Pyridoxine deficiency causes

Revision as of 11:55, 25 July 2016 by Irfan Dotani (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search


Pyridoxine deficiency Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Pyridoxine deficiency from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Pyridoxine deficiency causes On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Pyridoxine deficiency causes

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Pyridoxine deficiency causes

CDC on Pyridoxine deficiency causes

Pyridoxine deficiency causes in the news

Blogs on Pyridoxine deficiency causes

Directions to Hospitals Treating Cushing’s disease

Risk calculators and risk factors for Pyridoxine deficiency causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.

Overview

The classic clinical syndrome for Pyridoxine deficiency (or B6 deficiency) is a seborrheic dermatitis-like eruption, atrophic glossitis with ulceration, angular cheilitis, conjunctivitis, intertrigo, and neurologic symptoms of somnolence, confusion, and neuropathy.[1] Vitamin B6 is a co-factor for glutamic acid decarboxylase, an enzyme that converts Glutamate to GABA. Therefore, the concurrent increase in the excitatory neurotransmitter, Glutamate, and decrease in inhibitory neurotransmitter, GABA, resultant from B6 deficiency, may manifest itself in the form of seizures.

Causes

  • Supporters of a debated medical condition known as Pyroluria believe it may be one potential cause of vitamin B6 deficiency.
  • Another cause of vitamin B6 deficiency is the use of the tuberculostatic medication isoniazid, and for this reason, it is recommended to supplement with vitamin B6 when using this drug.
  • Grumpiness and irritability are also often symptomatic of a deficiency according to "Body, Mind, and the B Vitamins" by Ruth Adams and Frank Murray.
  • A meta-analysis of three databases (MEDLINE, EMBASE, and Cochrane Library), including only double-blind, randomized controlled trials, found that vitamin B6 has a significant effect compared to placebos in treating morning sickness, similar to that of ginger.[2]

References

Template:WS Template:WH