https://www.wikidoc.org/index.php?title=Pyknosis&feed=atom&action=historyPyknosis - Revision history2024-03-29T01:31:41ZRevision history for this page on the wikiMediaWiki 1.40.0https://www.wikidoc.org/index.php?title=Pyknosis&diff=724323&oldid=prevWikiBot: Robot: Automated text replacement (-{{reflist}} +{{reflist|2}}, -<references /> +{{reflist|2}}, -{{WikiDoc Cardiology Network Infobox}} +)2012-09-06T14:08:55Z<p>Robot: Automated text replacement (-{{reflist}} +{{reflist|2}}, -<references /> +{{reflist|2}}, -{{WikiDoc Cardiology Network Infobox}} +)</p>
<p><b>New page</b></p><div>[[Image:nuclear changes.jpg|thumb|right|350px|Morphological characteristics of pyknosis and other forms of nuclear destruction]]<br />
'''Pyknosis''', or '''karyopyknosis''', is the irreversible condensation of [[chromatin]] in the [[nucleus]] of a [[cell (biology)|cell]] undergoing [[programmed cell death]] or apoptosis <ref name="zamzami">{{cite journal | author=Zamzami N, Kroemer G.| title=Apoptosis: Condensed matter in cell death| journal=Nature| year=1999| volume=401| issue=127| url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10490018}}</ref>. It is followed by [[karyorrhexis]], or fragmentation of the nucleus.<br />
Pyknosis is also observed in the maturation of erythrocytes (a [[red blood cell]]) and the [[neutrophil]] (a type of white blood cell). The maturing metarubicyte (a stage in RBC maturation) will condense its nucleus before expelling it to become a reticulocyte. The maturing neutrophil will condense its nucleus into several connected lobes that stay in the cell until the end of its cell life.<br />
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== See also ==<br />
*[[Apoptosis]]<br />
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== References ==<br />
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[[Category:Cellular processes]]<br />
[[Category:Programmed cell death]]<br />
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{{Cell-biology-stub}}<br />
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[[ru:Кариопикноз]]</div>WikiBot